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    What Is the Angiotensin Converting Enzyme (ACE) Test?

    The Angiotensin Converting Enzyme (ACE) test is designed to measure the amount of a particular protein called angiotensin-converting enzyme in your blood. ACE is produced by the cells that line your blood vessels and plays a crucial role in controlling blood pressure. However, when ACE levels are elevated, it could indicate a condition called sarcoidosis, where small clusters of immune cells, or granulomas, form in various organs, particularly the lungs. These clusters can cause health issues. Elevated ACE levels are often found in people with active sarcoidosis, with 50% to 80% of those affected showing higher levels. Doctors may recommend the ACE test if they suspect sarcoidosis is causing symptoms like a chronic cough, breathing difficulties, or joint pain.

    In addition to sarcoidosis, elevated ACE levels can be associated with various other health conditions, such as infections like tuberculosis and exposure to certain chemicals. If high ACE levels are detected, further tests may be necessary to pinpoint the exact cause.

    Although ACE is naturally present in the body, medications known as ACE inhibitors are used to lower blood pressure by blocking its action. These drugs may influence the test results.

    If you’re in Noida and experiencing symptoms like a persistent cough, shortness of breath, or joint pain, you may wish to book an Angiotensin Converting Enzyme test in Noida to help diagnose possible inflammatory conditions like sarcoidosis.

    Angiotensin Converting Enzyme (ACE) Test Parameters

    The Angiotensin Converting Enzyme (ACE) test measures one key parameter: the levels of angiotensin-converting enzyme in the blood.

    ACE is a special protein that helps regulate blood pressure by converting a substance called angiotensin I into angiotensin II. This process causes blood vessels to narrow, resulting in an increase in blood pressure. Although most ACE is found in the lungs, it is also present in other areas of the body. Individuals under 20 typically have higher ACE levels, but as you age, these levels tend to decrease and stabilise.

    ACE is also produced by specific cells in response to infection or inflammation. These cells are part of the immune system and create small clusters known as granulomas. Granulomas are often observed in conditions like sarcoidosis, where they primarily affect the lungs and other organs.

    Angiotensin Converting Enzyme (ACE) Test Preparation

    When arranging an Angiotensin Converting Enzyme test, keep the following in mind:

    Prerequisites Fasting is not required for the Angiotensin Converting Enzyme test.

    Best Time to Get Tested You can schedule the test at any time of the day, depending on your convenience.

    Who Should Have the Angiotensin Converting Enzyme (ACE) Test? This test is typically recommended for individuals experiencing symptoms such as unexplained shortness of breath, persistent cough, joint pain, or unexplained weight changes, which may suggest conditions like sarcoidosis or other related health issues.

    Precautions Before the Angiotensin Converting Enzyme (ACE) Test No special precautions are needed before undergoing the Angiotensin Converting Enzyme test.

    Why Take the Angiotensin Converting Enzyme (ACE) Test?

    The ACE test is used to detect sarcoidosis or other conditions that can lead to the formation of granulomas. Granulomas can develop in various organs, resulting in a range of symptoms. If you experience any of the following, the ACE test might be beneficial:

    • Persistent cough, breathing difficulties, or wheezing

    • Extreme fatigue

    • Unexplained weight loss or lack of appetite

    • Chest pain

    • Joint stiffness or soreness

    • Vision problems

    • Dry mouth

    • Headaches

    • Unusual skin changes, such as rashes, sores, or hardened spots

    • Fever

    The test is particularly useful for individuals aged 20 to 40, as sarcoidosis is most common in this age group. The ACE test can also help differentiate between sarcoidosis and other granuloma-causing conditions, such as infections.

    If someone has been diagnosed with sarcoidosis and initially had elevated ACE levels, repeating the test can assist in monitoring disease progression. Tracking ACE levels can also be helpful in assessing the effectiveness of treatment.

    FAQs on the Angiotensin Converting Enzyme (ACE) Test in Noida

    The price of the Angiotensin Converting Enzyme test in Noida is ₹1232. This includes the convenience of home sample collection, which will take place within 60 minutes of confirming your booking. Results will be available within 84 hours after the sample has been collected.

    Yes, the Angiotensin Converting Enzyme test at home collects your sample from home when booked through Orange Health Labs. A trained eMedic will visit your location to collect the sample within 60 minutes after confirming your booking, depending on slot availability.

    The Angiotensin Converting Enzyme test checks the ACE levels in your blood, helping to diagnose conditions such as sarcoidosis, lung diseases, and liver issues. High ACE levels are commonly found in medical conditions that cause inflammation in the body.

    Generally, fasting is not required for an ACE test. However, it’s recommended to adhere to any instructions given by your doctor.

    To schedule your Angiotensin Converting Enzyme test, simply follow these steps: • Find the test: Visit the Orange Health website and locate the Angiotensin Converting Enzyme test. • Confirm the appointment: Fill in your details, pick a time that suits you, and confirm your booking. • Sample collection: Once your booking is confirmed, a qualified eMedic will be sent to collect the sample from your location. • Laboratory processing: Your blood sample will be processed at an ICMR-approved and NABL-accredited laboratory. • Results: You’ll receive your results via email or WhatsApp within 84 hours of sample collection, and they will also be available on the Orange Health app.

    ACE levels in the blood are typically between 12 and 68 units per litre (u/L).

    After confirming your booking for the Angiotensin Converting Enzyme test, an eMedic will collect the sample within 60 minutes. You can expect to receive the results within 84 hours following the sample collection.

    How often you need the Angiotensin Converting Enzyme test depends on your health and personal factors. Speak with your doctor to determine the appropriate schedule.

    This test for Angiotensin Converting Enzyme evaluates a single factor – the concentration of angiotensin-converting enzyme in your blood.

    Orange Health offers home sample collection for the Angiotensin Converting Enzyme test in multiple locations throughout Noida, including areas such as DLF Phase 1, DLF Phase 2, DLF Phase 3, DLF Phase 4, DLF Phase 5, Sector 14, Sector 15, Sector 21, Sector 22, Sector 23, Sector 24, Sector 29, Sector 31, Sector 40, Sector 42, Sector 43, Sector 45, Sector 46, Sector 50, Sector 51, Sector 52, Sector 53, Sector 54, Sector 55, Sector 56.

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    References

    1. Angiotensin converting enzyme (ACE) | Pathology Tests Explained [Internet].  Available from:  https://www.pathologytestsexplained.org.au/ptests-pro.php?q=ACE+%28Angiotensin+converting+enzyme%29
    2. Angiotensin Converting Enzyme (Blood) [Internet].  Available from:  https://www.urmc.rochester.edu/encyclopedia/content?ContentTypeID=167&ContentID=angiotensin_converting_enzyme_blood
    3. Kahkouee S, Samadi K, Alai A, Abedini A, Rezaiian L. Serum ACE Level in Sarcoidosis Patients with Typical and Atypical HRCT Manifestation. Polish Journal of Radiology [Internet].  Available from:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036380/