What are the long-term consequences of high creatinine levels?

If high creatinine levels persist, they may indicate chronic kidney disease (CKD) or other long-term kidney problems. Over time, untreated kidney dysfunction can lead to end-stage renal disease (ESRD), requiring dialysis or a kidney transplant. Persistently elevated creatinine levels can also increase the risk of complications like heart disease, fluid retention, and high blood pressure. Early detection and treatment of elevated creatinine levels are essential to slow the progression of kidney disease and prevent long-term damage.