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    What is Anti-HBc IgM Test?

    The Anti-HBc IgM test is a blood test used to identify IgM antibodies produced by the body in response to a recent infection with the hepatitis B virus (HBV). Hepatitis B is a viral disease that primarily affects the liver. Upon infection with the hepatitis B virus, the immune system begins to produce antibodies to fight off the infection. One specific type of antibody, known as IgM, is created in response to the hepatitis B core antigen (HBcAg). This IgM antibody typically emerges shortly after the symptoms begin and remains detectable in the blood for up to six months following infection.

    During an acute hepatitis B infection, IgM anti-HBc levels increase quickly, staying present for several weeks or months. The presence of IgM anti-HBc indicates a recent infection (within the last six months). Although the HBsAg marker is usually present during this period, it may be undetectable in some cases. Elevated liver enzyme levels are often seen during acute infections, and IgM anti-HBc can be detected even if HBsAg levels decline or disappear. A non-reactive result suggests the absence of recent infection, but it does not rule out chronic hepatitis B infection. In chronic carriers, IgM anti-HBc may appear temporarily when the disease becomes active. This test is particularly useful for differentiating acute HBV infection from other types of hepatitis.

    This test is valuable for individuals’ showing symptoms related to liver dysfunction or those who have potentially been exposed to the hepatitis B virus.

    Anti-HBc IgM Test Parameters

    The Anti-HBc IgM test assesses a single parameter: the presence of IgM antibodies targeting the hepatitis B core antigen in the blood.

    These IgM antibodies are produced when the immune system reacts to a fresh infection with the hepatitis B virus (HBV), typically indicating an infection within the past six months. A positive result points to an acute HBV infection, while in chronic hepatitis B cases, it may suggest that the virus has become active again or flared up.

    As the hepatitis B virus infects the body, the immune system responds by creating antibodies designed to neutralise the virus. There are two primary types of antibodies produced: IgM and IgG. IgM antibodies show up during acute infections and generally disappear after approximately six months, while IgG antibodies remain detectable for life, marking past or chronic infection.

    This test plays a vital role in detecting acute hepatitis B, especially in individuals showing symptoms or those who may have recently been exposed to the virus. Early detection through this test helps ensure prompt medical care and can guide doctors in determining the best course of action.

    Anti-HBc IgM Test Preparation

    When arranging for an Anti-HBc IgM test, be sure to keep the following information in mind:

    Prerequisites: No fasting or special preparation is needed before undergoing the Anti-HBc IgM test.

    Best Time to Get Tested: You can schedule the Anti-HBc IgM test at any time of the day as there are no specific timing requirements.

    Who Should Get an Anti-HBc IgM Test: This test is recommended for individuals who exhibit symptoms of hepatitis, have abnormal liver function results, have recently been exposed to hepatitis B, reside in areas with a high prevalence of hepatitis B, or are blood donors in need of screening.

    Cautions Before Taking Anti-HBc IgM Test: No specific precautions are required before taking the Anti-HBc IgM test. However, it is always a good idea to inform your doctor about any medications or conditions you have.

    Why Take the Anti-HBc IgM Test?

    The Anti-HBc IgM test is suggested for the following individuals:

    • Those recently exposed to hepatitis B : Whether through direct contact with an infected person or exposure in healthcare settings.

    • Individuals showing symptoms of hepatitis : Including yellowing of the skin (jaundice), fatigue, fever, loss of appetite, stomach discomfort, nausea, and joint pain.

    • People living in high-prevalence areas : It is crucial to distinguish between acute and chronic infections in regions with high rates of hepatitis B.

    • Those with abnormal liver function tests : When there is a possibility of hepatitis B infection based on test results.

    • Blood donors : To ensure safe transfusions through regular screening in blood banks.

    This test is an essential tool for identifying recent hepatitis B infections, enabling early diagnosis and appropriate medical intervention.

    FAQs on Anti-HBc IgM Test in Hyderabad

    The Anti-HBc IgM test in Hyderabad costs ₹1130. This price includes the convenience of home sample collection, which will take place within 60 minutes of booking confirmation. The test results will be delivered to you within 33 hours after the sample is collected.

    Yes, Orange Health Labs offers home sample collection for the Anti-HBc IgM test in Hyderabad. A skilled eMedic will arrive at your location within 60 minutes after you confirm your booking, based on available time slots.

    The Anti-HBc IgM test is primarily used to diagnose hepatitis B infections and monitor their progression. It is effective in detecting recent, acute infections (typically within the last 6 months) and can also identify changes in chronic hepatitis B carriers. A positive result indicates a recent infection, while a negative result rules out a recent infection but does not eliminate the possibility of a chronic infection. The results are best interpreted alongside your medical history and other hepatitis-related markers.

    No, fasting is not required before undergoing the Anti-HBc IgM test.

    Booking the Anti-HBc IgM test is simple by following these steps:

    • Find the test : Go to the Orange Health website and search for the Anti-HBc IgM test.

    • Confirm your booking : Enter your details, select a convenient time slot, and confirm the appointment.

    • Sample collection : After confirmation, a qualified eMedic will visit your location to collect the blood sample.

    • Processing at the laboratory : Your sample will be processed at an ICMR-certified, NABL-accredited laboratory.

    • Receive the results : Your Anti-HBc IgM test results will be sent to you via email or WhatsApp within 33 hours of the sample collection.

    Normal results for the Anti-HBc IgM test are considered negative (< 5 PEIU/ml), indicating that no recent infection has occurred. An equivocal result (5–9 PEIU/ml) suggests that the infection might be in its early stages or is resolving, while a positive result (≥ 10 PEIU/ml) indicates a recent acute infection.

    After booking the Anti-HBc IgM test, an eMedic will visit your home for sample collection within 60 minutes of confirming your booking. You will receive the results within 33 hours after the sample is collected.

    The frequency of the Anti-HBc IgM test varies depending on your health condition and your doctor’s recommendation.

    The Anti-HBc IgM test measures the presence of Anti-HBc IgM antibodies in the blood.

    Orange Health provides home sample collection for the Anti-HBc IgM test in various localities throughout Hyderabad, including areas like Banjara Hills, Jubilee Hills, Gachibowli, Madhapur, Hitech City, Kondapur, Begumpet, Somajiguda, Ameerpet, Panjagutta, Kukatpally, Miyapur, Manikonda, Secunderabad, Tarnaka, Abids, Koti, Mehdipatnam, Dilsukhnagar, Uppal, LB Nagar, Nallagandla, Nizampet, Attapur, Malkajgiri.

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    References

    1. HBc IgM (Anti-Hepatitis B core IgM) | Newfoundland & Labrador Public Health Laboratory.  Available from:  https://publichealthlab.ca/reportingname/hbc-igm-anti-hepatitis-b-core-igm/
    2. CDC. Clinical Testing and Diagnosis for Hepatitis B.  Available from:  https://www.cdc.gov/hepatitis-b/hcp/diagnosis-testing/index.html
    3. Hepatitis B Foundation. Hepatitis B Foundation: Understanding Your Hepatitis B Test Results. https://www.hepb.org/prevention-and-diagnosis/diagnosis/understanding-your-test-results/  Available from:  https://www.hepb.org/prevention-and-diagnosis/diagnosis/understanding-your-test-results/
    4. Hepatitis B Foundation. Hepatitis B Foundation: Hepatitis B Blood Tests.  Available from:  https://www.hepb.org/prevention-and-diagnosis/diagnosis/hbv-blood-tests/
    5. Clinical Significance and Remaining Issues of Anti-HBc Antibody and HBV Core-Related Antigen. Diagnostics.  Available from:  https://www.mdpi.com/2075-4418/14/7/728
    6. Hepatitis Panel: MedlinePlus Lab Test Information.  Available from:  https://medlineplus.gov/lab-tests/hepatitis-panel/