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    Anti Nuclear Antibody (ANA) (IFA)2507180028% off
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    What is the Anti Nuclear Antibody (ANA) (IFA) Test?

    The ANA IFA test evaluates two primary elements: titre value and fluorescent pattern.

    Titre Value: This component measures the concentration of antinuclear antibodies (ANAs) in the blood. To determine the titre, the blood is diluted progressively until no antibodies are detectable. The highest dilution level at which antibodies are still observed is noted as the titre. A higher titre indicates more antibodies, increasing the likelihood of an autoimmune disease.

    Pattern: The test also investigates how these antibodies bind to cell components using a fluorescent dye that glows under a microscope. This glowing pattern helps identify specific autoimmune disorders like lupus, rheumatoid arthritis, or Sjögren’s syndrome. By evaluating these patterns, doctors can determine whether further testing is necessary to identify specific antibodies.

    The ANA test uses the Indirect Immunofluorescence (IFA) method, which helps in visualizing these patterns and offers crucial information for diagnosing autoimmune conditions.

    Anti Nuclear Antibody (ANA) (IFA) Test Parameters

    The ANA IFA test evaluates two key aspects: the titre value and the fluorescent pattern.

    Titre Value: This measures the concentration of antinuclear antibodies (ANAs) in your blood. To determine this, the blood sample is systematically diluted until the antibodies are no longer visible. The highest dilution level where antibodies remain detectable is noted as the titre. A higher titre indicates a greater quantity of antibodies and a higher likelihood of an autoimmune disorder. Pattern: The test also examines how these antibodies bind to various parts of the cell using a special fluorescent dye, which glows under a microscope. This glowing pattern helps doctors identify specific autoimmune diseases like lupus, rheumatoid arthritis, or Sjögren’s syndrome. By analyzing these patterns, doctors can decide if further testing is needed to determine the presence of specific antibodies.

    The ANA test employs the Indirect Immunofluorescence (IFA) technique, which helps visualize the distinct patterns of these antibodies and provides critical insights for diagnosing autoimmune conditions.

    Anti Nuclear Antibody (ANA) (IFA) Test Preparation

    Before booking an ANA test at home, keep these points in mind:

    • Prerequisites

    Fasting is not a requirement for the ANA test.

    • Best Time to Get Tested

    The ANA test can be scheduled at any hour of the day.

    • Who Should Get an ANA Profile Test?

    You may need an ANA test if your doctor suspects an autoimmune condition. Symptoms prompting this test include chronic fatigue, fever, skin rashes or changes, joint discomfort, stiffness, swelling, or muscle pain. The test detects antibodies in your blood, which helps in diagnosing autoimmune diseases.

    • Cautions Before Taking the ANA Profile Test

    Typically, there are no special precautions or preparations necessary for the ANA test.

    Why Take the Anti Nuclear Antibody (ANA) (IFA) Test?

    The ANA test helps detect autoimmune disorders by finding specific antibodies in your blood. It is useful in diagnosing:

    • Scleroderma: A rare condition involving skin and organ issues.

    • Addison Disease: Affects adrenal glands, leading to fatigue and weakness.

    • Systemic Lupus Erythematosus (SLE): A multi-system disease impacting joints, skin, and organs.

    • Rheumatoid Arthritis: A joint disorder characterized by pain and swelling.

    • Autoimmune Hepatitis: Involves inflammation of the liver.

    • Sjögren's Syndrome: Affects glands that produce tears and saliva.

    Doctors may order this test if you experience symptoms such as joint pain, fever, persistent fatigue, rashes, or muscle pain to determine whether an autoimmune disease could be the cause.

    Anti Nuclear Antibody (ANA) (IFA) Test Results & Interpretation

    The ANA test helps in identifying autoimmune conditions by detecting antibodies that attack the nucleus of cells.

    • Positive Results: The presence of antibodies suggests a potential autoimmune disease, viral infection, or other conditions.

    • Weakly Positive Results: It’s advisable to retest in 6-8 weeks for better evaluation if the result is weakly positive.

    • Negative Results: No antibodies are detected, reducing the likelihood of an autoimmune disorder but not eliminating the possibility.

    Different patterns of antibodies found in a positive ANA test can provide further insight into specific autoimmune diseases:

    • Nuclear Dot Pattern: Points to liver disease and rheumatic conditions, targeting specific nuclear proteins.

    • Homogeneous Pattern: Indicates lupus, showing antibodies against DNA and histones.

    • Speckled Pattern: Associated with lupus, Sjögren's syndrome, or rheumatoid arthritis, targeting various nuclear proteins.

    • Dense Fine Speckled (DFS): Found in some healthy individuals and inflammatory conditions.

    • Nucleolus Pattern: Suggests involvement in muscle and skin diseases.

    • Centromere Pattern: Linked to specific forms of scleroderma, related to proteins involved in cell division.

    • Nuclear Membrane Pattern: Seen in chronic fatigue syndrome and collagen disorders.

    • Cytoplasmic Patterns: Associated with liver conditions, Sjögren's syndrome, and muscle disorders.

    A positive ANA result is not definitive for an autoimmune diagnosis. Further testing and clinical correlation are needed to confirm the specific condition.

    FAQs on Anti Nuclear Antibody (ANA) (IFA) Test in Mumbai

    The price of the ANA test in Mumbai is ₹ 1800. This price is inclusive of home sample collection within 60 minutes after booking, with reports available in 121 hours.

    Yes, one can expect convenient sample collection for undergoing ANA tests at home in Mumbai. A professional eMedic will collect your blood sample at your convenience within 60 minutes after booking, subject to availability.

    The ANA test is used to identify the antibodies that have targeted the body’s cells. In this way, it helps diagnose autoimmune diseases like rheumatoid arthritis and lupus. A positive result may indicate an autoimmune condition.

    No, the ANA profile test does not require fasting.

    To book an ANA Profile test through Orange Health Labs, follow these steps:

    • Locate the Test: Search for the Antinuclear Antibody/ANA test on our platform, available in Mumbai or for home collection, and proceed to Orange Health’s page.

    • Confirm Your Details: Select the test, review prerequisites, fill in your location, and complete the booking by selecting a suitable time for sample collection.

    • Sample Collection: A trained eMedic will visit your home at the chosen time to collect the sample.

    • Lab Testing: Your sample will be analysed at our ICMR-approved and NABL-accredited lab.

    • Receive Results: Reports will be delivered via email or WhatsApp within 121 hours, and are also available on our app.

    ANA test results are interpreted as either negative or positive. A negative result reduces the likelihood of an autoimmune disease, while a positive result indicates antibodies that might suggest an autoimmune condition. High antibody levels could imply more active disease and might require additional tests.

    After scheduling an ANA test with Orange Health Labs, your sample will be collected within about 60 minutes. The collection itself is brief, and you should receive your results within 121 hours online.

    The frequency of the ANA test is determined by your healthcare provider based on your specific health requirements.

    This test measures the titre and patterns of antibodies in your blood. A lower titre suggests a lower risk of autoimmune disease, while a higher titre indicates a more active disease. Different patterns, like homogeneous and speckled, help in diagnosing diseases such as lupus and rheumatoid arthritis.

    Orange Health conducts ANA testing across various parts of Mumbai, with the added convenience of home sample collection from various localities including but not limited to Colaba, Nariman Point, Marine Drive, Malabar Hill, Churchgate, Worli, Dadar, Parel, Byculla, Bandra, Andheri, Juhu, Ghatkopar, Powai, Chembur, Vashi, Belapur, Santacruz, Khar, Versova, Lokhandwala, Goregaon, Borivali, Kandivali, Mulund, Bhandup, Kurla.

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    References

    1. Medline Plus. ANA (Antinuclear Antibody) Test: MedlinePlus Medical Test [Internet]  Available from:  https://medlineplus.gov/lab-tests/ana-antinuclear-antibody-test/
    2. Antinuclear Antibodies (ANA) Test [Internet].  Available from:  https://www.columbiadoctors.org/health-library/test/antinuclear-antibodies-ana-test/
    3. Fastest Anti-nuclear Antibody (ANA) (IFA) Test in Mumbai at Best Price + Reports in 6 Hours [Internet].  Available from:  https://www.orangehealth.in/lab-test-bangalore/anti-nuclear-antibody?utm_source=seo_search&utm_medium=google&utm_campaign=seo&utm_term=anti-nuclear-antibody