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    Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA2924262510% off
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    What Is Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test?

    The Anti Neutrophil Cytoplasmic Antibody (ANCA) test is a blood test that checks for certain proteins made by the immune system. These proteins usually help fight infections but, in some cases, they erroneously target healthy monocytes and neutrophils.

    This test is mainly used to diagnose ANCA-associated vasculitis, a condition that causes inflammation of the blood vessels. When this happens, blood vessels may become narrow, weak, or blocked, which can harm important organs like the kidneys, lungs, skin, and eyes. The first symptoms of vasculitis often include fatigue, fever, body ache and weight loss. If not treated in time, vasculitis may lead to severe organ damage.

    The two main proteins linked to ANCA-associated vasculitis are:

    • Myeloperoxidase (MPO): Mostly found in microscopic polyangiitis (MPA), which affects small blood vessels.

    • Proteinase 3 (PR3): Commonly seen in granulomatosis with polyangiitis (GPA), which mainly affects the lungs and sinuses.

    Other tests, including PR3 ANCA, full blood counts, inflammation markers, and kidney function tests may be needed to confirm the diagnosis and monitor treatment.

    If you're in Noida, you can opt for the Anti Neutrophil Cytoplasmic Antibody (ANCA) test at home, which allows for easy sample collection and quick delivery of results.

    Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test Parameters

    The Anti Neutrophil Cytoplasmic Antibody (ANCA) test is a blood test that looks for autoantibodies, particularly PR3 and MPO. These are immune system proteins that sometimes attack healthy cells instead of attacking harmful microorganisms.

    The autoantibodies detected in this test target two proteins:

    cANCA (cytoplasmic ANCA)

    Attacks PR3, a protein involved in blood cell production and cell death.

    pANCA (perinuclear ANCA)

    Targets MPO, a key protein that helps fight infections.

    Neutrophils are activated in the presence of ANCAs and release chemicals that cause inflammation and damage blood vessels. This process can harm organs such as the kidneys, lungs, and skin. As neutrophils pass through blood vessel walls, they release even more chemicals, worsening inflammation and tissue damage.

    Although ANCA, PR3, and MPO levels can vary, some people continue producing these autoantibodies (they may not be detectable on tests). A positive ANCA test is often linked to vasculitis but can also be found in conditions such as infections (e.g., respiratory infections and endocarditis), inflammatory bowel disease, and rheumatoid arthritis. Some medications can also lead to a positive test result.

    Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test Preparation

    If you’re getting ready for the Anti Neutrophil Cytoplasmic Antibody (ANCA) test at home, here’s what to keep in mind:

    • Prerequisites: No preparation is needed, and fasting is not required before the test.

    • Best Time to Get Tested : You can take the ANCA test at any time of the day.

    • Who Should Get an Anti Neutrophil Cytoplasmic Antibody (ANCA) Test? If you have fever, persistent tiredness, joint pain, weight loss, or symptoms affecting your lungs, kidneys, nervous system or skin, this test can help determine if autoimmune vasculitis is present.

    • Cautions Before Taking an Anti Neutrophil Cytoplasmic Antibody (ANCA) Test : There are no special precautions to follow before the ANCA test.

    Why Take the Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test?

    The Anti Neutrophil Cytoplasmic Antibody (ANCA) test is useful if you have:

    • Unexplained symptoms like constant fatigue, fever, weight loss, muscle or joint pain, or night sweats.

    • Symptoms related to specific organs:

      • Eyes, ears, and nose: Blurred vision, frequent sinus infections, or hearing loss.

      • Skin: Itching, unusual rashes, or bruising.

      • Lungs: Coughing up blood or difficulty breathing.

      • Kidneys: Blood or protein found in urine tests.

      • Nervous system: Shooting pain, numbness, or tingling.

      • Stomach and intestines: Abdominal pain, diarrhoea, or vomiting blood.

    • Suspected autoimmune vasculitis, such as GPA or MPA.

    • Signs of inflammatory bowel disease, including diarrhoea, blood in the stool, or a long-lasting fever.

    • Ongoing monitoring of known autoimmune vasculitis through regular tests.

    Early detection with the ANCA test helps manage symptoms effectively and prevents serious complications.

    FAQs on Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test in Noida

    In Noida, the Anti Neutrophil Cytoplasmic Antibody (ANCA) test is available for ₹2625. The test includes home sample collection, which takes place within 60 minutes of booking. With Orange Health Labs, your test results will be ready within 122 hours after sample collection.

    Yes, Orange Health Labs offers stress-free home sample collection for the Anti Neutrophil Cytoplasmic Antibody (ANCA) test. A certified eMedic professional will arrive at your doorstep within 60 minutes after booking to collect your blood sample.

    The Anti Neutrophil Cytoplasmic Antibody (ANCA) test helps in the diagnosis of autoimmune conditions such as vasculitis. It detects certain autoantibodies in the blood that may cause inflammation and affect blood vessels and organs.

    No, you can take the Anti Neutrophil Cytoplasmic Antibody (ANCA) test without fasting.

    Arranging for the Anti Neutrophil Cytoplasmic Antibody (ANCA) test with Orange Health Labs is straightforward, as follows:

    • Search the Test: Search for "Anti Neutrophil Cytoplasmic Antibody (ANCA) test" and select Orange Health Labs.

    • Confirm your Booking: Enter your details, select your location, and pick a suitable time for sample collection.

    • Sample Collection: A trained eMedic professional will visit your home or location for sample collection.

    • Analysis & Results: The sample will be analysed at our NABL-accredited, ICMR-approved laboratory, and the results will be sent to you via email or WhatsApp within 122 hours.

    A normal ANCA test result is negative, meaning no p-ANCA or c-ANCA autoantibodies are found, making autoimmune vasculitis unlikely. A positive result indicates elevated levels and should be followed up with additional tests to identify possible autoimmune conditions.

    After your sample is collected, the results of the Anti Neutrophil Cytoplasmic Antibody (ANCA) test will be available within 122 hours.

    Your doctor will determine how frequently you need the Anti Neutrophil Cytoplasmic Antibody (ANCA) test based on your specific medical condition.

    The ANCA test checks for antibodies, which include PR3 and MPO antibodies.

    Multiple locations in Noida offer the Anti Neutrophil Cytoplasmic Antibody (ANCA) test, including but not limited to Sector 1, Sector 15, Sector 18, Sector 26, Sector 37, Sector 50, Sector 62, Sector 76, Sector 93, Sector 100, Sector 104, Sector 110, Sector 120, Sector 128, Sector 137, Sector 150, Sector 168, Sector 71, Sector 63, Sector 22, Sector 41, Sector 108, Sector 47, Sector 121, Sector 45.

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    References

    1. Antineutrophil Cytoplasmic Antibodies (ANCA) Test: MedlinePlus Medical Test.  Available from:  https://medlineplus.gov/lab-tests/antineutrophil-cytoplasmic-antibodies-anca-test/
    2. Antineutrophil Cytoplasmic Antibodies (ANCA) Test: What It Is. 3. Antineutrophil cytoplasmic antibodies (ANCA) | Pathology Tests Explained. 4. Khalid N, Aeddula NR. Antinuclear Cytoplasmic Antibody [Internet]. PubMed. Treasure Island (FL). 5. The value of anti-neutrophil cytoplasmic antibodies (ANCA) testing for the diagnosis of ANCA-associated vasculitis, a systematic review and meta-analysis.  Available from:  https://my.clevelandclinic.org/health/diagnostics/22512-anca-test