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    What is Alpha Feto Protein (AFP) Test?

    The Alpha Feto Protein (AFP) test measures the alpha fetoprotein levels in your bloodstream. Produced by the liver during cell division, this protein is highly abundant in unborn babies but becomes almost negligible after birth, remaining at trace levels in healthy non-pregnant adults and children. During pregnancy, deviations in AFP levels may suggest the presence of genetic disorders or birth defects. For individuals who are not pregnant, the test is primarily utilized as a tumour marker to detect cancers such as liver, ovarian, or testicular cancer.

    The AFP test is a useful tool for identifying potential health concerns like prenatal genetic conditions and certain cancers.

    Alpha Feto Protein (AFP) Test Parameters

    The AFP test evaluates only one parameter: the alpha feto protein level in the blood. This protein, made by the liver and yolk sac of a foetus, decreases substantially by the time a child turns one and remains at low levels in adults. Abnormal results could suggest potential health issues or necessitate further testing.

    Alpha Feto Protein (AFP) Test Preparation

    Here are some things you should know before scheduling an AFP test:

    Prerequisites : The AFP test does not require fasting beforehand.

    Best Time to Get Tested : The test is not time-sensitive and can be done at any hour of the day.

    Who Should Get an Alpha Feto Protein (AFP) Test : Consider this test if:

    • Findings from other tests or physical examinations point to possible liver, ovarian, or testicular cancer.

    • You are undergoing treatment for a cancer associated with elevated AFP levels, to track treatment outcomes.

    • You’ve completed cancer treatment and required periodic tests to check for recurrence.

    • Chronic liver diseases like hepatitis or cirrhosis increase your risk of liver cancer. A rising AFP level can signal liver cancer, and the test is sometimes paired with others to track cancer progression.

    Cautions Before Taking an Alpha Feto Protein (AFP) Test : There are no specific precautions to take prior to the test.

    Why Take the Alpha Feto Protein (AFP) Test?

    Reasons for undergoing an AFP test include:

    Cancer Diagnosis Confirmation : The test is used with other exams to diagnose or rule out cancers of the liver, ovaries, or testicles.

    Predict Cancer Behaviour : AFP testing can help anticipate how cancer will progress, assisting with treatment decisions.

    Monitor Cancer Treatment : Changes in AFP levels, rising with cancer growth and decreasing with effective treatment, allow for progress tracking.

    Check for Cancer Recurrence : AFP tests are valuable in detecting a return of cancer after treatment completion.

    Guide Treatment Decisions : In certain cases, AFP levels can help determine the best course of treatment for some cancers.

    Monitor Liver Conditions : Those with chronic liver conditions like hepatitis or cirrhosis can use AFP testing to monitor their health, as these conditions increase cancer risk.

    AFP Test During Pregnancy : Testing may also be required in these pregnancy-related situations:

    • Advanced Maternal Age : Pregnant individuals over 35 may need the test to assess foetal well-being.

    • Family History of Birth Defects : The AFP test can help identify risks of birth defects in such cases.

    • Diabetes During Pregnancy : Testing can assist in detecting complications in diabetic pregnancies.

    Alpha Feto Protein (AFP) Test Results and Interpretation

    AFP test results are typically measured in IU/mL, with a standard reference range of less than 5.5 IU/mL for healthy adults. Higher values can indicate various health concerns:

    High AFP Levels : Elevated levels may result from liver damage or benign liver diseases. They can also suggest liver, ovarian, or testicular cancer and, in rare cases, cancers like lymphoma or lung cancer. Medical history and other diagnostic tests are essential for reaching a conclusion.

    Normal AFP Levels : Levels within the normal range reduce the likelihood of cancers that elevate AFP but don’t eliminate the possibility entirely, as some cancers may not raise AFP levels.

    During Cancer Treatment : Monitoring AFP levels helps track treatment outcomes:

    • Increasing levels could indicate that the treatment isn’t effective.

    • Decreasing levels suggest the treatment is successful.

    • Stable levels may indicate no improvement or worsening of the disease.

    After Cancer Treatment : Persistently high AFP levels may indicate cancer recurrence or residual disease.

    During Pregnancy : AFP testing provides critical insights, including:

    • Identifying genetic conditions like Down syndrome or Turner syndrome.

    • Confirming or adjusting the estimated due date.

    • Detecting multiple pregnancies, such as twins or triplets.

    • Identifying neural tube defects like spina bifida or anencephaly.

    Test results can vary based on factors like age, gender, medical history, and the lab used. Elevated AFP levels during pregnancy don’t necessarily indicate a problem. It’s important to discuss your results with a doctor for an accurate interpretation.

    FAQs on Alpha Feto Protein (AFP) Test in Noida

    The AFP test in Noida costs ₹ 940. This includes home sample collection, which is available within 60 hours after booking.

    Yes, home sample collection for the AFP test is provided by Orange Health, typically within 60 minutes of booking, subject to slot availability.

    The AFP test measures blood levels of alpha feto protein to help identify certain cancers like liver, ovarian, or testicular, monitor treatment effectiveness, and assess foetal health during pregnancy for neural tube defects or genetic conditions.

    Fasting is not needed for the AFP test.

    Follow these steps to book the AFP test:

    • Search for the test on the Orange Health platform.

    • Confirm the test, review instructions, and provide your location and preferred time.

    • A trained eMedic will collect your sample at home.

    • The sample is analysed in a NABL-accredited, ICMR-certified lab.

    • Test reports are shared via app, email, or WhatsApp within 45 hours.

    In healthy adults, normal AFP levels are below 5.5 IU/mL, though these ranges may differ depending on individual health conditions.

    Reports are typically provided within 45 hours of sample collection through app, email, or WhatsApp.

    The frequency of the AFP test depends on your health condition and will be decided by your doctor.

    This test measures the level of alpha feto protein in your bloodstream.

    Orange Health offers the Alpha Feto Protein (AFP) test in Noida, with the convenience of home sample collection, so you don't have to visit a laboratory. Localities served in Noida include but are not limited to Sector 1, Sector 15, Sector 18, Sector 26, Sector 37, Sector 50, Sector 62, Sector 76, Sector 93, Sector 100, Sector 104, Sector 110, Sector 120, Sector 128, Sector 137, Sector 150, Sector 168, Sector 71, Sector 63, Sector 22, Sector 41, Sector 108, Sector 47, Sector 121, Sector 45.

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    • We do not accept cash payments
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    References

    1. AFP Tumour Marker Test. [Internet].  Available from:  https://medlineplus.gov/lab-tests/alpha-fetoprotein-afp-tumor-marker-test/
    2. Alpha Feto Protein Test. [Internet].  Available from:  https://my.clevelandclinic.org/health/diagnostics/24301-alpha-fetoprotein-test
    3. AFP Tumour Marker. [Internet].  Available from:  https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=alpha_fetoprotein_tumor_marker#:~:text=Generally%2C%20an%20AFP%20level%20between,a%20sign%20of%20liver%20tumors