What is the relationship between creatinine levels and kidney failure?

Elevated creatinine levels are a key indicator of kidney dysfunction and can signal kidney failure if the levels are consistently high. When the kidneys fail to filter waste efficiently, creatinine accumulates in the blood. Kidney failure, also known as end-stage renal disease (ESRD), occurs when kidney function declines to the point where dialysis or a kidney transplant may be needed. Monitoring creatinine levels helps detect worsening kidney function and allows for early interventions to prevent complete kidney failure. After the Test: Interpretation of Results, Management Strategies, and Follow-Up