The Gliadin Deamidated Peptide Antibody IgG test is designed to detect antibodies against gliadin in the blood, assisting in identifying coeliac disease or gluten sensitivity. In individuals with coeliac disease, consuming gluten—found in wheat, rye, and barley—triggers an immune response that damages the small intestine. This affects the intestinal villi, impairing the body's ability to absorb essential nutrients and leading to symptoms like fatigue, stomach pain, anaemia, bone weakness, and unexplained weight loss.

If the IgG test is positive, further investigations, such as a small intestine biopsy, may be required for a definitive diagnosis. Coeliac disease can manifest at any stage of life but is most often detected in infants (8–12 months) or adults between 40 and 60 years of age. Many cases go undiagnosed due to nonspecific symptoms. Individuals with a family history of coeliac disease or other autoimmune disorders should consider testing, even if they don’t exhibit symptoms.

For those in Gurgaon, the Gliadin Deamidated Peptide Antibody IgG test is available as a home testing option for detecting gluten-related immune reactions.

To prepare for the Gliadin Deamidated Peptide Antibody IgG test:

• Prerequisites: The test does not require special preparations like fasting.

• Best Time to Get Tested :

This test is flexible and can be conducted at any time of day without specific restrictions.

• Who Should Get a Gliadin Deamidated Peptide Antibody IgG Test?: If you experience symptoms of coeliac disease, such as diarrhoea, bloating, fatigue, or rashes, or have unexplained weight loss, nutrient deficiencies, or autoimmune disorders, you should consider this test.

• Cautions Before Taking a Gliadin Deamidated Peptide Antibody IgG Test: There are no special requirements before the test. However, keep a normal diet that includes gluten. Stopping gluten intake weeks before testing could lower antibody levels, resulting in a false-negative outcome even if coeliac disease is present.

If you suspect coeliac disease, consider taking this test. Symptoms can vary significantly, but common signs include:

• Digestive Issues:

• • Stomach pain and bloating

  • Frequent diarrhoea

  • Pale, greasy, or bad-smelling stools

  • Gas and constipation

• Physical and Neurological Symptoms:

• • Unexplained weight loss

  • Tingling or numbness in hands and feet

  • Mouth sores

• Mood and Skin Changes:

• • Itchy skin rashes

  • Chronic fatigue

  • Persistent feelings of anxiety or sadness

This test is also recommended if you have trouble absorbing nutrients like iron, folate, vitamin B12, calcium, or vitamin D, even without obvious symptoms.

People with certain health conditions, such as type 1 diabetes, Down syndrome, or other genetic disorders, are at a higher risk of developing coeliac disease. Other scenarios that might warrant testing include:

• Frequent headaches

• Delayed growth in children

• Challenges with fertility.