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    What Is the Cardiolipin antibody IgA Test?

    The Cardiolipin Antibody IgA test detects the presence of anti-cardiolipin antibodies in the blood. These antibodies mistakenly attack cardiolipins, which are the phospholipids that are crucial for proper blood clotting. This immune error can interfere with clotting, reduce platelet levels, and result in bleeding problems. Elevated cardiolipin antibodies are commonly associated with autoimmune diseases like systemic lupus erythematosus (SLE), recurrent miscarriages, and clotting disorders. This test is particularly useful for diagnosing primary antiphospholipid syndrome (APS) and understanding the causes of repeated thrombosis or pregnancy loss. Additionally, it is valuable in monitoring autoimmune disorders and infections involving these antibodies.

    If you are residing in Bangalore, you can even schedule the Cardiolipin Antibody IgA test at home for your convenience.

    Cardiolipin antibody IgA Test Parameters

    The test measures the levels of IgA antibodies produced in the blood against cardiolipins, which play a critical role in blood clotting.

    These antibodies are often elevated in individuals with autoimmune diseases, leading to abnormal clotting tendencies. These antibodies are mistakenly produced by the immune system and can contribute to conditions like APS, where blood clots form abnormally. This test is vital for detecting and managing clotting disorders associated with autoimmune diseases.

    Cardiolipin antibody IgA Test Preparation

    Here’s how to prepare for the Cardiolipin Antibody IgA test at home:

    • Prerequisites : There are no prerequisites for this test and it does not require fasting.

    • Best Time to Get Tested : The Cardiolipin Antibody IgA test can be done at any time of the day that works for you.

    • Who Should Get a Cardiolipin Antibody IgA Test? : Those with unexplained or recurrent blood clots, whether venous or arterial, as well as individuals with autoimmune conditions like SLE or suspected APS, should get this test.

    • Cautions Before Taking a Cardiolipin Antibody IgA Test : Notify your doctor about any medications or supplements you are currently taking before the test.

    Why Take the Cardiolipin antibody IgA Test?

    The Cardiolipin Antibody IgA test assists in diagnosing conditions related to abnormal clotting or bleeding, particularly for those with a history of recurrent miscarriages or unexplained thrombotic events. The test serves to:

    • Identify unexplained bleeding or clotting occurrences.

    • Diagnose autoimmune conditions such as lupus or antiphospholipid syndrome, which often involve cardiolipin antibodies.

    • Investigate the role of anti-phospholipid antibodies in thrombotic events, particularly in patients without clear thrombotic symptoms.

    • Detect elevated levels of IgA antibodies, which could suggest underlying autoimmune diseases or unexplained clotting.

    • Evaluate the possibility of false-positive VDRL (syphilis) test results, which are commonly seen in lupus patients with anti-cardiolipin antibodies.

    • Investigate potential causes in individuals with a history of recurrent miscarriages.

    FAQs on the Cardiolipin antibody IgA Test in Mumbai

    The Cardiolipin Antibody IgA test in Mumbai costs ₹1000, including quick home sample collection and timely delivery of test results.

    Yes, home sample collection is available for Cardiolipin Antibody IgA test at home with Orange Health Labs. A trained eMedic will arrive at your chosen location to collect your sample, within 60 minutes of booking.

    The Cardiolipin IgA Antibody test detects IgA antibodies against cardiolipins in the bloodstream, which can contribute to abnormal clotting. It is frequently used to diagnose conditions like antiphospholipid syndrome, autoimmune disorders such as systemic lupus erythematosus, and recurring miscarriages.

    No, fasting is not required for the Cardiolipin Antibody test.

    You can follow these steps to book the Cardiolipin Antibody IgA test with Orange Health Labs:

    • Locate the Test: Look for the " Cardiolipin Antibody IgA test" and select Orange Health Labs.

    • Confirm the Appointment: Enter your details, choose your location, and select a convenient time for sample collection.

    • Sample Collection: A trained eMedic will collect the sample from your chosen location.

    • Laboratory Testing: The sample will be analysed at an NABL-accredited, ICMR-approved laboratory.

    • Results: You will receive your results via email or WhatsApp within 132 hours.

    The normal levels for the Cardiolipin Antibody test are as follows:

    • Negative: <10 units

    • Positive: ≥10 units

    A positive result can signal the presence of cardiolipin antibodies, which may be linked to conditions like autoimmune diseases or antiphospholipid syndrome.

    With Orange Health Labs, you promptly receive the results of the Cardiolipin Antibody IgA test online, typically within 89 hours of sample collection.

    Your doctor will decide how frequently to perform the Cardiolipin Antibody IgA test. It is sometimes conducted periodically to keep a check on autoimmune diseases, blood clotting issues, or multiple miscarriages.

    By measuring the IgA antibodies present against cardiolipins in the blood, this test helps identify potential autoimmune conditions, including antiphospholipid syndrome.

    Orange Health Labs offers home sample collection for the Cardiolipin Antibody IgA test across several localities in Mumbai, including Colaba, Nariman Point, Marine Drive, Malabar Hill, Churchgate, Worli, Dadar, Parel, Byculla, Bandra, Andheri, Juhu, Ghatkopar, Powai, Chembur, Vashi, Belapur, Santacruz, Khar, Versova, Lokhandwala, Goregaon, Borivali, Kandivali, Mulund, Bhandup, Kurla.

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    References

    1. Cardiolipin Antibody - Health Encyclopedia - University of Rochester Medical Center.  Available from:  https://www.urmc.rochester.edu/encyclopedia/content?contenttypeid=167&contentid=cardiolipin_antibody
    2. Anti-cardiolipin antibody (ACL) - South Tees Hospitals NHS Foundation Trust.  Available from:  https://www.southtees.nhs.uk/services/pathology/tests/anti-cardiolipin-antibody-acl/
    3. Andreoli L, Fredi M, Nalli C, Piantoni S, Rossella Reggia, Dall’Ara F, et al. Clinical Significance of IgA Anti-Cardiolipin and IgA Anti-β2Glycoprotein I Antibodies. Current Rheumatology Reports.  Available from:  https://pubmed.ncbi.nlm.nih.gov/23754504/