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    CD 20, Flow Cytometry5143252051% off
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    What is CD 20, Flow Cytometry Test?

    The CD20 blood test identifies the levels of CD20, a protein found on the surface of B-cells, a specific type of white blood cell. This protein is essential for the immune system, helping in B-cell development and maturity. This test is primarily recommended to diagnose and monitor B-cell-related cancers, including lymphomas.

    Lymphomas are cancers originating in the lymphatic system, a vital part of the body’s immune defense. B-cell lymphomas occur when B-cells turn cancerous. While most B-cells show CD20 on their surface, its expression may differ depending on the type of lymphoma. Some lymphomas may exhibit lower levels of CD20, influencing how effective treatments targeting CD20, like rituximab, can be.

    The CD20 Marker Flow Cytometry test is performed using flow cytometry. This advanced technique measures CD20 expression on B-cells and determines any variations in the protein's behaviour. These findings help in selecting the best treatment for lymphoma patients. For example, if CD20 levels are low or absent, alternative treatments may be considered to ensure better outcomes.

    For residents in Hyderabad, the CD20 test is easily accessible with at-home sample collection services, ensuring convenience and timely delivery of accurate test results.

    CD 20, Flow Cytometry Test Parameters

    The CD20 test measures one specific parameter: the CD20 cell count, which is reported as both an absolute count and a percentage of lymphocytes.

    CD20 is a specific protein found on the surface of B-cells, which are crucial components of the immune system, helping the body in fighting infections. This protein appears during the early stages of B-cell development and is essential for their activation, growth, and eventual maturation. However, as B-cells evolve into plasma cells (their final stage of development), they lose CD20. This unique characteristic makes CD20 an effective marker for studying the progression of B-cell development.

    Although primarily associated with B-cells, CD20 is also present on a smaller subset of T-cells, another key immune cell type. However, its primary function lies in B-cells. The expression levels of CD20 can vary significantly among different B-cell cancers, providing valuable information for personalized treatment strategies. Beyond being a marker, CD20 also plays a regulatory role in B-cell function, particularly in helping calcium enter cells. This calcium influx is vital for enabling B-cells to perform their immune defense tasks efficiently.

    CD 20, Flow Cytometry Test Preparation

    Before scheduling the CD20 test at home, keep in mind the following essential points:

    • Prerequisites

    The CD20 test does not require any special preparation, including fasting.

    • Best Time to Get Tested

    There are no time restrictions for the CD20 test, meaning it can be taken at any convenient hour of the day.

    • Who Should Get a CD20 Test?

    The test is recommended for individuals experiencing symptoms of blood cancers such as lymphoma or leukaemia, as it assists in both diagnosing and managing these conditions.

    • Cautions Before Taking a CD20 Test

    There are no specific precautions to follow before undergoing the CD20 test.

    Why Take the CD 20, Flow Cytometry Test?

    The CD20 test plays a key role in diagnosing and managing certain health conditions, especially B-cell-related disorders like lymphoma.

    • Helps Diagnose Lymphoma : It’s a critical tool for identifying different types of B-cell lymphomas.

    • Supports Treatment Decisions : This test helps to decide whether treatments like rituximab might work for you, tailoring care to your needs.

    • Monitors Disease Progression : It tracks how the disease is developing or responding to treatment, ensuring you stay on the right path.

    • Identifies High-Risk Patients : The test can flag cases that need extra attention by measuring CD20 levels and assessing risks.

    • Checks Treatment Effectiveness : If CD20 levels are low, it might mean the current treatment isn’t working as expected, prompting adjustments.

    • Personalised Treatment Plan : By analysing CD20 levels, treatment plan can be tailored specifically to you, increasing your chances of a better outcome.

    The CD20 test gives valuable information on the disease status to ensure you get the care you need when you need it most.

    FAQs on CD 20, Flow Cytometry Test in Hyderabad

    The cost of a CD20 test in Hyderabad is ₹2520. This fee includes the convenience of home sample collection, which will be completed within 60 minutes of booking. Once the sample is collected, Orange Health Labs ensures that you receive the test results within 99 hours of sample collection.

    Yes, Orange Health Labs offers home sample collection for the CD20 test in Hyderabad. Once your booking is confirmed, a trained eMedic will visit your home to collect the sample within 60 minutes of sample collection.

    The CD20 test helps diagnose and monitor B-cell-related conditions such as lymphoma, leukaemia, and immune system disorders. It measures CD20 protein levels on B lymphocytes.

    No fasting or specific preparation is required for the CD20 test.

    Booking a CD20 test with Orange Health Labs in Hyderabad is a simple process:

    Search for the Test: Look up the “CD20 test” and select the listing for Orange Health Labs.

    Confirm Your Booking: Enter your details, select your preferred time and location for sample collection.

    Sample Collection: A trained eMedic will visit your home to collect your blood sample at the scheduled time.

    Analysis and Results: Your sample will be analysed at our NABL-accredited, ICMR-approved laboratory, and the results will be sent to you via email or WhatsApp within 99 hours.

    The normal levels for the CD20 test are typically between 5.0–22.3% for CD20 cell percentages and 74.4–441.1 cells/µL for absolute CD20 counts.

    The test reports are usually ready within 99 hours after sample collection.

    The frequency of CD20 testing depends on your medical diagnosis, health condition, and the treatment plan recommended by your doctor.

    This test includes the following parameters: the percentage of CD20 cells among lymphocytes and the absolute count of CD20-positive cells.

    Orange Health Labs offers the CD20 test across Hyderabad, including areas like, Banjara Hills, Jubilee Hills, Gachibowli, Madhapur, Hitech City, Kondapur, Begumpet, Somajiguda, Ameerpet, Panjagutta, Kukatpally, Miyapur, Manikonda, Secunderabad, Tarnaka, Abids, Koti, Mehdipatnam, Dilsukhnagar, Uppal, LB Nagar, Nallagandla, Nizampet, Attapur, Malkajgiri.

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    References

    1. The Evaluation of CD3, CD 5, CD10, CD 19, and CD20 Markers in the Differential Diagnosis of the Lymphoma Subtypes in Sudanese Patients. International Journal of Biomedicine.  Available from:  https://www.researchgate.net/publication/356962786_The_Evaluation_of_CD3_CD_5_CD10_CD_19_and_CD20_Markers_in_the_Differential_Diagnosis_of_the_Lymphoma_Subtypes_in_Sudanese_Patients
    2. Comparative Assessment of Surface CD19 and CD20 Expression on B-Cell Lymphomas from Clinical Biopsies: Implications for Targeted Therapies. Blood.  Available from:  https://ashpublications.org/blood/article/134/Supplement_1/5345/425075/Comparative-Assessment-of-Surface-CD19-and-CD%2020
    3. Diffuse large B-cell lymphoma: reduced CD20 expression is associated with inferior survival.  Available from:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943836/
    4. The regulation and function of CD20: an “enigma” of B-cell biology and targeted therapy. Haematologica.  Available from:  https://www.haematologica.org/article/view/9425
    5. Seegmiller AC, Hsi ED, Craig FE. The current role of clinical flow cytometry in the evaluation of mature B‐cell neoplasms.  Available from:  https://onlinelibrary.wiley.com/doi/full/10.1002/cyto.b.21756
    6. Lee AYS. CD20+ T cells: an emerging T cell subset in human pathology. Inflammation research.  Available from:  https://pmc.ncbi.nlm.nih.gov/articles/PMC9616751/#Sec18