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    What is the Anti Nuclear Antibody (ANA) (IFA) Test?

    The ANA test, or Anti-nuclear Antibody test, is a blood test that measures the amount and looks into the pattern of specific proteins called antinuclear antibodies in your blood. 2 In normal conditions, these antibodies are produced by the immune system to target harmful invaders like bacteria and viruses and destroy them. However, in some autoimmune diseases, the immune system gets confused and starts attacking the healthy cells in your body instead. Since these antibodies target the nucleus, the central part of the cell, they are called Antinuclear Antibodies.

    The ANA test helps doctors find out if you have an autoimmune disease, such as rheumatoid arthritis or systemic lupus erythematosus (SLE). A diagnosis for autoimmune conditions is made based on the interpretation of this test, your other tests, symptoms, and a physical examination. 2 By examining all this information, doctors can determine if your immune system is mistakenly attacking your body and decide on the best way to treat or manage the disease.

    If you live in Bangalore and are dealing with symptoms such as joint pain, chronic fatigue, or persistent rashes, you should consider getting an ANA test in Bangalore. 1 This test can help detect autoimmune disorders early and allow you to begin the necessary treatment promptly.

    Anti Nuclear Antibody (ANA) (IFA) Test Parameters

    The ANA IFA test looks into two main things: the titre value and the fluorescent pattern.

    Titre Value

    This measures how many antinuclear antibodies (ANAs) are in your blood. To find this, the blood sample is diluted in steps until the antibodies are no longer detectable. The highest level of dilution where antibodies are still found is recorded as the titre. A higher titre suggests more antibodies and a greater possibility of an autoimmune disease.

    Pattern

    The test also checks how these antibodies attach to different parts of the cell using a special dye that makes them glow under a microscope. This glowing pattern helps doctors identify specific autoimmune diseases like lupus, rheumatoid arthritis, or Sjögren’s syndrome. By looking at these patterns, doctors can figure out if more tests are needed to find out which specific antibodies are present.

    This ANA test is done by the Indirect Immunofluorescence (IFA) method, which helps visualise the different patterns of these antibodies and provides important clues for diagnosing autoimmune conditions.

    Anti Nuclear Antibody (ANA) (IFA) Test Preparation

    Before scheduling an ANA test at home, please keep the following points in mind:

    • Prerequisites

    Fasting is not necessary for the ANA test.

    • Best Time to Get Tested

    The ANA test can be scheduled at any time of the day.

    • Who Should Get an ANA Profile Test?

    You might need an ANA test if your doctor suspects you have an autoimmune disorder. This test is done if you have symptoms such as fever, rashes or changes in your skin, extreme tiredness (fatigue), joint pain, stiffness, swelling, or muscle pain. The ANA test checks for specific antibodies in your blood that can help doctors determine if these symptoms are due to an autoimmune disease.

    • Cautions Before Taking ANA Profile Test

    There are generally no precautions or special preparations needed for the ANA test.

    Why Take the Anti Nuclear Antibody (ANA) (IFA) Test?

    The ANA test helps doctors find out if you have certain autoimmune disorders by checking for specific antibodies in your blood. It is used to diagnose conditions like:

    • Systemic Lupus Erythematosus (SLE) : A disease that affects many parts of the body, including joints, skin, and organs.

    • Rheumatoid Arthritis : A condition that mainly affects the joints, causing pain and swelling.

    • Sjögren's Syndrome : A condition that affects the glands that produce tears and saliva.

    • Scleroderma : A rare disease that can affect the skin and organs.

    • Autoimmune Hepatitis : A condition with inflammation in the liver.

    • Addison Disease : A disease that affects the adrenal glands, leading to fatigue and weakness.

    Doctors order the ANA IFA test if you have symptoms like fever, joint pain, rashes, extreme tiredness or muscle pain. The ANA test helps discern if these symptoms are caused by an autoimmune disease by looking for specific antibodies in your blood.

    Anti Nuclear Antibody (ANA) (IFA) Test Results & Interpretation

    FAQs on Anti Nuclear Antibody (ANA) (IFA) Test in Bangalore

    The ANA test price is ₹ 1300. This price includes the quickest home sample collection within 60 of booking, and the reports are available in 59 hours.

    Yes, Orange Health Labs offers home sample collection services for the ANA test in Bangalore. You can have your sample collected at home within 60 minutes of booking, depending on slot availability.

    The ANA test detects antibodies that attack the cell's nucleus. It helps diagnose autoimmune diseases such as lupus and rheumatoid arthritis. A positive result suggests an autoimmune condition.

    No, fasting is not required for the ANA blood test.

    Provided below are the steps to book any blood test or health checkup through our platform:

    • Find the Test : Search for the Antinuclear Antibody/ANA test in Bangalore or at home and click on Orange Health’s page.

    • Review and Verify : Select the test, go over the prerequisites, enter your location, and complete the booking by choosing a time for the sample collection.

    • Collection of Sample : At the appointed time, a trained eMedic will come to your home to get a sample.

    • Lab Processing : The sample will be sent to our ICMR-approved and NABL-accredited laboratory for examination.

    • Receive Results : Your reports will be sent to you via email or WhatsApp within 59 hours, accessible also through our app interface.

    The ANA test results are interpreted as follows: A negative result means you are less likely to have an autoimmune disease. A positive result means these antibodies are present, suggesting a possible autoimmune condition. High levels of antibodies often indicate more severe disease activity and additional tests are needed for a full diagnosis.

    Once you book an ANA test, Orange Health Labs will collect your sample within 60 minutes, with home sample collection typically taking only a few minutes. You can expect to receive your reports online within 59 hours.

    Your doctor will guide you on the frequency of ANA testing based on your specific needs.

    The ANA test measures both the number of antibodies (titre) and their patterns. A low titre suggests fewer antibodies and a lower chance of autoimmune disease, while a high titre indicates a more active autoimmune condition. Various patterns, such as homogeneous or speckled, help doctors diagnose specific autoimmune diseases like lupus or rheumatoid arthritis.

    Orange Health provides the fastest ANA test across Bangalore, which can be done from the convenience of your home. Localities served include but are not limited to Adugodi, Banashankari, Bannerghatta, Basavanagudi, Bellandur, BTM Layout, Chamrajpet, Cottonpet, CV Raman Nagar, Domlur, Electronic City, Frazer Town, Giri Nagar, Hebbal, Hennur, Hosur, HSR Layout, Jakkur, Jalahalli, Jaya Nagar, Kadugodi, Kammanahalli, Kengeri, Koramangala, Mahalakshmi Layout, Madiwala, Magadi Road, Malleshwaram, Marathahalli, Mathikere, Mysore Road, Nagarbhavi, Nandhini Layout, Old Airport Road, Peenya, RT Nagar, Rajaji Nagar, Rajarajeshwari Nagar, Sadashivnagar, Sahakara Nagar, Sanjay Nagar, Sarjapur, Seshadripuram, Shanthi Nagar, Shivaji Nagar, Sri Nagar, Tyagarajnagar, Uttarahalli, Vasanth Nagar, Vidyaranyapura, Vijaya Nagar, Whitefield, Yelahanka, Yeshwantpur.

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    References

    1. Medline Plus. ANA (Antinuclear Antibody) Test: MedlinePlus Medical Test [Internet]  Available from:  https://medlineplus.gov/lab-tests/ana-antinuclear-antibody-test/
    2. Antinuclear Antibodies (ANA) Test [Internet].  Available from:  https://www.columbiadoctors.org/health-library/test/antinuclear-antibodies-ana-test/
    3. Fastest Anti-nuclear Antibody (ANA) (IFA) Test in Bangalore at Best Price + Reports in 6 Hours [Internet].  Available from:  https://www.orangehealth.in/lab-test-bangalore/anti-nuclear-antibody?utm_source=seo_search&utm_medium=google&utm_campaign=seo&utm_term=anti-nuclear-antibody