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    What Is the Angiotensin Converting Enzyme (ACE) Test?

    The Angiotensin Converting Enzyme test measures the level of angiotensin-converting enzyme (ACE) in your blood, which is produced by the cells lining your blood vessels and plays a key role in regulating blood pressure. However, when ACE levels are high, it can indicate the presence of sarcoidosis, a condition where small immune cell clusters, called granulomas, form in various organs, particularly the lungs. These granulomas can cause serious health issues. Elevated ACE levels are typically found in 50% to 80% of patients with active sarcoidosis. If a doctor suspects sarcoidosis due to symptoms such as a chronic cough, difficulty breathing, or joint pain, they may recommend this test.

    In addition to sarcoidosis, elevated ACE levels can be linked to other health issues, including infections like tuberculosis or exposure to certain chemicals. If your ACE levels are high, further tests may be necessary to identify the underlying cause.

    While ACE is a naturally occurring protein in your body, medications called ACE inhibitors, which are used to lower blood pressure, may interfere with test results.

    If you live in Mumbai and have symptoms like a persistent cough, breathlessness, or joint pain, you might want to consider booking an ACE test to help diagnose conditions like sarcoidosis.

    Angiotensin Converting Enzyme (ACE) Test Parameters

    The Angiotensin Converting Enzyme test measures the concentration of angiotensin-converting enzyme in the blood.

    This enzyme is crucial for controlling blood pressure by converting angiotensin I into angiotensin II, which causes blood vessels to constrict and increases blood pressure. The majority of ACE is found in the lungs, although it is also present in other areas of the body. People under the age of 20 tend to have higher levels of ACE, but as you age, your ACE levels decrease and stabilise.

    ACE is also produced by certain cells in response to infection or inflammation. These immune cells form small clusters called granulomas, which are commonly seen in conditions like sarcoidosis, where they are mainly found in the lungs and other organs.

    Angiotensin Converting Enzyme (ACE) Test Preparation

    When booking an Angiotensin Converting Enzyme test, consider the following:

    Prerequisites There is no need to fast before taking the Angiotensin Converting Enzyme test.

    Best Time to Get Tested The test can be taken at any time during the day that suits you.

    Who Should Get an Angiotensin Converting Enzyme Test? This test is commonly recommended for individuals showing symptoms such as unexplained breathlessness, chronic cough, joint pain, or sudden weight fluctuations, which may be indicative of conditions like sarcoidosis or other related issues.

    Cautions Before Taking Angiotensin Converting Enzyme Test

    No specific precautions need to be observed prior to the test.

    Why Take the Angiotensin Converting Enzyme (ACE) Test?

    The ACE test is primarily used to diagnose sarcoidosis or other diseases that may cause granulomas, which are small clusters of immune cells that can form in various organs, leading to diverse symptoms. If you experience any of the following, the ACE test could provide valuable insights:

    • Persistent cough, difficulty breathing, or wheezing

    • Unexplained fatigue

    • Unexplained weight loss or a decrease in appetite

    • Chest pain

    • Joint stiffness or pain

    • Vision problems

    • Dry mouth

    • Headaches

    • Skin changes, such as rashes, sores, or hardened spots

    • Fever

    The test is especially important for people between the ages of 20 and 40, as this is the age group most commonly affected by sarcoidosis. The ACE test can also help distinguish between sarcoidosis and other conditions that cause granulomas, such as infections.

    For individuals diagnosed with sarcoidosis who initially had high ACE levels, repeating the test can be useful in monitoring disease progression and evaluating treatment effectiveness.

    FAQs on the Angiotensin Converting Enzyme (ACE) Test in Mumbai

    The cost for the Angiotensin Converting Enzyme test in Mumbai is ₹1232. This price covers home sample collection, which will occur within 60 minutes of your booking confirmation. The results will be delivered within 72 hours after the sample is collected.

    Yes, Orange Health Labs provides at-home sample collection for the Angiotensin Converting Enzyme test at home. A certified eMedic will arrive at your chosen location within 60 minutes of booking confirmation, depending on slot availability.

    The Angiotensin Converting Enzyme test determines the levels of ACE in the blood, which can help identify conditions like sarcoidosis, lung diseases, and liver ailments. Elevated ACE levels are typically linked to various inflammatory medical conditions.

    An ACE test generally doesn’t require fasting, but it’s always wise to follow any specific advice your doctor gives.

    To book an Angiotensin Converting Enzyme test, follow these simple steps: • Search for the test: Visit the Orange Health website and choose the Angiotensin Converting Enzyme test. • Confirm your booking: Enter your details, choose a suitable time, and confirm your appointment. • Sample collection: After confirmation, a trained eMedic will visit your location to collect the sample. • Laboratory processing: Your sample will be processed in an ICMR-certified and NABL-accredited laboratory. • Results : You will receive the results via email or WhatsApp within 72 hours after collection and can view them on the Orange Health app.

    Typically, normal ACE levels in the blood fall between 12 and 68 units per litre (u/L).

    After booking the Angiotensin Converting Enzyme test, an eMedic will collect your sample within 60 minutes. You can expect to get your results within 72 hours after the sample has been collected.

    The frequency of the Angiotensin Converting Enzyme test is influenced by your health condition and personal circumstances. It’s advisable to consult your doctor for the best course of action.

    The Angiotensin Converting Enzyme test measures the concentration of angiotensin-converting enzyme in your blood.

    Orange Health offers home sample collection for the Angiotensin Converting Enzyme test in multiple locations throughout Mumbai, including areas such as Colaba, Dadar, Parel, Byculla, Bandra, Andheri, Juhu, Ghatkopar, Powai, Chembur, Vashi, Belapur, Santacruz, Khar, Versova, Lokhandwala, Goregaon, Borivali, Kandivali, Mulund, Bhandup, Nariman Point, Marine Drive, Malabar Hill, Churchgate, Worli, and Kurla.

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    References

    1. Angiotensin converting enzyme (ACE) | Pathology Tests Explained [Internet].  Available from:  https://www.pathologytestsexplained.org.au/ptests-pro.php?q=ACE+%28Angiotensin+converting+enzyme%29
    2. Angiotensin Converting Enzyme (Blood) [Internet].  Available from:  https://www.urmc.rochester.edu/encyclopedia/content?ContentTypeID=167&ContentID=angiotensin_converting_enzyme_blood
    3. Kahkouee S, Samadi K, Alai A, Abedini A, Rezaiian L. Serum ACE Level in Sarcoidosis Patients with Typical and Atypical HRCT Manifestation. Polish Journal of Radiology [Internet].  Available from:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036380/