Search for
Mins HomeCollection
HappyCustomers
GoogleRating
CertifiedLabsWhat is Tissue Transglutaminase antibody IgA Test?
The Anti-Tissue Transglutaminase (tTG-IgA) blood test is a precise and effective diagnostic tool used to identify coeliac disease and dermatitis herpetiformis. Coeliac disease is a condition where the body’s immune system wrongly identifies gluten, a protein present in wheat, rye, barley, and oats, as harmful. This reaction leads to the formation of antibodies that attack tissue transglutaminase (tTG), an enzyme vital for maintaining the health of the intestinal lining.
The tTG-IgA test is typically recommended for individuals experiencing digestive issues or symptoms that could indicate coeliac disease. It is also suggested for those with a family history of gluten-related conditions, thyroid abnormalities, type 1 diabetes, or autoimmune disorders associated with gluten sensitivity.
In Hyderabad, individuals suspecting gluten intolerance or coeliac disease can easily book an Anti Tissue Transglutaminase test at home.
Tissue Transglutaminase antibody IgA Test Parameters
The tTG-IgA test checks for specific antibodies, called IgA anti-tissue transglutaminase, which are markers of coeliac disease.
These antibodies form when the immune system mistakenly attacks an enzyme called tissue transglutaminase (tTG) after gluten is consumed. The test is highly accurate, with over 90% reliability for diagnosing coeliac disease and monitoring its progression.
These antibodies often show up early, even before symptoms like bloating or diarrhea become noticeable. In untreated cases, both IgA anti-tTG and IgA anti-endomysial antibodies are usually present. Following a gluten-free diet lowers these antibodies over time, and they may eventually disappear. This test helps confirm coeliac disease and monitor dietary compliance.
Tissue Transglutaminase antibody IgA Test Preparation
Follow these steps to prepare for the IgA anti-tTG test:
Prerequisites: Fasting is not needed for the Anti Tissue Transglutaminase test, so you can eat normally before the appointment.
Best Time to Get Tested: You can schedule the Anti Tissue Transglutaminase test at any point during the day that suits you.
Who Should Get an Anti-Tissue Transglutaminase Test?: The test is advised for people showing signs of coeliac disease, such as frequent diarrhoea, stomach pain, slow growth, or unexplained skin rashes. It’s also suggested for those with a family history of coeliac disease or related conditions like type 1 diabetes or thyroid issues.
Cautions Before Taking an Anti-Tissue Transglutaminase Test: For accurate results, the test should be done while eating a gluten-containing diet. Avoiding gluten could lower antibody levels, leading to incorrect results.
Why Take the Tissue Transglutaminase antibody IgA Test?
The Anti-Tissue Transglutaminase test may be recommended if you:
● Show symptoms associated with coeliac disease , including:
o Abdominal discomfort
o Ongoing diarrhoea
o Constipation
o Bloating
o Vomiting
o Persistent skin rashes
o Slowed growth
● Have a family history of coeliac disease , which raises the likelihood of developing it.
● Suffer from autoimmune conditions , such as thyroid disorders or type 1 diabetes, as they are often linked to coeliac disease.
FAQs on Tissue Transglutaminase antibody IgA Test in Hyderabad
The Anti-Tissue Transglutaminase test costs ₹1309 in Hyderabad. This includes home sample collection within 60 minutes of booking, with results provided within 96 hours after the sample is collected.
Yes, Orange Health Labs provides home collection services for the Anti-Tissue Transglutaminase test. A trained eMedic will arrive at your preferred location in 60 minutes to collect the sample safely and conveniently.
This test identifies IgA antibodies targeting tissue transglutaminase, helping to confirm coeliac disease or gluten sensitivity. It is also used for monitoring the effectiveness of a gluten-free diet and is suggested for conditions like dermatitis herpetiformis or autoimmune disorders associated with coeliac disease.
No fasting is required to take the Anti-Tissue Transglutaminase test.
To book an Anti-Tissue Transglutaminase test with Orange Health Labs, follow these steps:
● Search and Select : Find “Anti-Tissue Transglutaminase Test” on the Orange Health Labs website or app.
● Confirm Details : Provide your personal information and choose your location and preferred time slot.
● Sample Collection : A trained professional will visit your location to collect the sample.
● Laboratory Processing : The sample will be analysed in an NABL-certified and ICMR-accredited laboratory.
● Get Results : The test results will be sent to you via email or WhatsApp within 96 hours.
The IgA anti-tTG levels are usually negative under normal conditions. A positive result may strongly suggest coeliac disease or gluten sensitivity.
In Hyderabad, the test results are ready within 96 hours after the sample collection process is completed.
Your doctor will decide the frequency based on your condition. It is generally conducted during diagnosis and repeated periodically to monitor compliance with a gluten-free diet and track disease progress.
The test evaluates the presence of IgA anti-tTG antibodies, which indicate an immune reaction against tissue transglutaminase, crucial in diagnosing coeliac disease.
Orange Health Labs offers home sample collection for the Anti-Tissue Transglutaminase test in various Hyderabad localities, including Banjara Hills, Jubilee Hills, Gachibowli, Madhapur, Hitech City, Kondapur, Begumpet, Somajiguda, Ameerpet, Panjagutta, Kukatpally, Miyapur, Manikonda, Secunderabad, Tarnaka, Abids, Koti, Mehdipatnam, Dilsukhnagar, Uppal, LB Nagar, Nallagandla, Nizampet, Attapur, Malkajgiri.
Payment & Refund Policy
- We do not accept cash payments
- All modes of online payment are accepted
- Refunds will be credited back to the source of payment within 5-7 working days of order cancellation.
References
- Blood Test: Tissue Transglutaminase IgA (tTg-IgA) (for Parents). Available from: https://kidshealth.org/en/parents/test-ttg.html
- Tissue Transglutaminase Antibody (TTG) - South Tees Hospitals NHS Foundation Trust. Available from: https://www.southtees.nhs.uk/services/pathology/tests/tissue-transglutaminase-antibody-ttg/
- Pathology Handbook. Available from: https://www.pathology.med.umich.edu/handbook/#/details/1217