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    What is Calcium Creatinine Ratio, Urine Test?

    The Calcium Creatinine Ratio test is a diagnostic urine test that evaluates the amounts of calcium and creatinine eliminated through urine. Creatinine is a substance formed during regular muscle activity. This test calculates the ratio of calcium to creatinine, providing an accurate insight into calcium metabolism and helping identify abnormalities such as hypercalciuria (high calcium levels in urine) or hypocalciuria (low calcium levels in urine). It is a vital method to check kidney health and maintain calcium balance in the body.

    This test is crucial for diagnosing conditions associated with calcium metabolism issues. Excessive calcium excretion might point to conditions like hyperparathyroidism (overactive parathyroid glands), kidney stones, or genetic disorders like familial hypocalciuric hypercalcemia (FHH). Conversely, low calcium levels in urine may indicate hypoparathyroidism or vitamin D deficiency. Studies suggest that this test can also assist in detecting preeclampsia (a pregnancy-related condition with high blood pressure).

    For children, the test provides a non-invasive way to diagnose hypercalciuria and other metabolic disorders. For adults, it is particularly helpful for evaluating recurring kidney stones or a family history of calcium imbalance.

    If you're in Mumbai and considering a Calcium Creatinine Ratio test, consult with your physician to determine if this test is appropriate for you.

    Calcium Creatinine Ratio, Urine Test Parameters

    The Calcium Creatinine Ratio test evaluates three primary parameters: calcium concentration, creatinine concentration, and Calcium Creatinine Ratio in a urine sample.

    Calcium Levels in Urine

    This parameter measures the total calcium eliminated through urine. Abnormally high levels may indicate hypercalciuria, while low levels suggest hypocalciuria. These abnormalities can be linked to underlying metabolic disorders or kidney issues.

    Creatinine Levels in Urine

    Creatinine, a natural byproduct of muscle activity, is excreted through urine. Its levels serve as a benchmark to interpret calcium excretion. If creatinine levels are elevated without a corresponding rise in calcium, it could signify reduced kidney efficiency or metabolic dysfunctions.

    Calcium-Creatinine Ratio

    This ratio is calculated by dividing the calcium concentration (mg/dL) in the urine by the creatinine concentration (mg/dL). It normalises calcium excretion against kidney filtration capability. A ratio higher than normal suggests hyperparathyroidism, kidney stones, or excessive calcium intake, while lower ratios point to conditions like reduced calcium absorption or parathyroid gland underactivity.

    Calcium Creatinine Ratio, Urine Test Preparation

    You can get the Calcium Creatinine Ratio test at home by following these guidelines:

    • Prerequisites

    Fasting is not typically required unless specified by your doctor.

    • Best Time to Get Tested

    This test usually uses a random urine sample, making it convenient to schedule at any time during the day.

    • Who Should Get a Calcium Creatinine Ratio Test?

    The Calcium Creatinine Ratio test is ideal for individuals who experience recurrent kidney stones, exhibit symptoms of metabolic disorders, or have potential calcium metabolism abnormalities. It is also beneficial for those with a family history of hypercalciuria, hyperparathyroidism, or similar conditions.

    • Cautions Before Taking a Calcium Creatinine Ratio Test

    Notify your doctor about any medications or supplements you are currently taking, as these can influence calcium or creatinine levels in the urine.

    Why Take the Calcium Creatinine Ratio, Urine Test?

    The Calcium Creatinine Ratio test is essential for detecting and managing various conditions linked to calcium metabolism. Below are the primary reasons for undergoing this test:

    • To Identify Kidney Stones: This test detects elevated calcium excretion, a common factor in the formation of calcium-based kidney stones. It is recommended for individuals with symptoms like intense abdominal pain, blood-stained urine, or frequent urination.

    • To Assess Kidney Function: The test measures your kidneys’ efficiency in filtering calcium, helping to diagnose disorders related to kidney function. Abnormal values may point to kidney damage or disrupted calcium regulation.

    • To Investigate Parathyroid Conditions: Parathyroid hormone (PTH) imbalances can result in calcium dysregulation. This test aids in evaluating disorders such as hyperparathyroidism or hypoparathyroidism and determining their impact.

    • To Examine Bone Health Problems: It helps diagnose bone conditions such as osteoporosis by identifying abnormalities in calcium metabolism, especially when irregularities are observed in calcium blood tests.

    • To Diagnose Genetic Conditions : Genetic disorders like familial hypocalciuric hypercalcemia (FHH) can alter calcium excretion. This test helps differentiate between genetic and other metabolic causes.

    FAQs on Calcium Creatinine Ratio, Urine Test in Mumbai

    The price for this test in Mumbai is ₹500. It also includes a home sample collection service, which is available within 60 minutes of confirming your booking.

    Yes, Orange Health Labs ensures you can conveniently have your sample collected from the comfort of your home, making the testing process smooth and easy.

    The Calcium Creatinine Ratio test evaluates the calcium and creatinine levels in your urine, making it crucial for diagnosing disorders like calcium-based kidney stones, metabolic abnormalities, hyperparathyroidism, osteoporosis, and rare genetic conditions affecting calcium balance.

    Fasting is generally unnecessary for the Calcium Creatinine Ratio test. However, discussing additional test requirements with your doctor is advisable to prevent potential interference.

    Here’s how you can schedule the Calcium Creatinine Ratio test at home:

    • Search for the test: Search like "Calcium Creatinine Ratio test in Mumbai" or "Calcium Creatinine Ratio test at home" and pick Orange Health Labs.

    • Finalise your booking: Choose the test, follow the instructions, share your address, and set a time for the sample collection.

    • Doorstep sample collection: A certified eMedic will collect your sample at the designated time, ensuring a smooth process.

    • Laboratory testing: Your sample will undergo processing in an ICMR-approved, NABL-accredited laboratory for analysis.

    • Access your results: Receive your test results through email or WhatsApp within 3 hours of sample collection. You can also access the reports on the Orange Health app.

    A Calcium Creatinine Ratio test is considered normal when the ratio is less than 0.2. Higher values may indicate hypercalciuria, which is commonly linked to calcium-related kidney stones or other metabolic issues. Lower values could mean hypocalciuria, often due to parathyroid dysfunction or calcium absorption problems.

    After confirming your booking, a certified eMedic will collect your sample within 60 minutes. The final reports will be sent via WhatsApp or email within 3 hours.

    The frequency is determined by your doctor and depends on your condition, such as recurrent kidney stones, abnormal calcium levels, or a diagnosis requiring regular monitoring.

    The test measures calcium and creatinine levels in urine and the calcium-to-creatinine ratio.

    Orange Health Labs offers this test in several Mumbai localities, including Colaba, Nariman Point, Marine Drive, Malabar Hill, Churchgate, Worli, Dadar, Parel, Byculla, Bandra, Andheri, Juhu, Ghatkopar, Powai, Chembur, Vashi, Belapur, Santacruz, Khar, Versova, Lokhandwala, Goregaon, Borivali, Kandivali, Mulund, Bhandup, Kurla.

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    References

    1. Foley KF, Boccuzzi L. Urine Calcium: Laboratory Measurement and Clinical Utility. Laboratory Medicine [Internet].  Available from:  https://academic.oup.com/labmed/article-abstract/41/11/683/2504912?redirectedFrom=fulltext
    2. Choi IS, Jung ES, Choi YE, Cho YK, Yang EM, Kim CJ. Random Urinary Calcium/Creatinine Ratio for Screening Hypercalciuria in Children with Hematuria. Annals of Laboratory Medicine [Internet].  Available from:  https://pmc.ncbi.nlm.nih.gov/articles/PMC3819437/
    3. Creatinine [Internet]. National Kidney Foundation.  Available from:  https://www.kidney.org/kidney-topics/creatinine
    4. Rodriguez MHellen, Masaki DI, Mestman J, Kumar D, Rude R. Calcium/creatinine ratio and microalbuminuria in the prediction of preeclampsia.  Available from:  https://pubmed.ncbi.nlm.nih.gov/3061296/
    5. Wills MR. The urinary calcium/creatinine ratio is a measure of urinary calcium excretion. Journal of Clinical Pathology.  Available from:  https://jcp.bmj.com/content/22/3/287
    6. Calcium in Urine Test [Internet].  Available from:  https://medlineplus.gov/lab-tests/calcium-in-urine-test/