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    What is Adreno Cortico Trophic Hormone (ACTH) Test?

    The ACTH test measures levels of Adrenocorticotropic Hormone (ACTH) in the blood. Secreted by the pituitary gland located at the brain’s base, ACTH activates the adrenal glands near the kidneys to produce cortisol. Often termed the stress hormone, cortisol is vital for controlling inflammation, stabilizing blood pressure, regulating blood sugar, and supporting metabolic functions. An ACTH test is frequently performed alongside cortisol testing to assess adrenal and pituitary gland performance. Generally, when cortisol is low, ACTH production increases to stimulate cortisol release, while high cortisol suppresses ACTH secretion. This test plays a key role in diagnosing conditions like adrenal insufficiency, Cushing syndrome, and pituitary disorders, which can lead to hormonal imbalances.

    If you live in Mumbai and notice symptoms such as fatigue, weight fluctuations, or stress-related issues, consider opting for an ACTH test to investigate potential hormonal concerns.

    Adreno Cortico Trophic Hormone (ACTH) Test Parameters

    This test measures one key parameter: the level of adrenocorticotropic hormone (ACTH) in the blood. Cortisol regulation involves a collaborative effort between the hypothalamus, pituitary gland, and adrenal glands. A drop in cortisol triggers the hypothalamus to signal the pituitary gland to release ACTH, which stimulates the adrenal glands to produce cortisol. When cortisol levels are high, the system slows to restore balance. Proper coordination among these glands ensures that cortisol remains at appropriate levels for overall well-being. By analysing ACTH levels, the test helps determine if the pituitary and adrenal glands are functioning properly.

    Adreno Cortico Trophic Hormone (ACTH) Test Preparation

    To prepare for an ACTH test at home, note the following:

    • Prerequisites

    The ACTH test generally does not require fasting or any specific preparations beforehand.

    • Best Time to Get Tested

    Since ACTH levels fluctuate during the day, typically peaking in the early morning, it’s best to consult with your doctor to identify the optimal time to take the test.

    • Who Should Get an Adrenocorticotropic Hormone Test?

    Individuals who experience persistent fatigue, unexplained weight gain, muscle weakness, or other cortisol-related symptoms should consider this test.

    • Cautions Before Taking Adrenocorticotropic Hormone Test

    Although no strict preparations are necessary, certain factors can influence your ACTH levels, including:

    • Recent injuries or physical trauma.

    • High stress levels.

    • Poor sleep quality the night before the test.

    • Pregnancy or menstruation.

    • Medications such as hormones, insulin, and steroids.

    Be sure to inform your doctor about these aspects to ensure accurate test results.

    Why Take the Adreno Cortico Trophic Hormone (ACTH) Test?

    An ACTH test is essential for understanding and addressing conditions that impact cortisol production. It is particularly useful in determining whether irregular cortisol levels are caused by pituitary or adrenal gland dysfunction. This test is frequently paired with other diagnostic tools to uncover underlying hormonal issues.

    Symptoms Suggesting the Need for an ACTH Test:

    Hypopituitarism Symptoms:

    • Signs of decreased cortisol production.

    • Vision problems or headaches, often linked to tumours.

    High Cortisol Symptoms:

    • Thin limbs with fat deposits between the shoulder blades.

    • Weight gain in the face and neck areas.

    • Easy bruising, purple skin streaks, and muscle weakness.

    Low Cortisol Symptoms:

    • Reduced appetite and persistent fatigue.

    • Abdominal pain and unintended weight loss.

    • Muscle weakness.

    The ACTH test is particularly recommended for those with abnormal cortisol levels or symptoms of hormone imbalance. It aids in diagnosing conditions like Addison’s disease, Cushing’s syndrome, and hypopituitarism, leading to effective treatment.

    FAQs on Adreno Cortico Trophic Hormone (ACTH) Test in Mumbai

    In Mumbai, the ACTH test costs ₹1890. This includes hassle-free home sample collection within 60 minutes of confirmation and result delivery within 99 hours.

    Yes, Orange Health Labs facilitates home sample collection for the ACTH test in Mumbai. Once booked, a trained professional will collect your sample within 60 minutes, subject to availability.

    The ACTH test is used to check adrenal and pituitary gland function. It plays a key role in diagnosing hormonal disorders, including Addison’s disease, adrenal insufficiency, and Cushing’s disease.

    No fasting is usually needed for the ACTH test. It is recommended to consult your doctor in case any specific preparation is required.

    Follow these steps to book your ACTH test with Orange Health Labs:

    • Step 1: Search the Test : Open the Orange Health website, select the ACTH test option for Mumbai, and proceed.

    • Step 2: Confirm Booking : Fill in your details, review any preparation guidelines, and choose a convenient time slot.

    • Step 3: Home Sample Collection : A trained eMedic will collect your sample at your preferred location.

    • Step 4: Lab Processing : The sample is tested in ICMR-approved and NABL-accredited laboratories to ensure accuracy.

    • Step 5: Receive Your Results : The test results will be shared via email or WhatsApp within 99 hours. You can also view them on the Orange Health app.

    The normal reference range for ACTH levels is between 7.2 and 63.6 pg/mL. For accurate interpretation, consult your treating doctor.

    Once you confirm your test, a trained professional will collect the sample within 60 minutes. Reports are delivered online within 99 hours.

    Your doctor will determine how frequently you should take the ACTH test based on your health status and specific medical needs.

    The concentration of ACTH hormone in the bloodstream is the chief parameter included in this test.

    Orange Health provides home collection services for ACTH testing across many regions in Mumbai for added convenience. Localities like Colaba, Nariman Point, Marine Drive, Malabar Hill, Churchgate, Worli, Dadar, Parel, Byculla, Bandra, Andheri, Juhu, Ghatkopar, Powai, Chembur, Vashi, Belapur, Santacruz, Khar, Versova, Lokhandwala, Goregaon, Borivali, Kandivali, Mulund, Bhandup, and Kurla are covered.

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    References

    1. Adrenocorticotropic Hormone (ACTH) [Internet]. MedlinePlus.  Available from:  https://medlineplus.gov/lab-tests/adrenocorticotropic-hormone-acth/
    2. ACTH blood test [Internet]. UCSF Health.  Available from:  https://www.ucsfhealth.org/medical-tests/acth-blood-test
    3. ACTH (Blood) [Internet]. University of Rochester Medical Center.  Available from:  https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=acth_blood%20
    4. Adrenocorticotropic Hormone (ACTH) [Internet]. Cleveland Clinic.  Available from:  https://my.clevelandclinic.org/health/articles/23151-adrenocorticotropic-hormone-acth
    5. ACTH (Adrenocorticotropic hormone) [Internet]. Pathology Tests Explained.  Available from:  https://pathologytestsexplained.org.au/ptests.php?q=ACTH+%28Adrenocorticotropic+hormone%29