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    What Is the Angiotensin Converting Enzyme (ACE) Test?

    The ACE test is a blood test used to measure the concentration of angiotensin-converting enzyme (ACE), a protein produced by the cells lining the blood vessels, which helps regulate blood pressure. When ACE levels are unusually high, it may indicate a condition known as sarcoidosis. This disease causes the formation of granulomas—clusters of immune cells—in various organs, especially the lungs, which can lead to health problems. High ACE levels are found in around 50% to 80% of individuals with active sarcoidosis. If a doctor suspects that sarcoidosis is the cause of symptoms like a long-lasting cough, shortness of breath, or joint pain, they may recommend the ACE test.

    Elevated ACE levels are also associated with other conditions such as tuberculosis and exposure to specific chemicals. If high ACE levels are found, additional tests may be necessary to identify the precise cause.

    While ACE is naturally present in the body, ACE inhibitors, medications used to lower blood pressure by blocking ACE, may affect the accuracy of the test results.

    If you’re in Hyderabad and experiencing symptoms like a persistent cough, breathlessness, or joint pain, it may be worth considering an ACE test. It can help detect conditions such as sarcoidosis.

    Angiotensin Converting Enzyme (ACE) Test Parameters

    The Angiotensin Converting Enzyme (ACE) test measures the levels of ACE in the blood.

    ACE is a specialised protein that plays a vital role in regulating blood pressure. It works by converting angiotensin I into angiotensin II, causing blood vessels to narrow and raising blood pressure. While most ACE is concentrated in the lungs, it can also be found in other parts of the body. Individuals under the age of 20 typically have higher ACE levels, but as people grow older, these levels naturally decrease and stabilise.

    ACE is also produced by particular cells when the body experiences infection or inflammation. These cells are part of the immune system and form small clusters called granulomas. Granulomas are often present in conditions like sarcoidosis, where they are mainly located in the lungs and other organs.

    Angiotensin Converting Enzyme (ACE) Test Preparation

    When scheduling an Angiotensin Converting Enzyme test, please note the following:

    Prerequisites Fasting is not required for the test.

    Best Time to Take the Test You can take the test at any time of the day based on your personal schedule.

    Who Should Get an Angiotensin Converting Enzyme Test? The test is generally recommended for individuals experiencing unexplained shortness of breath, a persistent cough, joint pain, or unexplained changes in weight, as these may indicate conditions like sarcoidosis or other related health issues.

    Cautions Before Taking Angiotensin Converting Enzyme Test There are no special precautions necessary before taking the Angiotensin Converting Enzyme test.

    Why Take the Angiotensin Converting Enzyme (ACE) Test?

    The ACE test is used to detect sarcoidosis or other conditions that result in the formation of granulomas. These granulomas can appear in various organs, leading to a variety of symptoms. If you experience any of the following, the ACE test may be of help:

    • A persistent cough, difficulty breathing, or wheezing

    • Extreme tiredness

    • Unexplained weight loss or a lack of appetite

    • Chest pain

    • Joint stiffness or soreness

    • Vision problems

    • Dry mouth

    • Headaches

    • Unexplained skin changes, such as rashes, sores, or hardened areas

    • Fever

    The test is particularly significant for individuals aged 20 to 40, as this group is most commonly affected by sarcoidosis. Additionally, the ACE test can help differentiate sarcoidosis from other conditions that cause granulomas, such as infections.

    For those diagnosed with sarcoidosis and initially presenting with high ACE levels, repeating the test can be valuable in tracking the progress of the disease and evaluating the effectiveness of treatments.

    FAQs on the Angiotensin Converting Enzyme (ACE) Test in Hyderabad

    The Angiotensin Converting Enzyme test in Hyderabad is priced at ₹1232. This fee includes the convenience of home sample collection, which will take place within 60 minutes following booking confirmation. You can expect to receive the results within 84 hours after the sample is collected.

    Yes, Orange Health Labs offers the convenience of at-home sample collection for the Angiotensin Converting Enzyme test at home. A qualified eMedic will arrive at your location within 60 minutes of your booking, based on slot availability.

    The Angiotensin Converting Enzyme test measures the concentration of ACE in the blood, which can assist in diagnosing conditions such as sarcoidosis, lung diseases, or liver problems. Increased ACE levels are frequently associated with conditions that cause inflammation in the body.

    Fasting is usually not needed before an ACE test, though it’s important to follow any particular guidance from your doctor.

    Booking the Angiotensin Converting Enzyme test is easy—just follow these steps: • Locate the test: Head to the Orange Health website and select the Angiotensin Converting Enzyme test. • Confirm your appointment: Enter your details, select a preferred time, and confirm your booking. • Sample collection: After confirming your booking, a skilled eMedic will come to your location to collect the sample. • Laboratory processing: Your blood sample will be processed at a certified, NABL-accredited lab approved by the ICMR. • Receive your results: The results will be shared with you via email or WhatsApp within 84 hours of collection and will also be accessible via the Orange Health app.

    The usual range for normal ACE levels in the blood is between 12 and 68 units per litre (u/L).

    Once your Angiotensin Converting Enzyme test is booked, an eMedic will visit your location and collect the sample within 60 minutes. Results will be delivered within 84 hours after the sample collection.

    The need for repeated Angiotensin Converting Enzyme tests is based on your health condition and personal situation. Consult your doctor for further guidance.

    The Angiotensin Converting Enzyme test assesses just one parameter – the amount of angiotensin-converting enzyme in your blood.

    Orange Health offers home sample collection for the Angiotensin Converting Enzyme test in multiple locations throughout Hyderabad, including areas such as Banjara Hills, Jubilee Hills, Gachibowli, Madhapur, Tarnaka, Abids, Koti, Mehdipatnam, Dilsukhnagar, Uppal, LB Nagar, Nallagandla, Nizampet, Attapur, Hitech City, Kondapur, Begumpet, Somajiguda, Ameerpet, Panjagutta, Kukatpally, Miyapur, Manikonda, Secunderabad, and Malkajgiri.

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    • We do not accept cash payments
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    References

    1. Angiotensin converting enzyme (ACE) | Pathology Tests Explained [Internet].  Available from:  https://www.pathologytestsexplained.org.au/ptests-pro.php?q=ACE+%28Angiotensin+converting+enzyme%29
    2. Angiotensin Converting Enzyme (Blood) [Internet].  Available from:  https://www.urmc.rochester.edu/encyclopedia/content?ContentTypeID=167&ContentID=angiotensin_converting_enzyme_blood
    3. Kahkouee S, Samadi K, Alai A, Abedini A, Rezaiian L. Serum ACE Level in Sarcoidosis Patients with Typical and Atypical HRCT Manifestation. Polish Journal of Radiology [Internet].  Available from:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036380/