The Gliadin Deamidated Peptide Antibody IgG test detects specific antibodies in the blood that may indicate coeliac disease or gluten sensitivity. Coeliac disease is an autoimmune disorder in which gluten—found in grains like wheat, rye, and barley—triggers an immune attack on the small intestine. Over time, this leads to damage to the intestinal villi, impairing nutrient absorption and causing symptoms such as stomach pain, fatigue, anaemia, weak bones, and unintended weight loss.

If the IgG test result is positive, additional testing, such as a biopsy of the small intestine, may be necessary for confirmation. Coeliac disease can appear at any age, though it is most diagnosed in infants (8–12 months) and adults (40–60 years). Because symptoms can be mild or unclear, many people remain undiagnosed. Those with a family history of the disease or other autoimmune conditions should consider testing, even if they feel healthy.

For individuals in Pune, the Gliadin Deamidated Peptide Antibody IgG test is available as an at-home testing option for gluten-related immune responses.

Preparing for the Gliadin Deamidated Peptide Antibody IgG test:

• Prerequisites: Fasting is not necessary for the test.

• Best Time to Get Tested: The test offers flexibility and can be performed at any time throughout the day.

• Who Should Get a Gliadin Deamidated Peptide Antibody IgG Test? This test is recommended for individuals experiencing digestive symptoms, unexplained weight loss, nutrient deficiencies, autoimmune disorders, or classic signs of coeliac disease, including diarrhoea, bloating, fatigue, and skin rashes.

• Cautions Before Taking a Gliadin Deamidated Peptide Antibody IgG Test: No special pre-test preparations are needed. However, maintaining a gluten-containing diet is important. Stopping gluten intake weeks before the test may reduce antibody levels, potentially leading to a false-negative result.

The Gliadin Deamidated Peptide Antibody IgG test is recommended if you show symptoms of coeliac disease, including:

• Digestive Symptoms:

• • Diarrhoea (frequent)

  • Gas and constipation

  • Bloating and stomach pain

  • Stools that are pale, greasy, or have an unpleasant smell.

• Other Physical Indicators:

• • Unexplained weight loss

  • Mouth sores

  • Tingling or numbness in hands and feet

• Mood and Skin Symptoms:

• • Fatigue and feeling tired constantly.

  • Anxiety or depression

  • Itchy skin rashes

Testing may still be necessary even without these symptoms, especially if your body struggles to absorb nutrients such as iron, folate, vitamin B12, calcium, or vitamin D.

Higher-risk groups include those with type 1 diabetes, Down syndrome, or other genetic disorders. Additionally, consider testing if you:

• Have frequent headaches.

• Face difficulties with growth (in children)

• Experience fertility issues.