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    Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA2924262510% off
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    What Is Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test?

    The Anti Neutrophil Cytoplasmic Antibody (ANCA) test is a blood test that checks for proteins produced by the immune system. Normally, these proteins fight infections; however, sometimes they wrongly attack healthy white blood cells like neutrophils and monocytes.

    This test helps diagnose ANCA-associated vasculitis, a condition that causes inflammation in blood vessels. Inflamed blood vessels can become weak, narrow, or blocked, affecting different organs such as the eyes, kidneys, skin, and lungs. Early symptoms include tiredness, fever, weight loss, and general body pain. If left untreated, the condition can lead to serious organ damage.

    The two main proteins linked to ANCA-associated vasculitis are:

    • Myeloperoxidase (MPO): Most common in microscopic polyangiitis (MPA), which affects smaller blood vessels.

    • Proteinase 3 (PR3): Frequently found in granulomatosis with polyangiitis (GPA), which mainly involves the lungs and sinuses.

    Other tests such as PR3 ANCA, kidney function tests, inflammation markers, and full blood counts may be required to confirm the diagnosis and monitor treatment.

    If you are in Hyderabad, you can choose to have the Anti Neutrophil Cytoplasmic Antibody (ANCA) test at home for convenience, with quick sample collection and result delivery.

    Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test Parameters The Anti Neutrophil Cytoplasmic Antibody (ANCA) test is a blood test that detects autoantibodies, specifically PR3 and MPO, which can attack healthy cells by mistake.

    These autoantibodies affect two key proteins:

    cANCA (cytoplasmic ANCA)

    Targets PR3, which is involved in blood cell production and programmed cell death.

    pANCA (perinuclear ANCA)

    Attacks MPO, an important protein that helps fight infections.

    The presence of ANCAs activates neutrophils, a type of white blood cell. This causes the release of chemicals that trigger inflammation, swelling, and damage to blood vessels. Organs like the lungs, kidneys, and skin can be affected. As neutrophils pass through blood vessel walls, they release even more chemicals, making the inflammation and tissue damage worse.

    Although ANCA, PR3, and MPO levels can rise and fall, some people continue to produce these autoantibodies even when tests don’t detect them. A positive ANCA test is often linked to vasculitis but can also occur in conditions such as rheumatoid arthritis, inflammatory bowel disease, and infections like endocarditis or respiratory infections. Some medications may also cause a positive result.

    Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test Preparation

    If you are preparing for the Anti Neutrophil Cytoplasmic Antibody (ANCA) test at home, here’s what you need to keep in mind:

    • Prerequisites: No special preparations are required, and you do not need to fast before the test.

    • Best Time to Get Tested: You can take the ANCA test at any time of the day that works best for you.

    • Who Should Get an Anti Neutrophil Cytoplasmic Antibody (ANCA) Test? If you have unexplained fatigue, fever, weight loss, joint pain, or symptoms affecting your lungs, kidneys, skin, or nervous system, this test can help check for autoimmune vasculitis.

    • Cautions Before Taking an Anti Neutrophil Cytoplasmic Antibody (ANCA) Test: There are no specific precautions to follow before taking the ANCA test.

    Why Take the Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test?

    Your doctor may recommend the Anti Neutrophil Cytoplasmic Antibody (ANCA) test if you have:

    • Ongoing unexplained symptoms like fatigue, fever, night sweats, joint pain, muscle aches, or weight loss.

    • Problems affecting different parts of the body, including:

      • Eyes, ears, and nose: Vision problems, frequent sinus infections, or hearing issues.

      • Skin: Bruising, rashes, or itching.

      • Lungs: Shortness of breath or coughing up blood.

      • Kidneys: Blood or protein detected in the urine.

      • Nerves: Tingling, numbness, or sharp pain.

      • Stomach and intestines: Abdominal pain, diarrhoea, or vomiting blood.

    • Suspected autoimmune vasculitis, including conditions like GPA or MPA.

    • Symptoms of inflammatory bowel disease (IBD), such as diarrhoea, bloody stools, or persistent fever.

    • Routine check-ups to monitor an existing autoimmune vasculitis diagnosis.

    The ANCA test is essential for detecting vasculitis in its early stages, helping prevent serious organ damage and improving long-term management.

    FAQs on Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test in Hyderabad

    The cost of the Anti Neutrophil Cytoplasmic Antibody (ANCA) test in Hyderabad is ₹2625. This includes a swift and convenient home sample collection, carried out within 60 minutes of scheduling. Orange Health Labs provides test results within 72 hours after sample collection.

    Yes, Orange Health Labs provides an easy and efficient home sample collection service for the Anti Neutrophil Cytoplasmic Antibody (ANCA) test. A trained eMedic professional will reach your home within 60 minutes after booking to collect your blood sample.

    The Anti Neutrophil Cytoplasmic Antibody (ANCA) test is designed to detect autoimmune conditions like vasculitis. It identifies specific autoantibodies in the blood that can trigger inflammation and damage to blood vessels and organs.

    No, there is no need to fast before undergoing the Anti Neutrophil Cytoplasmic Antibody (ANCA) test.

    Scheduling an Anti Neutrophil Cytoplasmic Antibody (ANCA) test with Orange Health Labs is simple:

    • Search for the Test: Type "Anti Neutrophil Cytoplasmic Antibody (ANCA) Test" in your browser and select Orange Health Labs.

    • Confirm Your Booking: Enter your details, select your location, and choose a time for the sample collection.

    • Sample Collection: A trained eMedic professional will visit your home or location to collect your blood sample.

    • Testing & Results: The sample will be processed at our NABL-accredited, ICMR-approved lab, and results will be sent via email or WhatsApp within 72 hours.

    If the ANCA test result is negative, it means no p-ANCA or c-ANCA autoantibodies are detected, which generally excludes autoimmune vasculitis. A positive result, however, indicates their presence and requires further tests to determine the underlying condition.

    Once the sample is collected, the Anti Neutrophil Cytoplasmic Antibody (ANCA) test results are usually available within 72 hours.

    The frequency of the Anti Neutrophil Cytoplasmic Antibody (ANCA) test is entirely dependent on your medical condition and should be decided by your doctor.

    The ANCA test identifies specific antibodies, including p-ANCA, c-ANCA, MPO, and PR3.

    The Anti Neutrophil Cytoplasmic Antibody (ANCA) test is offered in several parts of Hyderabad, including but not restricted to Banjara Hills, Jubilee Hills, Gachibowli, Madhapur, Hitech City, Kondapur, Begumpet, Somajiguda, Ameerpet, Panjagutta, Kukatpally, Miyapur, Manikonda, Secunderabad, Tarnaka, Abids, Koti, Mehdipatnam, Dilsukhnagar, Uppal, LB Nagar, Nallagandla, Nizampet, Attapur, Malkajgiri.

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    References

    1. Antineutrophil Cytoplasmic Antibodies (ANCA) Test: MedlinePlus Medical Test.  Available from:  https://medlineplus.gov/lab-tests/antineutrophil-cytoplasmic-antibodies-anca-test/
    2. Antineutrophil Cytoplasmic Antibodies (ANCA) Test: What It Is. 3. Antineutrophil cytoplasmic antibodies (ANCA) | Pathology Tests Explained. 4. Khalid N, Aeddula NR. Antinuclear Cytoplasmic Antibody [Internet]. PubMed. Treasure Island (FL). 5. The value of anti-neutrophil cytoplasmic antibodies (ANCA) testing for the diagnosis of ANCA-associated vasculitis, a systematic review and meta-analysis.  Available from:  https://my.clevelandclinic.org/health/diagnostics/22512-anca-test