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    What is an Extended Thyroid Profile Test?

    Thyroid tests evaluate the performance of the thyroid gland, a small butterfly-shaped gland in the neck that produces hormones like T3 (triiodothyronine) and T4 (thyroxine). These hormones regulate energy usage in the body and influence various vital functions such as heart rate, breathing, digestion, weight, and mood. T3 is the active form that directly affects metabolism, while T4 acts as a backup and stays in the body longer. If you are experiencing symptoms like fatigue, irritability, sluggishness, or unexplained weight changes, your doctor may recommend a Thyroid test. This test helps diagnose thyroid disorders like hyperthyroidism (high thyroid hormone levels) and hypothyroidism (low thyroid hormone levels).

    The Extended Thyroid Profile measures thyroid-stimulating hormone (TSH), total thyroxine (T4), total triiodothyronine (T3), free T4 (FT4), and free T3 (FT3). TSH, produced by the pituitary gland, regulates the thyroid’s production of T4 and T3. Thyroid hormones exist in bound and free forms; T4 and T3 are bound to transport proteins, and in their free forms (FT4 and FT3), they can enter tissues and exert effects on the body.

    In fast-paced cities like Gurgaon, symptoms of thyroid disorders, such as fatigue and irritability, are sometimes easy to overlook. If you experience these symptoms, consider getting an Extended Thyroid Profile test in Gurgaon today.

    Extended Thyroid Profile Test Parameters

    The Extended Thyroid Profile evaluates five vital factors to assess thyroid function:

    TSH

    Produced by the pituitary gland, it stimulates the thyroid to produce T4 and T3.

    Total T4

    Measures the total T4 hormone, including the bound form that cannot enter tissues.

    Total T3

    Assesses the total T3, including its bound form, which is inactive and cannot enter tissues.

    Free T4

    Measures the free, biologically active form of T4 that can affect tissues.

    Free T3

    Evaluates the unbound, biologically active T3 that can directly enter tissues.

    TSH regulates the thyroid's production of hormones through a feedback loop: low T4 raises TSH, and high T4 lowers it. T4 is converted to T3, mostly in the liver and brain. This test provides a detailed view of thyroid health, helping diagnose and treat thyroid disorders.

    Extended Thyroid Profile Test Preparation

    Note the following points before scheduling an Extended Thyroid Profile test at home:

    • Prerequisites

    Fasting is not typically required for an Extended Thyroid Profile, though in some cases, your doctor may advise it for improved accuracy. It’s important to check with your doctor to see if fasting is needed for your specific health condition.

    • Best Time to Get Tested

    Morning is the optimal time for thyroid testing, as food may impact the results. Scheduling tests consistently at the same time each day can help ensure reliable comparisons over time.

    • Who Should Get an Extended Thyroid Profile Test

    Anyone with symptoms like fatigue, sluggishness, restlessness, irritability, or unexplained weight fluctuations should consider taking this test. It’s also advised for people with a family history of thyroid disorders, pregnant women, those with fertility issues, or individuals on thyroid medications to monitor their treatment.

    • Cautions Before Taking an Extended Thyroid Profile Test

    No specific preparation is necessary, but it’s crucial to inform your doctor about any medications you're taking, especially those for thyroid conditions.

    Why Take a Extended Thyroid Profile Test?

    Thyroid hormone abnormalities can have significant effects on your health. An Extended Thyroid test could be necessary if you are:

    • Experiencing hyperthyroidism-related symptoms such as:

    • Rapid heartbeat

    • Excessive sweating

    • Heat sensitivity

    • Weight loss

    • Sleeping problems

    • Nervousness

    • Increased bowel movements

    • Light or absent menstruation

    People with the following conditions may also find it necessary to have a Thyroid test:

    • Turner syndrome

    • Pregnancy

    • Residence in an area without iodised salt, which increases the risk of iodine deficiency

    • Taking thyroid hormone replacement therapy

    • Age over 60, particularly women

    • Undergoing infertility investigations

    • History of radiation therapy to the head and/or neck

    • Autoimmune diseases, such as:

      • Addison’s disease (primary adrenal insufficiency)

      • Pernicious anaemia

      • Rheumatoid arthritis

      • Type 1 diabetes

      • Celiac disease

      • Lupus

      • Sjögren’s syndrome

    Extended Thyroid Profile Test Results & Interpretation

    The table below provides the normal ranges for different parameters included in the Extended Thyroid Profile test:

    Test ParameterReference Range
    Triiodothyronine (T3), Free2.77-5.27 pg/mL
    Thyroxine (T4), Free0.78-2.19 ng/dL
    Triiodothyronine (T3), Total0.97-1.69 ng/dL
    Thyroxine (T4), Total5.53-11.0 µg/dL
    Thyroid Stimulating Hormone (TSH)0.400-4.049 µIU/mL

    However, in pregnant women, the reference range for TSH differs. For the precise values, please see the table below:

    TrimesterReference Range (µIU/mL)
    1st Trimester0.100-2.500
    2nd Trimester0.200-3.00
    3rd Trimester0.300-3.00

    Interpretation of Abnormal levels

    T4 and FT4

    Low T4/FT4 levels may indicate:

    • Hypothyroidism

    • Congenital hypothyroidism (present from birth in infants)

    • Medication side effects

    • Thyroiditis (inflammation of the thyroid gland)

    High T4/FT4 levels may indicate:

    • Hyperthyroidism

    • Excess dietary iodine

    • Thyroiditis

    • A tumour (noncancerous) in the pituitary gland

    • Overactive thyroid gland with a lump or areas that produce excess thyroid hormones (toxic nodule/goitre)

    T3 and FT3

    High T3/FT3 Levels:

    • Indicate hyperthyroidism

    • With normal or high TSH and high FT4 indicate a pituitary gland issue causing excess thyroid hormone secretion

    • With low TSH and high FT4 indicate a thyroid gland problem causing excess thyroid hormone secretion

    Low T3/FT3 Levels:

    • Indicate hypothyroidism

    • Normal or low T3 levels with high TSH and low FT4 suggest a thyroid gland issue causing less secretion of thyroid hormone

    • Normal or low T3 levels with low TSH and low FT4 suggest a pituitary gland problem causing less secretion of thyroid hormone

    TSH Levels

    High levels of TSH typically indicate primary hypothyroidism (caused due to issues in the thyroid gland).

    Low TSH levels suggest hyperthyroidism.

    Factors Influencing TSH Levels

    • Meal Timings and Circadian Rhythm : TSH levels can fluctuate with food intake and throughout the day. Significant variations are observed both with meal consumption and at different times of the day.

    • Additional Influences : TSH is a sensitive hormone influenced by factors beyond thyroid function. These include stress, physical activity, genetic factors, exposure to toxins and radiation, thyroid gland inflammation, iodine levels in the diet, pregnancy, non-thyroidal pituitary factors (such as glucocorticoids, somatostatin, and dopamine), and certain medications that can impact the TSH and free T4 relationship.

    FAQs on Extended Thyroid Profile Test in Gurgaon

    The Extended Thyroid Profile test price is ₹ 1270. This cost covers the fastest home sample collection within 60 minutes of test booking, with results available in 6 hours.

    Yes, Orange Health Labs offers home sample collection services for the Extended Thyroid Profile test in Gurgaon. Your sample can be collected from your home within 60 minutes of test confirmation, depending on available time slots.

    This test is used to:

    • Evaluate thyroid health by measuring TSH, FT4, total T4, FT3, and total T3 levels.

    • Diagnose thyroid disorders like hypo- and hyperthyroidism.

    • Monitor hormone replacement treatment and assess conditions affecting the pituitary gland.

    • Detect thyroid inflammation, iodine imbalance, and tumour development.

    No, you are not required to fast for an Extended Thyroid Profile test.

    To book your blood test or health checkup through our platform, here’s what to do:

    • Search for the Test : Look for the Extended Thyroid Profile test in Gurgaon or at home and visit the Orange Health page from the search results.

    • Review and Confirm : Select the test, check for prerequisites, enter your location, and set a suitable time for the sample collection.

    • Sample Collection : A trained eMedic will come to your home to collect the sample at the scheduled time.

    • Lab Processing : The sample will be sent to an ICMR-approved, NABL-accredited lab for analysis.

    • Results : Test results will be sent via email or WhatsApp within 6 hours and will be accessible via our app.

    The normal levels for an Extended Thyroid Profile are:

    • FT3: 2.77-5.27 pg/mL

    • FT4: 0.78-2.19 ng/dL

    • Total T3: 0.97-1.69 ng/mL

    • Total T4: 5.53-11.0 µg/dL

    • TSH: 0.400-4.049 µIU/mL

    However, for pregnant women, the reference ranges for TSH levels vary by trimester, as follows:

    • 1st Trimester: 0.100 - 2.500 µIU/mL

    • 2nd Trimester: 0.200 - 3.000 µIU/mL

    • 3rd Trimester: 0.300 - 3.000 µIU/mL

    After you book the Extended Thyroid Profile test, an eMedic from Orange Health Labs will arrive to collect your sample within 60 minutes. The sample collection typically takes only a few minutes. Your reports will be available online within 6 hours.

    The frequency of the Extended Thyroid Profile test is tailored to your individual health needs. Always adhere to your doctor’s advice regarding how often you should have the test based on your specific health condition.

    The Extended Thyroid Profile test includes the following 5 parameters:

    • Free T3

    • Total T3

    • Free T4

    • Total T4

    • TSH

    Orange Health brings fast Extended Thyroid Profile test services directly to your home across Gurgaon, so you don’t need to visit a physical lab. We cater to a variety of local areas, including but not limited to DLF Phase 1, DLF Phase 2, DLF Phase 3, DLF Phase 4, DLF Phase 5, Sector 14, Sector 15, Sector 21, Sector 22, Sector 23, Sector 24, Sector 29, Sector 31, Sector 40, Sector 42, Sector 43, Sector 45, Sector 46, Sector 50, Sector 51, Sector 52, Sector 53, Sector 54, Sector 55, Sector 56.

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    References

    1. Thyroid Tests [Internet]. MedlinePlus.  Available from:  https://medlineplus.gov/thyroidtests.html
    2. Thyroid function tests [Internet]. Health Direct.  Available from:  https://www.healthdirect.gov.au/thyroid-function-tests
    3. Thyroid Hormone [Internet]. Cleveland Clinic.  Available from:  https://my.clevelandclinic.org/health/articles/22391-thyroid-hormone
    4. Thyroid Tests [Internet]. Cleveland Clinic.  Available from:  https://my.clevelandclinic.org/health/diagnostics/17556-thyroid-blood-tests