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CertifiedLabsWhat is Tissue Transglutaminase antibody IgA Test?
The Anti-Tissue Transglutaminase (tTG-IgA) blood test is a highly accurate medical test commonly used to diagnose coeliac disease and dermatitis herpetiformis. Coeliac disease is an autoimmune condition triggered by the consumption of gluten, a protein found in grains such as wheat, barley, rye, and oats. When gluten is consumed, the immune system produces antibodies that target tissue transglutaminase (tTG), an enzyme necessary for proper intestinal function, causing inflammation and intestinal damage.
This test is often advised for individuals showing symptoms like gastrointestinal discomfort, unexplained fatigue, or malabsorption. It is particularly useful for those with a genetic predisposition to coeliac disease, thyroid problems, type 1 diabetes, or other autoimmune conditions.
Residents of Pune concerned about gluten sensitivity or the possibility of coeliac disease can now book the Anti Tissue Transglutaminase test at home.
Tissue Transglutaminase antibody IgA Test Parameters
The tTG-IgA test helps detect antibodies called IgA anti-tissue transglutaminase, which are strong indicators of coeliac disease.
These antibodies are produced when the immune system mistakenly targets tissue transglutaminase (tTG) after gluten is eaten. With over 90% accuracy, it is widely trusted for diagnosing coeliac disease and monitoring progress.
These antibodies can appear early in the disease, often before symptoms like fatigue or stomach pain are noticed. In most untreated cases, both IgA anti-tTG and IgA anti-endomysial antibodies are present. Adopting a gluten-free diet reduces these antibody levels, often making them undetectable. This test is also valuable for checking recovery and dietary compliance.
Tissue Transglutaminase antibody IgA Test Preparation
Here is what you need to know before taking the IgA anti-tTG test:
Prerequisites: There is no need to fast before the Anti Tissue Transglutaminase test.
Best Time to Get Tested: The Anti Tissue Transglutaminase test can be performed at any time of the day, based on your convenience.
Who Should Get an Anti-Tissue Transglutaminase Test?: This test is suitable for individuals experiencing symptoms like long-lasting diarrhea, abdominal discomfort, stunted growth, or unexplained skin issues. It’s also useful for those with a family history of coeliac disease or conditions like thyroid problems or type 1 diabetes.
Cautions Before Taking an Anti-Tissue Transglutaminase Test: Ensure you’re consuming gluten before the test, as avoiding it may lower antibody levels and affect the accuracy of results.
Why Take the Tissue Transglutaminase antibody IgA Test?
The Anti-Tissue Transglutaminase test can be considered if you have:
● Have symptoms of coeliac disease , such as:
o Constipation
o Vomiting
o Chronic diarrhoea
o Abdominal pain
o Skin rashes
o Poor growth
o Bloating
● Have autoimmune disorders , like type 1 diabetes or thyroid problems, which are associated with coeliac disease.
● Have a family history of coeliac disease , which significantly increases your chances of being affected.
FAQs on Tissue Transglutaminase antibody IgA Test in Pune
The cost of the Anti-Tissue Transglutaminase test in Pune is ₹1309, including complimentary home sample collection within 60 minutes of booking. Results are available within 106 hours.
Yes, Orange Health Labs offers hassle-free home collection services for the Anti-Tissue Transglutaminase test. A skilled professional will arrive within 60 minutes of your booking to collect the sample.
This test is used to detect IgA antibodies against tissue transglutaminase, assisting in the diagnosis of coeliac disease and gluten intolerance. It is also helpful for monitoring disease activity and assessing the effectiveness of a gluten-free diet.
Fasting is not required for the Anti-Tissue Transglutaminase test.
To book an Anti-Tissue Transglutaminase test with Orange Health Labs, follow these steps:
● Step 1: Search : Look for the Anti-Tissue Transglutaminase Test on the Orange Health Labs platform.
● Step 2: Provide Information : Add your personal details, choose a location, and select a preferred time slot.
● Step 3: Sample Collection : A trained eMedic will visit your home or office to take the sample.
● Step 4: Laboratory Analysis : Your sample will be processed in a NABL-accredited, ICMR-approved laboratory.
● Step 5: Results Delivered : Receive your results digitally through email or WhatsApp within 106 hours.
Normal results typically show no IgA anti-tTG antibodies (negative). Elevated levels often signal coeliac disease or gluten sensitivity.
In Pune, results for the Anti-Tissue Transglutaminase test are shared within 106 hours after the collection of your sample.
Doctors generally recommend the test for initial diagnosis and to track progress in people adhering to a gluten-free diet. Testing frequency varies by individual health needs.
The test detects IgA anti-tTG antibodies, a reliable marker for identifying coeliac disease and gluten intolerance.
Orange Health Labs provides home collection services for the Anti-Tissue Transglutaminase test in areas around Pune like Colaba, Nariman Point, Marine Drive, Malabar Hill, Churchgate, Worli, Dadar, Parel, Byculla, Bandra, Andheri, Juhu, Ghatkopar, Powai, Chembur, Vashi, Belapur, Santacruz, Khar, Versova, Lokhandwala, Goregaon, Borivali, Kandivali, Mulund, Bhandup, Kurla.
Payment & Refund Policy
- We do not accept cash payments
- All modes of online payment are accepted
- Refunds will be credited back to the source of payment within 5-7 working days of order cancellation.
References
- Blood Test: Tissue Transglutaminase IgA (tTg-IgA) (for Parents). Available from: https://kidshealth.org/en/parents/test-ttg.html
- Tissue Transglutaminase Antibody (TTG) - South Tees Hospitals NHS Foundation Trust. Available from: https://www.southtees.nhs.uk/services/pathology/tests/tissue-transglutaminase-antibody-ttg/
- Pathology Handbook. Available from: https://www.pathology.med.umich.edu/handbook/#/details/1217