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CertifiedLabsWhat is a Complete Blood Count (CBC) with ESR Test?
The complete blood count (CBC) with erythrocyte sedimentation rate (ESR) involves a detailed evaluation of various blood cell parameters such as the size and quantity of different blood cells within a given volume. The CBC with an ESR is the most commonly performed test in a routine examination. The test involves collecting a blood sample to analyse red blood cells (RBCs), white blood cells, platelets, haemoglobin levels, and other parameters. The ESR component measures the rate at which red blood cells settle at the bottom of a test tube in one hour, indicating inflammation. Together, CBC and ESR tests help identify inflammatory conditions, autoimmune diseases, anaemia, infections, and certain cancers, providing a comprehensive view of a patient's blood health.
Test Parameters
The CBC with ESR test includes a variety of parameters that provide a comprehensive overview of your blood health and potential inflammatory conditions. Here is a breakdown of each parameter included in the test:
Red Blood Cells (RBC) Count
Measures the number of red blood cells in your blood, which are responsible for carrying oxygen.
Haemoglobin (Hb)
Indicates the amount of haemoglobin in your blood, reflecting its oxygen-carrying capacity.
Haematocrit (HCT)/ Packed Cell Volume (PCV)
Represents the percentage of your blood that is made up of red blood cells.
Mean Corpuscular Volume (MCV)
Calculate the average size of your red blood cells.
Mean Corpuscular Haemoglobin (MCH)
Measures the average amount of haemoglobin inside a single red blood cell.
Mean Corpuscular Haemoglobin Concentration (MCHC)
Indicates the concentration of haemoglobin in a given volume of red blood cells.
Red Cell Distribution Width (RDW) CV
Reflects the variation in the size of your red blood cells.
Mentzer Index
A ratio is used to differentiate between iron deficiency anaemia and thalassemia.
Sehgal Index
Another index used to assess and differentiate types of anaemia.
Total White Blood Cell Count (TC)
Measures the total number of white blood cells, which are key to your immune response.
Differential and Absolute Counts
Measures the proportions and exact numbers of the 5 types of WBCs:
Neutrophils, lymphocytes, monocytes, basophils, eosinophils
Neutrophil Lymphocyte Ratio (NLR)
The ratio of neutrophils to lymphocytes is used to assess the immune system and inflammation.
Platelet Count
Measures the number of platelets, which are essential for blood clotting.
Platelet Haematocrit (Plateletcrit)
Indicates the proportion of blood volume that is made up of platelets.
Mean Platelet Volume (MPV)
Reflects the average size of your platelets.
Erythrocyte Sedimentation Rate (ESR)
Measures the rate at which red blood cells settle at the bottom of a test tube, indicating the presence of inflammation.
Test Preparation
Prerequisites
There are no specific prerequisites for the test, and fasting is not required.
Best Time to Get Tested
The test can be done at any time during the day for your convenience.
Eligibility
This test is suitable for individuals of all ages needing a comprehensive health evaluation. It is recommended for those with symptoms such as fatigue, weakness, unexplained bruising, or signs of infection, and for monitoring existing conditions or during routine check-ups.
Caution before taking the test
Inform your healthcare provider about all medications and supplements you are taking, as some can affect test results.
Why Take This Test?
The test may be necessary for the following reasons:
Routine Health Exam: Provides insights into overall health during regular checkups.
Symptom Investigation: Helps identify underlying conditions causing symptoms like fever, weight loss, joint stiffness, night sweats, bruising, bleeding, or fatigue.
Monitoring Ongoing Conditions: Regularly monitors conditions like cancer or chronic kidney disease (CKD) to assess disease progression or treatment efficacy.
Diagnosing inflammatory conditions: ESR aids in diagnosing autoimmune diseases, infections, cancers, inflammatory arthritis, and blood disorders.
Evaluation of Treatment: Evaluates response to treatments such as chemotherapy, which can affect blood cell counts and immune function.
Pregnancy Monitoring: Monitor the health of pregnant individuals and their developing foetuses.
Test Results & Interpretation
Below are the normal ranges of various parameters included in the CBC with ESR test:
| Parameter | Biological Reference | Interpretation |
|---|---|---|
| Red Blood Cells (RBC) Count | 4.5-5.5 mill/mm³ | High levels are observed in anaemia, heart disease, or iron deficiency. Low levels are observed in dehydration, heart disease, or polycythemia. |
| Haemoglobin (Hb) | 13.0-17.0 g/dL | |
| Hematocrit (HCT)/ Packed Cell Volume (PCV) | 40-50% | |
| Mean Corpuscular Volume (MCV) | 83-101fL | |
| Mean Corpuscular Haemoglobin (MCH) | 27-32pg | |
| Mean Corpuscular Haemoglobin Concentration (MCHC) | 31.5-34.5g/dL | |
| Red Cell Distribution Width (RDW) CV | 11.6-14.0% | |
| Mentzer Index | Beta Thalassemia trait: < 14 Iron deficiency anaemia: >= 14 | A high index indicates iron deficiency. A low index indicates thalassemia. |
| Sehgal Index | Beta Thalassemia trait: < 972 Iron deficiency anaemia: >= 972 | |
| Total White Blood Cell Count (TC) | 4000-10000 cells/mm³ | High levels may indicate an autoimmune disorder, bone marrow disorder, or cancer. Low levels may occur in infection, inflammation, or a reaction to medication. |
| Differential Count | ||
| Neutrophils | 40-80% | |
| Lymphocytes | 20-40% | |
| Monocytes | 2-10% | |
| Eosinophils | 1-6% | |
| Basophils | 0-2% | |
| Absolute Neutrophil Count (ANC) | 2000-7000/mm³ | |
| Absolute Lymphocyte Count (ALC) | 10000-3000/mm³ | |
| Absolute Monocyte Count (AMC) | 200-1000/mm³ | |
| Absolute Eosinophil Count (AEC) | 20-500/mm³ | |
| Absolute Basophil Count (ABC) | 0-100/mm³ | |
| Neutrophil Lymphocyte Ratio (NLR) | 1.0-3.0 | High NLR suggests inflammation 6 |
| Platelet Count | 150-450 (10^3/μL) | Platelets rise in autoimmune disorders or certain infections. Low platelet count is observed in inflammatory conditions or bone marrow disorders. |
| Platelet Hematocrit | 0.20-0.50% | |
| Mean Platelet Volume (MPV) | 7-13dL | |
| Erythrocyte Sedimentation Rate (ESR) | 01-10mm/h | ESR is high in anaemia, Cancers such as lymphoma or multiple myeloma, thyroid disease, pregnancy, and autoimmune disorders. ESR is low in Polycythaemia, sickle cell anaemia, congestive heart failure, Leukaemia, Low plasma protein |
FAQs
The CBC with ESR is used to evaluate your overall health and detect a variety of disorders, including anaemia, infection, and inflammation. The CBC measures different components of your blood including ESR.
No, fasting is not required for a CBC with ESR test.
Yes, Orange Health Labs offers swift sample collection for a blood test with ESR.
Orange Health Labs offers swift sample collection for the CBC with ESR test. You can expect your test reports within 6 hours of sample collection.
The frequency of testing depends on your medical condition and your doctor's recommendation.
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Frequently Asked Questions
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Why should you choose Orange Health Labs over other pathology labs?
Orange Health Labs stands out as the fastest diagnostic lab in town. From rapid at-home testing to expert eMedics, we blend cutting-edge diagnostics with comfort. With trusted certifications for our lab, we're your trusted path to accurate results. Experience health on your terms!Q2
How does home collection within 60 minutes work?
We guarantee home pathology services within just 60 minutes from order placement in Bangalore, Delhi, Gurugram, Noida, Hyderabad, Faridabad, and Mumbai. Our skilled, vaccinated eMedics, following your chosen schedule, will arrive at your door. Your sample will be carefully handled, maintained at the right temperature, and transported to our certified labs. And rest assured, the results will reach you with even greater speed!Q3
How are reports delivered?
You will receive your reports via WhatsApp within 6 hours for most tests with our diagnostic laboratory. Additionally, you can access and view the reports on our app at any time.Q4
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You can cancel the booking from the Order Tracking Page on our app. Also, you can reach out to customer support via WhatsApp at 9008111144. We're here to help, and we'll get back to you in a flash!Q6