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    Anti Smooth Muscle antibody (Anti-SMA) (IFA)2626200024% off
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    What is Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test?

    The Anti Smooth Muscle Antibody (ASMA) test is a blood test that identifies smooth muscle antibodies (SMAs), which are autoantibodies mistakenly produced by the immune system. These antibodies attack healthy liver cells, leading to inflammation and tissue damage. This test plays a crucial role in diagnosing autoimmune hepatitis (AIH), a chronic condition where the immune system incorrectly targets liver tissue.

    In a normal immune response, the body fights off harmful pathogens like bacteria and viruses. However, in autoimmune diseases such as AIH, the immune system mistakenly generates autoantibodies like ASMAs that attack its tissues. If not treated promptly, AIH can cause severe complications, including liver cirrhosis. Treatment usually involves immunosuppressive medications to control the immune response and prevent further liver damage.

    There are two main types of AIH:

    • Type 1 AIH, the more prevalent form, affects both adults and children, with a higher occurrence in women.

    • Type 2 AIH, which is less common, mostly affects young girls and is linked to other antibodies like LKM-1.

    To confirm an AIH diagnosis, the ASMA test is often conducted alongside other autoantibody tests, such as ANA and LKM-1.

    For those in Noida, this test is available with home sample collection and fast result processing, making it convenient and hassle-free.

    Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test Parameters

    The ASMA test checks for anti-smooth muscle antibodies in the blood, which mistakenly attack smooth muscle proteins found in hollow organs such as the stomach, intestines, and blood vessels. Since these proteins are also present in liver cells, an elevated ASMA level is often a sign of liver disease, particularly autoimmune hepatitis (AIH).

    This test helps determine if the immune system is attacking the liver by mistake. To ensure an accurate diagnosis, it is typically performed along with other autoantibody tests, such as ANA and LKM-1 tests.

    Different testing methods are available to assess ASMA levels, helping identify the specific antibodies present and their concentration. Since its discovery in liver disease patients, ASMA testing has been a crucial tool in diagnosing and managing AIH. Early detection allows for timely treatment, reducing the likelihood of liver damage, cirrhosis, and failure. If ASMA is found, immune-suppressing treatments can help protect the liver and slow disease progression.

    Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test Preparation

    Here’s what you need to know before undergoing the Anti-Smooth Muscle Antibody (ASMA) test at home:

    • Prerequisites :

    No fasting or special steps are required before the test.

    • Best Time to Get Tested :

    The test can be done at any hour of the day.

    • Who Should Get an Anti Smooth Muscle Antibody Test? :

    Individuals with liver disease symptoms like yellowing skin (jaundice), ongoing fatigue, or abdominal pain, as well as those with irregular liver test results, may need this test to help diagnose autoimmune hepatitis.

    • Cautions Before Taking an Anti Smooth Muscle Antibody Test :

    No special precautions are needed before the test.

    Why Take the Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test?

    If you have symptoms of liver dysfunction, an Anti-Smooth Muscle Antibody (ASMA) test may be recommended. Possible signs include:

    • Persistent fatigue and weakness

    • Jaundice (yellowing of the skin and eyes)

    • Unexplained nausea or poor appetite

    • Abdominal discomfort or pain

    • Changes in urine (dark-coloured) and stool (light-coloured)

    • Joint stiffness or aching

    • Skin conditions such as acne, rashes, vitiligo, or psoriasis

    Since autoimmune hepatitis (AIH) can develop without obvious symptoms, abnormal liver function test results may indicate the need for an ASMA test. If ASMA is detected, further evaluation, such as a liver biopsy, may be needed to determine the extent of liver damage.

    FAQs on Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test in Noida

    The price for this test in Noida is ₹2000. The fee covers home sample collection, where a technician will reach your location within 60 minutes of booking. Results will be available within 110 hours after sample collection.

    Yes, you can book a home sample collection for this test. A trained healthcare professional will visit you within 60 minutes to collect the sample.

    This test helps in detecting autoimmune hepatitis (AIH) by identifying antibodies that mistakenly attack smooth muscle proteins in the liver. It also assists in evaluating liver function and determining whether further tests, such as a biopsy, are necessary.

    No, fasting is not required. You can take the test at any time.

    Booking your Anti-Smooth Muscle Antibody test with Orange Health Labs in Noida is quick and easy:

    • Step 1: Find the test by searching for "Anti-Smooth Muscle Antibody test" and selecting Orange Health Labs.

    • Step 2: Provide necessary details like your name, address, and preferred time for sample collection.

    • Step 3: A qualified eMedic expert will visit your location to collect the blood sample.

    • Step 4: Your sample will be tested in a NABL-certified, ICMR-approved laboratory, and results will be delivered via email or WhatsApp within 110 hours.

    A negative result is the normal finding, indicating no presence of autoantibodies. A positive test may point to liver-related autoimmune conditions like autoimmune hepatitis.

    Test results are typically available within 110 hours after sample collection.

    The frequency of this test depends on your health status and your physician’s recommendations.

    It assesses autoantibodies targeting smooth muscle proteins, which help diagnose certain autoimmune liver conditions.

    The test is offered in multiple localities of Noida such as Sector 1, Sector 15, Sector 18, Sector 26, Sector 37, Sector 50, Sector 62, Sector 76, Sector 93, Sector 100, Sector 104, Sector 110, Sector 120, Sector 128, Sector 137, Sector 150, Sector 168, Sector 71, Sector 63, Sector 22, Sector 41, Sector 108, Sector 47, Sector 121, Sector 45.

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    References

    1. Smooth Muscle Antibody (SMA) Test: MedlinePlus Medical Test. 2. Anti-smooth muscle antibody - UF Health.  Available from:  https://medlineplus.gov/lab-tests/smooth-muscle-antibody-sma-test/
    2. Zhang WC, Zhao FR, Chen J, Chen WX. Meta-Analysis: Diagnostic Accuracy of Antinuclear Antibodies, Smooth Muscle Antibodies and Antibodies to a Soluble Liver Antigen/Liver Pancreas in Autoimmune Hepatitis.  Available from:  https://pmc.ncbi.nlm.nih.gov/articles/PMC3961308/#s4