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    What is Rubella antibody IgG Test?

    The Rubella Antibody IgG test plays a vital role in assessing immunity to the rubella virus (RuV). Rubella, commonly referred to as German measles, is a viral infection that spreads easily and is caused by the RuV virus. The infection typically results in a mild fever and a rash that starts on the face and spreads to the rest of the body. While rubella may seem harmless, it poses a significant risk to unborn babies if contracted during pregnancy. Pregnant women are particularly at risk as rubella can cause congenital rubella syndrome (CRS) or even miscarriage. CRS, which often occurs during the first trimester, can lead to serious birth defects such as hearing loss, vision issues like cataracts, and heart defects.

    The Rubella IgG test checks for the presence of IgG antibodies, which are produced following infection or vaccination and provide long-lasting immunity. The rubella vaccine, administered as part of the MMR (measles, mumps, rubella) vaccination, offers robust protection against rubella. For women looking to conceive, it is important to confirm immunity as rubella during pregnancy can result in serious harm to the unborn child. Routine testing for rubella antibodies is advised for those planning to have children or who are unsure of their vaccination status.

    If you're in Mumbai and want to check your immunity to rubella, you can conveniently schedule a Rubella Antibody IgG test from home to ensure you’re immune.

    Rubella antibody IgG Test Parameters

    The Rubella IgG test evaluates the levels of IgG antibodies that target the rubella virus.

    Typically, rubella IgG antibodies appear around the fourth day following the onset of a rash and peak within two weeks. These antibodies persist throughout life, indicating previous exposure or vaccination against rubella. For individuals who may have been recently exposed to rubella, rubella-specific IgG antibodies are instrumental in confirming immunity and diagnosing infection. After childbirth, a four-fold or greater increase in rubella-specific IgG antibodies suggests infection or re-infection. For those pregnant and exposed to rubella, measuring rubella-specific IgG antibodies is critical in evaluating immunity.

    In cases of congenital rubella, rubella-specific IgG antibodies in a child help confirm infection by observing their persistence or increase during the first six to 12 months. The detection of rubella-specific IgG antibodies serves as a reliable marker of both immunity and recent infection, making the test important for rubella protection.

    Rubella antibody IgG Test Preparation

    If you're preparing for a Rubella IgG test from home, here are some things you should be aware of:

    • Prerequisites

    There is no need to fast before taking the Rubella IgG test.

    • Best Time to Get Tested

    To detect IgG antibodies effectively, the test should be taken four days after the rash appears. Consult your doctor to ensure the timing is right for you.

    • Who Should Get a Rubella IgG Test?

    This test is recommended for women who are pregnant or planning to become pregnant to check their rubella immunity. It is also useful for individuals showing rubella symptoms, those who may have been exposed to the virus, or those who want to confirm if they’ve had the vaccine or a past infection.

    • Cautions Before Taking a Rubella IgG test

    Make sure to let your doctor know if you've had the rubella vaccine before, as this information can help in interpreting the test results accurately.

    Why Take the Rubella antibody IgG Test?

    The Rubella IgG test serves several key purposes in detecting immunity and recent infection:

    To Evaluate Immunity in Pregnant or Potential Mothers: Pregnant women, or those hoping to conceive, undergo this test to confirm if they have immunity to rubella. Immunity is vital for protecting both the mother and foetus from conditions like congenital rubella syndrome.

    To Diagnose Recent or Active Rubella Infections: If someone displays symptoms of a viral infection, this test can help determine if rubella is the cause. IgM antibodies point to a recent infection, while IgG antibodies suggest past immunity or vaccination.

    To Confirm Immunity from Vaccination: This test helps verify whether a person has acquired immunity from a rubella vaccine. Detecting rubella-specific IgG antibodies means the person is protected, either from past infection or vaccination.

    To Screen for Congenital Rubella in Infants: In cases where newborns have birth defects, this test helps determine if congenital rubella is responsible. Early diagnosis can lead to better management and care for the infant.

    For Healthcare Workers Dealing with Pregnant Patients: Medical professionals working with pregnant women might need this test to confirm rubella immunity. If they are found to lack immunity, vaccination may be suggested to protect their patients from potential complications.

    Rubella antibody IgG Test Results and Interpretation

    Rubella-specific IgG antibodies provide key insights into whether a person has immunity through previous infection or vaccination, or if they remain susceptible to rubella. Below is a table summarizing the test results:

    ParameterBiological ReferenceInterpretation
    Rubella Antibody IgG TestNegative: <10 IU/mL Equivocal: 10-14 IU/mL Positive: => 15The Rubella IgG test is used to diagnose rubella infection and assess immunity status. A positive IgG result usually indicates immunity, either from past infection or vaccination. Follow-up testing after 3 weeks to monitor an increase in IgG levels can confirm an ongoing infection. A stable IgG level or no rise doesn’t completely rule out infection. A negative result suggests no prior exposure to rubella.

    Please Note: For those vaccinated, the rubella virus can remain in respiratory secretions for up to 4 weeks post-vaccination, with antibodies persisting for at least 16 years and potentially for life in about 95% of cases. In congenital rubella, antibodies might disappear by age 3-4, so a negative result in older children doesn’t definitively exclude congenital rubella.

    FAQs on Rubella antibody IgG Test in Mumbai

    In Mumbai, the Rubella IgG test costs ₹900. This includes complimentary home sample collection, which will take place within 60 minutes after booking. Results are available within 73 hours after the sample is collected.

    Yes, home sample collection is provided for the Rubella IgG test in Mumbai. Once you book the test, an eMedic will arrive at your location within 60 minutes to collect the sample.

    The Rubella IgG test is performed to assess immunity to the rubella virus, either from previous vaccination or past infection. It is especially crucial for women who are pregnant or planning pregnancy and for healthcare workers who are in close contact with pregnant patients.

    Fasting is not necessary before taking the Rubella IgG test.

    To schedule a Rubella IgG test with Orange Health Labs in Mumbai, follow these steps:

    Search for the Test: Look for "Rubella IgG test in Mumbai" or "Rubella IgG test at home" and select Orange Health Labs from the results.

    Book the Test: Check the test details and book a convenient time for sample collection.

    Sample Collection: A certified eMedic will visit your location to collect the sample.

    Sample Processing: Your sample will be processed at an ICMR-approved, NABL-accredited laboratory.

    Receive Results: Test results will be sent via email or WhatsApp within 73 hours and can be viewed in our app.

    A positive Rubella IgG result typically signifies immunity from prior infection or vaccination. This usually suggests that the individual has been previously exposed to the virus and developed immunity. A negative result indicates no previous exposure to rubella.

    After booking, an eMedic will collect your sample within 60 minutes. The results are typically available within 73 hours.

    The frequency of the Rubella IgG test depends on your specific health situation. For women planning pregnancy or with potential rubella exposure, your doctor will recommend when the test should be repeated.

    The Rubella IgG test evaluates the levels of IgG antibodies in your blood, which indicate immunity to the rubella virus either from a past infection or vaccination.

    Fasting is not required before taking the Rubella IgG test.

    Orange Health offers home sample collection for the Rubella IgG test across various locations in Mumbai. You can book a test from areas like Colaba, Nariman Point, Marine Drive, Malabar Hill, Churchgate, Worli, Dadar, Parel, Byculla, Bandra, Andheri, Juhu, Ghatkopar, Powai, Chembur, Vashi, Belapur, Santacruz, Khar, Versova, Lokhandwala, Goregaon, Borivali, Kandivali, Mulund, Bhandup, Kurla.

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    References

    1. Serology Testing for Rubella [Internet]. Rubella (German Measles, Three-Day Measles). CDC. 2024  Available from:  https://www.cdc.gov/rubella/php/laboratories/serology-testing.html
    2. Rubella (German Measles): Symptoms, Treatment & Prevention [Internet]. Cleveland Clinic. 2023  Available from:  https://my.clevelandclinic.org/health/diseases/17798-rubella
    3. Rubella Test [Internet]. Children’s Hospital at Montefiore Einstein (CHAM). 2024  Available from:  https://www.cham.org/HealthwiseArticle.aspx?id=hw5576#hw5579
    4. Malliany Camejo Leonor, Mendez MD. Rubella [Internet]. Nih.gov. StatPearls Publishing; 2023  Available from:  https://www.ncbi.nlm.nih.gov/books/NBK559040/
    5. Rubella IgG antibodies [Internet]. Gloucestershire Hospitals NHS Foundation Trust. ; 2024  Available from:  https://www.gloshospitals.nhs.uk/our-services/services-we-offer/pathology/tests-and-investigations/rubella-igg-antibodies/