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    Cancer Antigen 125 (CA 125)2400160033% off
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    What Is Cancer Antigen 125 (CA 125) Test?

    The Cancer Antigen 125 (CA-125) test measures the level of a protein called CA-125 in the blood. CA-125 is a type of tumour marker (indicator) that may be elevated in certain types of cancer, particularly ovarian cancer. The ovaries are a pair of reproductive organs in females that store and release eggs and secrete female hormones. CA-125 is produced by the cells lining the ovary and other organs, such as the fallopian tubes and uterus. High levels of CA-125 are seen in various cancers as well as other health conditions.

    The CA-125 test is used to screen postmenopausal women who have a high risk of developing ovarian cancer, such as those with a family history or genetic predisposition for ovarian cancer. The test is also used to evaluate individuals with symptoms suggestive of ovarian cancer. The CA-125 test is particularly useful to monitor the efficacy and progress of ovarian cancer treatment and to check for cancer recurrence after treatment.

    If you are someone residing in Bangalore and have risk factors or symptoms suspected of ovarian cancer, you may undergo a CA-125 test at home with your doctor’s recommendation to monitor your health or assess your risk.

    Cancer Antigen 125 (CA 125) Test Parameters

    The Cancer Antigen 125 (CA-125) test measures a single parameter – CA-125 protein levels in the bloodstream.

    CA125 is a tumour marker produced by ovarian cancer cells and the cells lining organs like the endometrium, fallopian tubes, lungs (pleura), gut (peritoneum), and heart (pericardium). It's utilised in serological tests when ovarian cancer is suspected and for monitoring patients already diagnosed with epithelial ovarian cancers. CA-125 is believed to suppress the immune system’s ability to eliminate diseased cells, such as infected cells and cancer cells.

    Normally, CA-125 stays on the cell surface and does not enter the bloodstream as there are protective barriers in place. However, once these barriers are destroyed by cancerous cells, CA-125 leaks into the blood, leading to increased levels that are detectable by tests. CA-125 also appears to interact with other cellular proteins to promote the growth and spread of cancer.

    Elevated CA-125 levels are usually seen in ovarian cancer, particularly epithelial ovarian cancer. However, increased CA-125 may also be seen in other cancers, such as cancer of the uterus, breast, and fallopian tubes, and in benign (non-cancerous) conditions like ovarian cysts, fibroids, and endometriosis. High levels of CA-125 can also be seen in physiological (normal body) conditions such as the first trimester of pregnancy, the postpartum period, and menstruation.

    Cancer Antigen 125 (CA 125) Test Preparation

    Preparing for a Cancer Antigen 125 test at home is simple with these steps:

    Pre-requisites

    Fasting is not required for the Cancer Antigen 125 (CA-125) test.

    Best Time to Get Tested

    The Cancer Antigen 125 (CA 125) test can be done at any time during the day.

    Who Should Get a Cancer Antigen 125 (CA-125) Test

    The CA-125 test is advisable for diagnosing ovarian cancer in women with symptoms or risk factors, such as a family history or genetic changes. The test is also suitable for monitoring individuals diagnosed with ovarian cancer and undergoing treatment. It may also be done regularly after treatment to check if the cancer has returned.

    Cautions Before Taking a Cancer Antigen 125 (CA-125) Test

    It is important to be aware that CA-125 levels can be elevated in non-cancerous conditions, such as pregnancy, menstruation, and fibroids. Ask your doctor about any precautionary measures needed before testing.

    Why Take the Cancer Antigen 125 (CA 125) Test?

    A CA-125 test is a valuable tool for various reasons related to ovarian cancer management and risk assessment. Here’s why you might need this test:

    • Monitor Treatment Progress : If you have been diagnosed with ovarian cancer, CA-125 tests are done regularly during treatment to assess whether the therapy is effective. A decrease in CA-125 levels typically indicates that the treatment is working.

    • Check for Recurrence : After completing cancer treatment, CA-125 levels may be periodically monitored, every few months or every year, to detect if the cancer has returned.

    • Evaluate Pelvic Lumps : If a suspicious lump is found in the pelvic area during imaging tests, like an ultrasound, CA-125 levels can help determine if the lump could be ovarian cancer.

    • Assessment of High-Risk Individuals : CA-125 levels may be checked in individuals with a significantly higher risk of ovarian cancer, such as those with:

    • A family history of ovarian cancer, breast cancer, or colorectal cancer.

    • Specific genetic mutations (changes in genes, including the BRCA1 or BRCA2 genes).

    • Hereditary conditions such as Lynch syndrome that increase the likelihood of many types of cancer.

    • A history of ovarian, breast, colorectal, or uterine (uterus) cancer.

    Since high levels of CA-125 can show up in several other conditions, the CA-125 test is often used in conjunction with other diagnostic tools and tests to confirm the diagnosis.

    Cancer Antigen 125 (CA 125) Test Results and Interpretation

    Cancer Antigen 125 is a tumour marker for monitoring the therapy and progress of patients with serous ovarian cancer. The table below gives the normal level of CA-125 protein in the blood as well as the conditions associated with high levels:

    TestBiological Reference (U/mL)Interpretation
    CA-125 (Serum)<35CA-125 is found in a high percentage of non-mucinous ovarian tumours of epithelial origin. Elevated levels are also found in ovarian cysts, endometriosis, cervicitis, cirrhosis, hepatitis, malignancy of endometrium, breast, or gastrointestinal tract.

    FAQs on Cancer Antigen 125 (CA 125) Test

    The cost of a Cancer Antigen 125 test in Bangalore is 1600. This cost includes quick home sample collection from your desired location.

    Yes, Orange Health Labs offers home sample collection services for the CA-125 test in Bangalore. A skilled and professional eMedic will arrive at your preferred location within 60 minutes of booking, or at a time that suits you, ensuring a convenient and hassle-free experience.

    The CA-125 test is mainly used during the diagnosis, treatment, and monitoring of ovarian cancer. It helps screen individuals at high risk or with symptoms of ovarian cancer. The test is most commonly used during ovarian cancer treatment, to assess treatment effectiveness and detect cancer recurrence.

    No, fasting is not required for a CA-125 test.

    To schedule a blood test or health checkup with Orange Health Labs, follow these steps:

    • Search for the Test : Search for the Cancer Antigen 125 test in Bangalore or the Cancer Antigen 125 (CA 125) test at home and click on Orange Health Lab’s listing.

    • Review and Book : Select the test, check the prerequisites, enter your address, and confirm your booking by choosing a suitable time slot for sample collection.

    • Sample Collection : A skilled and experienced eMedic will arrive at your location within your selected time slot to collect the sample.

    • Lab Processing : The collected sample will be sent to our NABL-accredited and ICMR-approved laboratory for analysis.

    • Receive Results : You are likely to receive your reports via email or WhatsApp within 12 hours. They can also be viewed on our app.

    The normal level for the CA-125 test is <35 U/mL.

    One can expect a quick turnaround time for the CA-125 test with Orange Health Labs. The test report is typically delivered within 12 after the sample is collected.

    The frequency of CA-125 testing depends on your specific health condition. For individuals undergoing treatment for ovarian cancer, the test is done regularly to monitor the effectiveness of therapy and check for recurrence. For those at high risk or with symptoms of ovarian cancer, additional testing may be recommended by your doctor based on the test results.

    The CA-125 test measures only one parameter: the level of Cancer Antigen 125 (CA-125) protein in the blood sample.

    The CA-125 test does not require fasting.

    Orange Health Labs offers the fastest Cancer Antigen 125 (CA-125) test in Bangalore, delivered to the comfort of your home without the need to visit a physical lab. Testing is available in various localities including but not limited to Adugodi, Banashankari, Bannerghatta, Basavanagudi, Bellandur, BTM Layout, Chamrajpet, Cottonpet, CV Raman Nagar, Domlur, Electronic City, Frazer Town, Giri Nagar, Hebbal, Hennur, Hosur, HSR Layout, Jakkur, Jalahalli, Jaya Nagar, Kadugodi, Kammanahalli, Kengeri, Koramangala, Mahalakshmi Layout, Madiwala, Magadi Road, Malleshwaram, Marathahalli, Mathikere, Mysore Road, Nagarbhavi, Nandhini Layout, Old Airport Road, Peenya, RT Nagar, Rajaji Nagar, Rajarajeshwari Nagar, Sadashivnagar, Sahakara Nagar, Sanjay Nagar, Sarjapur, Seshadripuram, Shanthi Nagar, Shivaji Nagar, Sri Nagar, Tyagarajnagar, Uttarahalli, Vasanth Nagar, Vidyaranyapura, Vijaya Nagar, Whitefield, Yelahanka, Yeshwantpur.

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    References

    1. CA-125 Blood Test (Ovarian Cancer) [Internet]. Medlineplus.gov. 2022 [cited 2024 Aug 2].  Available from:  http://medlineplus.gov
    2. CA-125 Blood Test: Results, Normal Range & What To Expect [Internet]. Cleveland Clinic. 2022 [cited 2024 Aug 2].  Available from:  https://my.clevelandclinic.org/health/diagnostics/17830-ca-125-blood-test
    3. Gandhi T, Zubair M, Bhatt H. Cancer Antigen 125 [Internet]. Nih.gov. StatPearls Publishing; 2024 [cited 2024 Aug 2].  Available from:  https://www.ncbi.nlm.nih.gov/books/NBK562245/