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    Acetyl Choline Receptor Binding antibody5127363029% off
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    What Is the Acetyl Choline Receptor Binding antibody Test?

    The Acetylcholine Receptor (AChR) Antibody test detects antibodies that attack acetylcholine receptors, which are integral to the nerve-to-muscle signalling process. Acetylcholine activates muscle receptors, prompting contractions. In the case of myasthenia gravis (MG), an autoimmune disorder, the immune system produces abnormal AChR antibodies, disrupting normal muscle function and leading to weakness and fatigue.

    This test is valuable for diagnosing neuromuscular diseases related to acetylcholine receptors. It is particularly useful when symptoms like muscle weakness, difficulty speaking, drooping eyelids (ptosis), or breathing difficulties suggest MG, but additional confirmation is required. It also plays an important role in tracking the effectiveness of treatments for conditions such as thymoma and MG, as successful therapy may result in decreased antibody levels.

    If you are residing in Hyderabad, you can easily schedule an Acetylcholine Receptor Antibody test at home as per your convenience.

    Acetyl Choline Receptor Binding antibody Test Parameters

    The AChR antibody test is used to measure auto-antibodies that target acetylcholine receptors in the bloodstream.

    Acetylcholine is responsible for muscle contraction, but in myasthenia gravis (MG), the production of the AChR protein antibodies interfere with its normal function. As AChR are responsible for transmitting signals from the nerves to muscles, these autoantibodies disrupt neuromuscular activity by blocking, damaging, or changing the acetylcholine receptors at the neuromuscular junction. These antibodies are typically found in 85-90% of individuals with generalized myasthenia gravis.

    Acetyl Choline Receptor Binding antibody Test Preparation

    Preparation for the AChR antibody test is easy and here’s what you should know:

    • Prerequisites: No special preparation like fasting is required.

    • Best Time to Get Tested: You can take the AChR Antibody test at any time throughout the day.

    • Who Should Get an Acetylcholine Receptor Antibody Test?: This test is particularly helpful for those showing symptoms of myasthenia gravis, such as muscle weakness, drooping eyelids, difficulty swallowing, or issues with speaking. It’s also recommended for individuals suspected of having an autoimmune neuromuscular disorder or a thymoma.

    • Cautions Before Taking an Acetylcholine Receptor Antibody Test: Certain medications, such as muscle relaxants or anaesthetics, may influence the results. Be sure to disclose any medications you are currently using to your doctor.

    Why Take the Acetyl Choline Receptor Binding antibody Test?

    The AChR Antibody test is key in diagnosing Myasthenia Gravis (MG), an autoimmune disorder that affects the muscles and nerves. Timely testing helps in better managing the disorder and improving the patient’s quality of life. It is usually recommended when a person exhibits symptoms such as:

    • Eyelid drooping (ptosis)

    • Muscle weakness, particularly in the legs, arms, neck, and fingers

    • Trouble speaking

    • Difficulty with swallowing and chewing

    • Breathing problems

    • Unsteady walking

    FAQs on Acetyl Choline Receptor Binding antibody Test in Hyderabad

    The Acetylcholine Receptor (AChR) Antibody test cost in Hyderabad is ₹3630, which includes home sample collection within 60 minutes of booking, and HYDivering test results online within 132 hours after sample collection.

    Yes, with Orange Health Labs, home sample collection for the AChR Antibody test is available within 60 minutes of booking. A trained eMedic will visit your chosen location to collect the sample.

    The Acetylcholine Receptor Antibody test diagnoses myasthenia gravis by detecting the presence of antibodies that interfere with neuromuscular communication. It also helps diagnose conditions other conditions like thymoma and monitor treatment response.

    No, fasting is not required for the Acetylcholine Receptor Antibody test.

    You can easily book the test with Orange Health Labs by following these steps:

    • Search & Select: Look for the "Acetylcholine Receptor Antibody test" and select Orange Health Labs.

    • Confirm the Appointment: Enter your personal details, select your location, and choose a convenient time for sample collection.

    • Sample Collection: A trained eMedic will collect the sample from your selected location.

    • Laboratory Testing: The sample will be analysed at an ICMR-approved and NABL-accredited laboratory.

    • Results: You will receive your results via email or WhatsApp within 132 hours.

    Normally, Acetylcholine Receptor Antibody levels are below 0.05nmol/L. Low or undetectable antibody levels are within the normal range, but higher values may signal the presence of myasthenia gravis or other neuromuscular disorders. Your doctor will interpret the results, taking your medical history and symptoms into account.

    The results of this test are usually available within 132 hours of sample collection.

    The frequency of your tests will be based on what your doctor recommends. This test is generally conducted if myasthenia gravis is suspected or to evaluate the progression of the disease and the effectiveness of treatment. Your doctor will determine if additional tests are needed depending on how your condition evolves.

    The test assesses for the presence of and measures the levels of acetylcholine receptor antibodies in the blood, which are involved with blocking the acetylcholine receptors at the neuromuscular junction.

    With Orange Health Labs, you can conveniently undergo the Acetylcholine Receptor Antibody test in the comfort of your home or office. You can request sample collection service at various localities in Hyderabad, including Banjara Hills, Jubilee Hills, Gachibowli, Madhapur, Hitech City, Kondapur, Begumpet, Somajiguda, Ameerpet, Panjagutta, Kukatpally, Miyapur, Manikonda, Secunderabad, Tarnaka, Abids, Koti, Mehdipatnam, Dilsukhnagar, Uppal, LB Nagar, Nallagandla, Nizampet, Attapur, Malkajgiri.

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    References

    1. Acetylcholine Receptor Antibody (Blood) - Health Encyclopedia - University of Rochester Medical Center.  Available from:  https://www.urmc.rochester.edu/encyclopedia/content?contenttypeid=167&contentid=acetylcholine_receptor_antibody_blood
    2. Acetylcholine receptor antibody: MedlinePlus Medical Encyclopedia.  Available from:  https://medlineplus.gov/ency/article/003576.htm
    3. Acetylcholine Receptor Antibody.  Available from:  https://www.ucsfhealth.org/medical-tests/acetylcholine-receptor-antibody
    4. Journal of Neurology Neurosurgery & Psychiatr.  Available from:  https://pmc.ncbi.nlm.nih.gov/articles/PMC490626/
    5. ‌Acetylcholine receptor antibody Information | Mount Sinai - New York.  Available from:  https://www.mountsinai.org/health-library/tests/acetylcholine-receptor-antibody