Can creatinine levels fluctuate?

Yes, creatinine levels can fluctuate due to factors such as hydration, diet, and physical activity. Temporary increases in creatinine may occur after intense exercise, a high-protein meal, or during dehydration. Minor fluctuations are generally not a cause for concern, but consistent elevations in creatinine levels could indicate kidney dysfunction. If your levels fluctuate, your doctor may recommend follow-up tests to determine if the changes are due to temporary factors or underlying kidney issues.