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    What Is a CA 72.4, Gastric Cancer Marker Test?

    The CA 72.4 Gastric Marker test is a blood test designed to measure the levels of Cancer Antigen 72.4 (CA 72.4), a marker primarily linked to gastric cancer (GC). Gastric cancer is one of the most aggressive and fatal forms of cancer worldwide, often diagnosed in advanced stages due to the absence of early warning signs and effective screening methods.

    While upper gastrointestinal endoscopy with biopsy is considered the gold standard for diagnosing gastric cancer, it is an invasive, expensive procedure that is not always suitable for frequent monitoring. This is why non-invasive tumour markers like CA 72.4 are increasingly used to detect and monitor gastric cancer progression. Additionally, research has shown that CA 72.4 offers superior diagnostic accuracy compared to other tumour markers, such as CEA (carcinoembryonic antigen) and CA 19-9, for detecting gastric cancer. The test is also valuable in assessing whether a patient is a candidate for tumour resection surgery.

    For those living in Mumbai, arranging a CA 72.4 test at home is an easy and convenient option for early diagnosis and continuous monitoring of gastric cancer.

    CA 72.4, Gastric Cancer Marker Test Parameters

    The CA 72.4 test measures the amount of the gastric cancer marker CA 72.4 in the blood.

    CA 72.4, or Tumour-Associated Antigen 72 (TAG-72), is a glycoprotein that is found in high concentrations on the surface of several types of adenocarcinomas, including gastric, colorectal, ovarian, and breast cancers. While its levels are typically low in healthy individuals, they rise significantly in the presence of malignant tumours. Elevated levels of CA 72.4 are most often associated with gastric cancer, particularly in the later stages.

    CA 72.4, Gastric Cancer Marker Test Preparation

    To prepare for the CA 72.4 test at home, please review the following testing guidelines:

    • Prerequisites No fasting is required before the CA 72.4 gastric cancer marker test.

    • Best Time to Get Tested The CA 72.4 test can be scheduled at any point during the day for individuals seeking diagnosis or monitoring of gastric cancer.

    • Who Should Get a CA 72.4 Test? The CA 72.4 test is recommended for people being evaluated for gastric cancer or other adenocarcinomas, those requiring postoperative monitoring, and individuals undergoing chemotherapy to evaluate their response to treatment. It may also be suggested for those at higher risk of gastric cancer, such as those with a family history, poor eating habits, or Helicobacter pylori infection.

    • Cautions Before Taking a CA 72.4 Test No specific precautions are needed prior to the test.

    Why Take the CA 72.4, Gastric Cancer Marker Test?

    The CA 72.4 test is significant for individuals at risk of or diagnosed with gastric cancer. It is important for the following reasons:

    • Early Detection of Gastric Cancer : Although it is not a definitive screening tool, CA 72.4 can support the early detection of gastric cancer, particularly in those at high risk.

    • Assessing Disease Progression : It helps assess tumour burden and predict metastasis (the spread of cancer to other body parts) prior to surgery.

    • Postoperative Monitoring : The test is valuable in monitoring for tumour recurrence after surgery.

    • Evaluating Treatment Response : The test also helps monitor the response to chemotherapy and assists in making therapeutic decisions.

    Regular monitoring of CA 72.4 levels, along with imaging, and clinical evaluation helps monitor the progression of disease, treatment response, and potential recurrence of gastric cancer and other adenocarcinomas.

    FAQs on the CA 72.4, Gastric Cancer Marker Test in Mumbai

    The CA 72.4 test in Mumbai is available for ₹1930. This includes home sample collection within 60 minutes. Test results are generally available within 245 hours after the sample has been collected.

    Yes, Orange Health Labs does offer home sample collection for the CA 72.4 test. A trained eMedic will arrive at your location within 60 minutes of booking to collect your sample.

    The CA 72.4 test is chiefly used as a tumour marker for the detection and monitoring of gastric cancer. It aids in evaluating cancer progression, recurrence, and treatment response in patients undergoing therapy. Furthermore, elevated levels of CA 72.4 may signal other adenocarcinomas, such as colorectal, ovarian, lung, and breast cancers.

    You do not need to fast before taking the CA 72.4 test.

    Booking your CA 72.4 test with Orange Health Labs is fast and easy:

    • Find the Test : Search for the “CA 72.4 Gastric Cancer Marker test” on the Orange Health Labs platform.

    • Confirm Your Appointment : Enter your details, select your preferred testing location, and pick a time that’s convenient for you.

    • Sample Collection : A trained eMedic will come to your home to collect the sample.

    • Laboratory Analysis : The sample will be processed at an NABL-accredited, ICMR-approved laboratory.

    • Receive Results : Your test results will be delivered via email or WhatsApp within 245 hours.

    Normal CA 72.4 levels are typically below 6.9 U/mL, with higher levels potentially indicating gastric cancer or other malignancies. The results should always be reviewed by a doctor, who will take the individual’s medical history into account.

    The results for the CA 72.4 Gastric Marker test are generally available within 245 hours of the sample being collected.

    How often the test is conducted depends on your doctor’s guidance. It may be repeated periodically to track the progression, recurrence, or treatment response of cancer in diagnosed patients.

    The CA 72.4 test measures the Cancer Antigen 72.4 (CA 72.4) level in the blood. It plays a role in assessing gastric cancer presence, recurrence, and metastasis and may also suggest other cancers, including colorectal, ovarian, and lung malignancies.

    Orange Health Labs provides home sample collection for the CA 72.4 test across multiple localities in Mumbai, including but not limited to Colaba, Dadar, Parel, Byculla, Bandra, Andheri, Juhu, Ghatkopar, Powai, Chembur, Vashi, Belapur, Santacruz, Khar, Versova, Lokhandwala, Goregaon, Borivali, Kandivali, Mulund, Bhandup, Nariman Point, Marine Drive, Malabar Hill, Churchgate, Worli, and Kurla.

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    References

    1. ‌1. Xu Y, Zhang P, Zhang K, Huang C. The application of CA72-4 in the diagnosis, prognosis, and treatment of gastric cancer. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer.  Available from:  https://www.sciencedirect.com/science/article/pii/S0304419X21001323
    2. P. Piantino, Taccone W, Fusaro A, E. Daziano, R. Polloni, Mosso R. Significance of CA 72.4 Serum Levels in Gastrointestinal Diseases. The International Journal of Biological Markers. 3. Călin Căinap, Nagy V, Gherman A, Sanziana Cetean, Laszlo I, Constantin AM, et al. Classic Tumor Markers in Gastric Cancer. Current Standards and Limitations. Medicine and Pharmacy Reports.  Available from:  https://pubmed.ncbi.nlm.nih.gov/2283481/