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    Anti Smooth Muscle antibody (Anti-SMA) (IFA)2626200024% off
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    What is Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test?

    The Anti Smooth Muscle Antibody (ASMA) test is a diagnostic blood test used to detect smooth muscle antibodies (SMAs) in the body. These autoantibodies are mistakenly produced by the immune system and attack healthy liver cells, leading to inflammation and damage. This test is an important tool in diagnosing autoimmune hepatitis (AIH), a chronic condition where the immune system wrongly targets the liver.

    In a healthy immune system, the body fights off harmful invaders such as bacteria and viruses. However, in autoimmune diseases like AIH, the immune system mistakenly produces autoantibodies, such as ASMAs, that attack the body’s tissues. If left unmanaged, AIH can cause serious liver complications, including cirrhosis. Treatment usually involves immunosuppressive medications that reduce immune system activity to prevent further liver damage.

    AIH is classified into two types:

    • Type 1, which is the most frequent form and affects both adults and children, particularly women.

    • Type 2, a rarer form, mainly seen in young girls, is associated with antibodies like LKM-1.

    To confirm AIH, doctors often recommend the ASMA test alongside other autoantibody tests, such as ANA and LKM-1 antibody tests.

    If you're in Hyderabad, you can book this test for home sample collection, ensuring convenience and quick results.

    Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test Parameters

    The Anti-Smooth Muscle Antibody (ASMA) test is used to detect autoantibodies that attack smooth muscle proteins in the blood. These proteins are commonly found in hollow organs such as the stomach, intestines, and blood vessels, but they are also present in large amounts in liver cells. When ASMA levels are elevated, it can indicate autoimmune hepatitis (AIH) or other liver-related disorders.

    This test is essential in determining whether the immune system is wrongly attacking liver tissues. To achieve a clearer diagnosis, ASMA testing is often performed along with ANA and LKM-1 antibody tests.

    There are different methods for detecting ASMA, each providing insight into the specific type and strength of antibodies, which can offer valuable information about liver health. Since its discovery in liver disease patients, ASMA testing has greatly advanced the understanding and management of AIH. Early diagnosis through this test helps prevent serious complications like cirrhosis, liver failure, and permanent liver damage. If ASMA is detected, treatment focuses on immune system regulation to protect liver function.

    Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test Preparation

    To know how to prepare for the Anti-Smooth Muscle Antibody (ASMA) test, check the following:

    • Prerequisites :

    No fasting or prior preparation is needed.

    • Best Time to Get Tested :

    This test can be taken at any time of day.

    • Who Should Get an Anti-Smooth Muscle Antibody Test? :

    Those experiencing liver disease symptoms (such as jaundice, fatigue, and abdominal discomfort) or individuals with irregular liver function test results should take this test to evaluate for autoimmune hepatitis.

    • Cautions Before Taking an Anti-Smooth Muscle Antibody Test :

    There are no specific precautions to follow before taking the test.

    Why Take the Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test?

    If you’re experiencing liver-related symptoms, your doctor may recommend an Anti-Smooth Muscle Antibody (ASMA) test. Symptoms that indicate possible autoimmune hepatitis (AIH) include:

    • Jaundice (yellowing of the skin and eyes)

    • Ongoing fatigue and weakness

    • Frequent nausea or reduced appetite

    • Pain or discomfort in the abdomen

    • Dark urine and light-coloured stools

    • Unexplained joint stiffness or pain

    • Skin issues like rashes, acne, psoriasis, or vitiligo

    Even without obvious symptoms, routine blood tests like a Comprehensive Metabolic Panel (CMP) may show liver function abnormalities, prompting an ASMA test for further investigation. If ASMA is found, additional assessments, including a liver biopsy, may be needed to evaluate the severity of liver damage.

    FAQs on Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test in Hyderabad

    The cost of this test in Hyderabad is ₹2000. This fee includes quick home sample collection, typically within 60 minutes of booking. The test results will be available within 99 hours after sample collection.

    Yes, you can opt for home sample collection for this test through Orange Health Labs. A certified professional will arrive at your location within 60 minutes for sample collection.

    This test helps detect autoimmune hepatitis (AIH) by identifying antibodies that attack smooth muscle proteins in the liver. It also assesses liver damage and can determine whether additional tests like a liver biopsy are necessary.

    No, fasting is not required. The test can be conducted at any time.

    Here’s how you can book an Anti-Smooth Muscle Antibody test with Orange Health Labs in Hyderabad:

    • Step 1: Search for the test online and select Orange Health Labs.

    • Step 2: Provide your contact details, address, and preferred time for sample collection.

    • Step 3: A certified eMedic professional will visit your location and collect the blood sample.

    • Step 4: Your sample will be analyzed at a NABL-certified, ICMR-approved laboratory, and the results will be sent via email or WhatsApp within 99 hours.

    A normal result is negative, meaning no antibodies were found. A positive test suggests an autoimmune response, possibly linked to autoimmune hepatitis or liver conditions.

    You can expect your test results within 99 hours after your sample is collected.

    Your physician will decide if additional tests or repeat testing are required based on your health status and medical evaluation.

    It detects autoantibodies against smooth muscle proteins, which can help in diagnosing liver-related autoimmune diseases.

    The test is available at multiple locations in Hyderabad, including Banjara Hills, Jubilee Hills, Gachibowli, Madhapur, Hitech City, Kondapur, Begumpet, Somajiguda, Ameerpet, Panjagutta, Kukatpally, Miyapur, Manikonda, Secunderabad, Tarnaka, Abids, Koti, Mehdipatnam, Dilsukhnagar, Uppal, LB Nagar, Nallagandla, Nizampet, Attapur, Malkajgiri.

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    References

    1. Smooth Muscle Antibody (SMA) Test: MedlinePlus Medical Test. 2. Anti-smooth muscle antibody - UF Health.  Available from:  https://medlineplus.gov/lab-tests/smooth-muscle-antibody-sma-test/
    2. Zhang WC, Zhao FR, Chen J, Chen WX. Meta-Analysis: Diagnostic Accuracy of Antinuclear Antibodies, Smooth Muscle Antibodies and Antibodies to a Soluble Liver Antigen/Liver Pancreas in Autoimmune Hepatitis.  Available from:  https://pmc.ncbi.nlm.nih.gov/articles/PMC3961308/#s4