Save Tax with full body checkups starting at ₹ 1099
Orange Health
Search for tests or checkups
 Tests
 Checkups
Support
    Complement 4 (C4) Level119489525% off
    trust markerMins HomeCollection
    trust markerHappyCustomers
    trust markerGoogleRating
    trust markerCertifiedLabs

    What is Complement 4 (C4) Level Test?

    The Complement 4 (C4) test is a blood test that measures the levels of the C4 protein in your blood. C4 is an essential part of the complement system, a network of proteins that supports your immune system in combating infections caused by harmful bacteria and viruses. This system involves nine proteins (C1 through C9) that work together to protect your body from threats. The C4 test is frequently used to assess the immune system’s efficiency and to identify certain medical conditions. Reduced C4 levels might indicate that your immune system is mistakenly attacking healthy tissues, which is common in autoimmune conditions like lupus. It can also be associated with persistent infections, blood disorders leading to rapid red blood cell destruction, malnutrition, liver problems, or sudden unexplained swelling. Conversely, higher C4 levels may suggest ongoing recovery from illness, a favourable response to treatment, or conditions like digestive diseases, lung issues, or specific cancers.

    For a more detailed understanding of your immune status, additional testing may be recommended.

    If you’re in Mumbai, you can book the Complement 4 (C4) test at home for added convenience and faster report delivery.

    Complement 4 (C4) Level Test Parameters

    The Complement 4 (C4) test measures one critical parameter:

    • Levels of C4 complement protein in your blood.

    Complement proteins act as a defense system that protects your body against harmful microorganisms like viruses, bacteria, and other pathogens. Once harmful substances are detected, the complement system activates the immune response and forms the Membrane Attack Complex (MAC). This complex attaches to harmful cells, punching holes in their surface, which leads to their destruction.

    Beyond targeting and breaking apart harmful microorganisms, the complement system plays several additional roles in immune defense. It increases the permeability of blood vessels, enabling white blood cells to leave the bloodstream and reach tissues where infection is present. The system also attracts white blood cells to the site of infection and stimulates phagocytosis, a process where immune cells such as neutrophils and macrophages engulf and destroy harmful invaders. Moreover, the system assists in clearing immune complexes from the bloodstream, preventing complications.

    Of all the complement proteins, C3 and C4 are measured most frequently due to their essential roles in immunity. C4, in particular, is crucial for recognizing and responding to harmful invaders, such as bacteria and viruses, making it indispensable for a well-functioning immune response.

    If doctors suspect an immune-related issue, they may recommend testing for C3 and C4 levels. When these levels are outside the normal range, additional tests, such as those measuring C1 inhibitors, may be conducted to investigate the underlying cause. Comprehensive complement activity tests are also valuable in identifying missing or malfunctioning complement proteins.

    Complement 4 (C4) Level Test Preparation

    Below is an overview of what you should keep in mind for the Complement 4 (C4) test:

    Prerequisites: You are not required to fast or make dietary changes before undergoing the Complement 4 (C4) test.

    Best Time to Get Tested: There is no particular time of the day recommended for the C4 test.

    Who Should Get a C4 Test: The C4 test is advised for individuals experiencing symptoms of autoimmune diseases, such as lupus or chronic kidney conditions, or to assess autoimmune conditions like hepatitis. It is helpful in monitoring ongoing treatments or tracking the progression of these conditions.

    Cautions Before Taking C4 Test: You don’t need any special preparations or restrictions before taking the C4 test.

    Why Take the Complement 4 (C4) Level Test?

    The Complement 4 (C4) test may be suggested if you experience symptoms linked to autoimmune conditions, such as lupus or rheumatoid arthritis (RA). Symptoms include:

    • Sensitivity to sunlight that leads to rashes or irritation.

    • Unexplained hair loss or thinning of hair.

    • Joint pain, stiffness, or swelling that restricts movement.

    • Numbness or discolouration in fingers or toes during stress or cold weather.

    • Persistent mild fever lasting for prolonged periods.

    • Butterfly-shaped rash appearing across your cheeks.

    • Mouth sores or ulcers that are difficult to heal.

    • Swelling noticeable around the eyes, hands, or feet.

    • Chronic fatigue or extreme tiredness that interferes with daily activities.

    • Frequent dizziness or persistent headaches.

    • Chest pain when taking deep breaths.

    The C4 test is also valuable for individuals prone to recurrent bacterial or fungal infections. It is useful in assessing the immune system’s strength and detecting issues like kidney dysfunction or chronic hepatitis. If you are diagnosed with an autoimmune disorder, this test can monitor disease progression and evaluate how well treatment plans are working.

    FAQs on Complement 4 (C4) Level Test in Mumbai

    The Complement 4 (C4) test in Mumbai is priced at ₹895. This price includes hassle-free home sample collection, done within 60 minutes of booking confirmation.

    Yes, Orange Health Labs offers home sample collection services in Mumbai for the Complement 4 (C4) test. An eMedic will visit your home within 60 minutes of your test booking, based on slot availability.

    The Complement 4 (C4) test is essential for diagnosing autoimmune diseases, monitoring disease progress, and assessing immune system activity, particularly in conditions like lupus or RA.

    No fasting is required for the Complement 4 (C4) test. If your doctor provides specific instructions, follow them carefully for accurate results.

    Here’s the process to book a Complement 4 (C4) test at Orange Health Labs:

    Locate the test : Visit the Orange Health website or app to find the C4 test.

    Complete your booking : Fill in the required details, choose a suitable time slot, and confirm your test.

    Sample collection : A professional eMedic will collect your sample from your home after the test is confirmed.

    Laboratory testing : Your sample will be processed in an ICMR-approved and NABL-certified laboratory.

    Get your report : The results will be shared via email, WhatsApp, or through the Orange Health app within 80 hours.

    Normal Complement 4 (C4) levels generally range from 10 to 40 mg/dL, but slight variations may occur depending on the specific laboratory and testing techniques employed.

    After scheduling the C4 test, a trained eMedic will collect your blood sample from your home within 60 minutes. Once the sample is processed at the lab, you will receive the report within 80 hours.

    The frequency of taking the C4 test depends on your doctor’s recommendations, your ongoing health conditions, and your treatment progress.

    The C4 test specifically evaluates the level of C4 complement protein in the blood, which is an important component of the immune system.

    Orange Health Labs offers home sample collection for the C4 test in several localities across Mumbai, including Colaba, Nariman Point, Marine Drive, Malabar Hill, Churchgate, Worli, Dadar, Parel, Byculla, Bandra, Andheri, Juhu, Ghatkopar, Powai, Chembur, Vashi, Belapur, Santacruz, Khar, Versova, Lokhandwala, Goregaon, Borivali, Kandivali, Mulund, Bhandup, Kurla.

    The Orange Health Experience

    Choose precision
    Not a pilot, just as precise
    No more painful pricks
    Trust our fully automated and certified labs
    Customers love us

    Choose precision

    On time, every time!

    • 98% on time collections with a 60 minutes promise
    • 99% reports are delivered on time within 6 hours

    Not a pilot, just as precise

    Meet our expert eMedics!

    • Hygienic, well groomed, and professional eMedics
    • With over 100 hours of training

    No more painful pricks

    Experience painless testing!

    • Our eMedics are trained for a single, painless prick.
    • Don’t believe us? We asked our customers and here is what they said - 98% of customers experienced no pain during sample collection!
    • The most organised sample collection box and experience

    Trust our fully automated and certified labs

    For accurate testing

    • Certified labs
    • eQAS partnership with AIIMS and CMC Vellore
    • We have our own fully automated labs in all 4 cities we are available in

    Customers love us

    The highest rated lab!

    • Google rating: 4.9/5 (16000+ reviews)
    • 1 million+ customers tested
    4.9
    Google Rating

    Highest Rated Diagnostic Lab

    Payment & Refund Policy

    • We do not accept cash payments
    • All modes of online payment are accepted
    • Refunds will be credited back to the source of payment within 3 hours of order cancellation.

    References

    1. Clinic C. C4 Complement Blood Test.  Available from:  https://my.clevelandclinic.org/health/diagnostics/c4-complement-blood-test
    2. Complement C4 (Blood).  Available from:  https://www.urmc.rochester.edu/encyclopedia/content?contenttypeid=167&contentid=complement_c4_blood
    3. Complement | Pathology Tests Explained.  Available from:  https://www.pathologytestsexplained.org.au/ptests-pro.php?q=Complement#more-information
    4. Wang H, Liu M. Complement C4, Infections, and Autoimmune Diseases. Frontiers in Immunology.  Available from:  https://pmc.ncbi.nlm.nih.gov/articles/PMC8317844/