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    Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA2924262510% off
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    What Is Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test?

    The Anti Neutrophil Cytoplasmic Antibody (ANCA) test is a blood test that helps detect specific proteins made by the immune system. Normally, these proteins fight infections, but in some cases, they attack healthy white blood cells, such as neutrophils and monocytes, by mistake.

    This test plays a key role in diagnosing ANCA-associated vasculitis, a condition that leads to inflammation of the blood vessels. When blood vessels become inflamed, they may narrow, weaken, or get blocked, which can damage vital organs like the kidneys, lungs, eyes, and skin. Early signs of vasculitis include tiredness, weight loss, muscle aches, and fever. If untreated, it can cause lasting harm to organs.

    The two main proteins linked to this condition are:

    • Myeloperoxidase (MPO): Frequently found in microscopic polyangiitis (MPA), a condition that affects small blood vessels.

    • Proteinase 3 (PR3): Often seen in granulomatosis with polyangiitis (GPA), a condition that affects the lungs and sinuses.

    To confirm the diagnosis and monitor progress, additional tests such as PR3 ANCA, inflammation markers, kidney function tests, and full blood counts may be required.

    Individuals staying in Mumbai have the option to take the Anti Neutrophil Cytoplasmic Antibody (ANCA) test at home, making sample collection and result delivery easy and hassle-free.

    Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test Parameters The ANCA test is used to detect the presence of PR3 and MPO autoantibodies in the blood.

    The two main proteins targeted by these autoantibodies are:

    cANCA (cytoplasmic ANCA)

    Attacks PR3, a protein that helps control blood cell production and regulates cell death.

    pANCA (perinuclear ANCA)

    Targets MPO, a protein that is vital for fighting infections.

    The presence of ANCAs activates neutrophils, prompting them to release chemicals that cause swelling, inflammation, and damage to blood vessels. This can harm organs such as the kidneys, skin, and lungs. As neutrophils move through blood vessel walls, they release even more chemicals, increasing inflammation and worsening tissue damage.

    People with ANCA, MPO, and PR3 autoantibodies may continue producing them even when they are undetectable in tests. A positive ANCA test is typically linked to vasculitis but may also be seen in inflammatory bowel disease, rheumatoid arthritis, and infections like respiratory infections or endocarditis, and with certain medications.

    Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test Preparation

    If you are planning to take the Anti Neutrophil Cytoplasmic Antibody (ANCA) test at home, here’s what you should know:

    • Prerequisites : No special preparation is necessary for the ANCA test, and you do not need to fast before taking the test.

    • Best Time to Get Tested : The ANCA test can be scheduled at any time that is convenient for you.

    • Who Should Get an Anti Neutrophil Cytoplasmic Antibody (ANCA) Test? If you have ongoing tiredness, weight loss, joint pain, fever, or symptoms that affect your skin, kidneys, lungs, or nervous system, an ANCA test may help detect autoimmune vasculitis.

    • Cautions Before Taking an Anti Neutrophil Cytoplasmic Antibody (ANCA) Test : There are no specific precautions needed before the ANCA test.

    Why Take the Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test?

    You may need the ANCA test if you are experiencing:

    • Unexplained symptoms such as fever, night sweats, fatigue, muscle aches, joint pain, or weight loss.

    • Issues affecting different organs:

      • Eyes, ears, and nose: Blurry vision, hearing problems, or sinus infections.

      • Skin: Itching, rashes, or bruising.

      • Lungs: Trouble breathing or coughing up blood.

      • Kidneys: Blood or protein found in urine.

      • Nervous system: Tingling, numbness, or shooting pains.

      • Digestive system: Stomach pain, diarrhoea, or vomiting blood.

    • Suspected autoimmune diseases such as GPA or MPA.

    • Symptoms of inflammatory bowel disease, including diarrhoea, bloody stools, or ongoing fever.

    • Regular testing if you have already been diagnosed with autoimmune vasculitis.

    By detecting vasculitis early, the ANCA test can help manage symptoms effectively and prevent long-term damage to vital organs.

    FAQs on Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test in Mumbai

    You can get the Anti Neutrophil Cytoplasmic Antibody (ANCA) test in Bangalore for ₹2625. The test includes home sample collection, which is completed within 60 minutes of booking. Orange Health Labs ensures that you receive your test results within 69 hours after sample collection.

    Yes, Orange Health Labs makes it simple to get the Anti Neutrophil Cytoplasmic Antibody (ANCA) test at home. A certified eMedic professional will visit your location within 60 minutes of booking to collect your blood sample.

    By detecting specific autoantibodies in the blood, the ANCA test helps diagnose autoimmune diseases like vasculitis, which can lead to inflammation and damage in blood vessels and organs.

    No, the ANCA test does not require fasting before the test.

    Booking the ANCA test with Orange Health Labs is a hassle-free process:

    • Search for the Test: Search for the "Anti Neutrophil Cytoplasmic Antibody (ANCA) Test" online and choose Orange Health Labs.

    • Confirm Your Booking: Enter your information, select your location, and choose a convenient time for sample collection.

    • Sample Collection: A certified eMedic professional will visit your location to collect your blood sample.

    • Analysis & Results: The sample will be tested at our NABL-accredited, ICMR-approved laboratory, and your results will be sent via email or WhatsApp within 69 hours.

    A negative ANCA test result, showing no p-ANCA or c-ANCA autoantibodies, is considered normal and helps rule out autoimmune vasculitis. A positive result showing the presence of the antibodies needs further evaluation for autoimmune disorders.

    The ANCA test results are typically provided within 69 hours following sample collection.

    How often you require the ANCA test will depend on your health status and should be advised by your doctor.

    Antibodies such as PR3 and MPO are measured in the ANCA test.

    In Mumbai, the ANCA test is available in numerous locations, including but not limited to Colaba, Nariman Point, Marine Drive, Malabar Hill, Churchgate, Worli, Dadar, Parel, Byculla, Bandra, Andheri, Juhu, Ghatkopar, Powai, Chembur, Vashi, Belapur, Santacruz, Khar, Versova, Lokhandwala, Goregaon, Borivali, Kandivali, Mulund, Bhandup, Kurla.

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    References

    1. Antineutrophil Cytoplasmic Antibodies (ANCA) Test: MedlinePlus Medical Test.  Available from:  https://medlineplus.gov/lab-tests/antineutrophil-cytoplasmic-antibodies-anca-test/
    2. Antineutrophil Cytoplasmic Antibodies (ANCA) Test: What It Is. 3. Antineutrophil cytoplasmic antibodies (ANCA) | Pathology Tests Explained. 4. Khalid N, Aeddula NR. Antinuclear Cytoplasmic Antibody [Internet]. PubMed. Treasure Island (FL). 5. The value of anti-neutrophil cytoplasmic antibodies (ANCA) testing for the diagnosis of ANCA-associated vasculitis, a systematic review and meta-analysis.  Available from:  https://my.clevelandclinic.org/health/diagnostics/22512-anca-test