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    CD 20, Flow Cytometry5143252051% off
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    What is CD 20, Flow Cytometry Test?

    The CD20 test measures the amount of CD20 protein present in B-cells, a type of white blood cell. This protein is crucial for the immune system as it helps in B-cell growth and maturity. The test is primarily used to diagnose and track B-cell-associated cancers, such as lymphoma.

    Lymphomas are cancers originating in the lymphatic system, a core part of the body’s immune function. When B-cells become cancerous, they are classified as B-cell lymphomas. The levels of CD20 on B-cells vary depending on the lymphoma type, and lower CD20 levels may impact the effectiveness of targeted therapies like rituximab.

    The CD20 Marker Flow Cytometry test is conducted using flow cytometry, an advanced method that examines how CD20 is expressed on B-cells and identifies any abnormalities. This detailed information assists in tailoring treatment plans for lymphoma patients. For instance, if CD20 expression is reduced or absent, alternative therapies can be explored to improve patient outcomes.

    In Mumbai, you can conveniently take the CD20 test at home, making it easier to get timely and accurate test results.

    CD 20, Flow Cytometry Test Parameters

    The CD20 test evaluates a single parameter: the CD20 cell count, represented as both an absolute count and a percentage of lymphocytes in the bloodstream.

    CD20 is a protein located on the surface of B-cells, which play a fundamental role in the immune system’s defense against infections. This protein first appears during the early stages of B-cell development and is essential for their activation, growth, and maturation processes. However, once B-cells transition into plasma cells (their final developmental stage), they lose the CD20 protein. This loss makes CD20 an important marker for monitoring B-cell development.

    While CD20 is primarily found on B-cells, it is also observed in a smaller population of T-cells, though its primary role is with B-cells. Variations in CD20 expression across different types of B-cell cancers can provide valuable information about the disease and help plan for treatments accordingly. Besides serving as a marker, CD20 has a functional role in regulating B-cell activity by enabling calcium to enter the cells. This calcium entry is critical for B-cells to carry out their immune system function effectively and efficiently.

    CD 20, Flow Cytometry Test Preparation

    Here are the important details you should be aware of before taking the CD20 test at home:

    • Prerequisites

    No fasting or special preparation is required for the CD20 test.

    • Best Time to Get Tested

    You can take the CD20 test at any time that works best for you since there are no specific time-related requirements.

    • Who Should Get a CD20 Test?

    The CD20 test is typically advised for individuals showing symptoms of B-cell-related cancers, like leukaemia or lymphoma, as it plays a key role in diagnosing and monitoring these illnesses.

    • Cautions Before Taking a CD20 Test

    There aren’t any particular precautions needed for the CD20 test.

    Why Take the CD 20, Flow Cytometry Test?

    The CD20 blood test is an important diagnostic and monitoring tool, especially for B-cell lymphomas. Here’s how it helps:

    • Identifies Lymphoma Subtypes : It helps doctors confirm and identify the specific type of lymphoma you may have.

    • Improves Treatment Planning : By checking CD20 levels, your doctor can determine if therapies like rituximab are likely to work for you.

    • Tracks Disease Progression : This test monitors how your condition is changing, whether improving, stable, or worsening.

    • Highlights High-Risk Situations : It identifies patients who may have a higher risk due to low or abnormal CD20 expression levels.

    • Ensures Treatment Effectiveness : If treatments aren’t giving the desired effect, the test results will suggest when to make changes.

    • Tailors Therapy : Knowing your CD20 levels helps to personalise your treatment plan, providing the best possible approach for your health.

    If you’re dealing with lymphoma or related conditions, this test gives essential information about the disease status.

    FAQs on CD 20, Flow Cytometry Test in Mumbai

    The cost of the CD20 test in Mumbai is ₹2520. This fee covers a convenient home sample collection, which will be completed within 60 minutes of booking. The results will be delivered within 99 hours after the sample is collected.

    Yes, Orange Health Labs provides home sample collection services for the CD20 test in Mumbai. A professional eMedic will arrive at your doorstep within 60 minutes after you book the test.

    The CD20 test is crucial for identifying and monitoring B-cell disorders like lymphoma, leukaemia, and certain immune-related conditions by evaluating the CD20 protein on B lymphocytes.

    No fasting is needed before taking the CD20 test.

    Booking a CD20 test in Mumbai with Orange Health Labs is simple if you follow these steps:

    Search for the Test: Locate the “CD20 test” option and choose Orange Health Labs from the results.

    Confirm Your Booking: Provide the necessary details and pick a convenient time and place for sample collection.

    Sample Collection: A trained eMedic will visit your home to collect your blood sample at the scheduled time.

    Results Delivery: The sample will be tested at our NABL-accredited, ICMR-approved lab, and the results will be delivered via email or WhatsApp within 99 hours.

    The normal range for a CD20 test is 5.0–22.3% for the CD20 cell percentage and 74.4–441.1 cells/µL for the absolute CD20 count.

    You can receive the test results within 99 hours after your sample has been collected.

    The frequency of taking a CD20 test depends on the nature of your condition, such as lymphoma or leukaemia, and the treatment plan advised by your doctor.

    This test evaluates the percentage of CD20 cells and provides an absolute count of CD20-positive cells among lymphocytes.

    The CD20 test is available across various localities in Mumbai, such as Colaba, Nariman Point, Marine Drive, Malabar Hill, Churchgate, Worli, Dadar, Parel, Byculla, Bandra, Andheri, Juhu, Ghatkopar, Powai, Chembur, Vashi, Belapur, Santacruz, Khar, Versova, Lokhandwala, Goregaon, Borivali, Kandivali, Mulund, Bhandup, Kurla.

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    References

    1. The Evaluation of CD3, CD 5, CD10, CD 19, and CD20 Markers in the Differential Diagnosis of the Lymphoma Subtypes in Sudanese Patients. International Journal of Biomedicine.  Available from:  https://www.researchgate.net/publication/356962786_The_Evaluation_of_CD3_CD_5_CD10_CD_19_and_CD20_Markers_in_the_Differential_Diagnosis_of_the_Lymphoma_Subtypes_in_Sudanese_Patients
    2. Comparative Assessment of Surface CD19 and CD20 Expression on B-Cell Lymphomas from Clinical Biopsies: Implications for Targeted Therapies. Blood.  Available from:  https://ashpublications.org/blood/article/134/Supplement_1/5345/425075/Comparative-Assessment-of-Surface-CD19-and-CD%2020
    3. Diffuse large B-cell lymphoma: reduced CD20 expression is associated with inferior survival.  Available from:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943836/
    4. The regulation and function of CD20: an “enigma” of B-cell biology and targeted therapy. Haematologica.  Available from:  https://www.haematologica.org/article/view/9425
    5. Seegmiller AC, Hsi ED, Craig FE. The current role of clinical flow cytometry in the evaluation of mature B‐cell neoplasms.  Available from:  https://onlinelibrary.wiley.com/doi/full/10.1002/cyto.b.21756
    6. Lee AYS. CD20+ T cells: an emerging T cell subset in human pathology. Inflammation research.  Available from:  https://pmc.ncbi.nlm.nih.gov/articles/PMC9616751/#Sec18