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    CA 15.3, Breast Cancer Marker2015135033% off
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    What is CA 15.3, Breast Cancer Marker Test?

    The Cancer Antigen (CA) (Breast Cancer Marker) test measures the level of CA 15-3 (Cancer Antigen 15-3) in the blood. It is a glycoprotein that is primarily used as a tumour marker to monitor patients with breast cancer, especially for assessing treatment response, detecting recurrence, and sometimes for early detection. However, it is not used for primary diagnosis due to its limited sensitivity and specificity.

    Individuals with advanced breast cancer who are advised to monitor the progression of the disease can consider scheduling a CA 15.4 (Breast Cancer Marker) test at home.

    CA 15.3, Breast Cancer Marker Test Parameters

    The CA 15.3 (Breast Cancer Marker) test measures the breast cancer marker CA 15.3 levels in the blood.

    CA 15.3 is a protein produced by certain cells, primarily breast cancer cells, and is released into the blood. It is commonly used as a tumour marker to monitor breast cancer progression and response to treatment.

    Elevated levels of CA 15.3 are often associated with advanced or metastatic breast cancer. Other conditions that may cause high CA 15.3 levels include ovarian, lung, or prostate cancers, as well as benign conditions like endometriosis, pelvic inflammatory disease, and benign breast or ovarian diseases. CA 15.3 can also be non-cancerous conditions such as pregnancy, lactation, endometriosis, liver disease, and pelvic inflammatory disease. Limitations of this test include:

    Not Specific

    While CA 15.3 is most commonly associated with breast cancer, it lacks high specificity and sensitivity, meaning other malignancies and non-cancerous conditions may also cause elevated levels.

    Not a Screening Test

    It is not recommended for routine breast cancer screening or as a diagnostic tool. It is mainly useful for monitoring known cancer patients.

    False Negative

    In some cases, CA 15.3 levels may be within the normal range despite the presence of cancer, particularly in early or localised disease.

    CA 15.3, Breast Cancer Marker Test Preparation

    To prepare for the CA 15.3 (Breast Cancer Marker) test, check the following testing pre-requisites:

    • Prerequisites : Fasting is not required before a CA 15.3 (Breast Cancer Marker) test.

    • Best Time to Get Tested : The CA 15.3 (Breast Cancer Marker) test can be conducted at any time that is convenient for you.

    • Who Should Get a CA 15.3 (Breast Cancer Marker) Test? : Testing is recommended for individuals undergoing treatment for advanced or metastatic breast cancer to monitor the treatment response. Those with a history of breast cancer can also take the test to detect potential recurrence.

    • Cautions Before Taking a CA 15.3 (Breast Cancer Marker) Test : Inform your doctor about any ongoing medications or conditions that could influence the test results. It is also important to note that CA 15.3 levels may be elevated in non-cancerous conditions including pregnancy, lactation, and benign breast diseases.

    Why Take the CA 15.3, Breast Cancer Marker Test?

    The CA 15.3 test is valuable in managing breast cancer, particularly for advanced or metastatic cases. Here are some reasons to get tested:

    • Monitor Breast Cancer Treatment : During or after treatment for breast cancer, serial CA 15-3 measurements can help assess how well the treatment is working.

    • Detect Recurrence : Elevated levels in a patient with a history of breast cancer may indicate a recurrence, although confirmation with imaging and biopsy is necessary.

    • Prognostic Role : Some studies suggest that elevated CA 15-3 levels at the time of diagnosis or during treatment can correlate with poorer prognosis, but it should be interpreted with caution.

    • Assess Metastatic Breast Cancer : To monitor the progression of metastatic breast cancer in conjunction with other tests like hormone receptor and HER2 status testing.

    • Support Diagnosis of Metastases : To assist in diagnosing metastatic breast cancer as part of a cost-effective diagnostic approach when combined with imaging and other tumour markers.

    • Guide Disease Management : To provide an understanding of the disease status, enabling timely adjustments to treatment plans.

    FAQs on CA 15.3, Breast Cancer Marker Test in Bangalore

    The CA 15.3 (Breast Cancer Marker) test in Bangalore is priced at ₹1350. This cost includes prompt home sample collection within 60 minutes of booking and delivery of test results within 9 hours of sample collection.

    Yes, Orange Health Labs offers home sample collection for the CA 15.3 (Breast Cancer Marker) Test. A professional eMedic will visit your location within 60 minutes of booking to collect the sample.

    The CA 15.3 test is used to monitor breast cancer progression, assess the effectiveness of treatment, and detect the recurrence of cancer, especially in metastatic cases. It is not suitable for early detection or as a general screening test for breast cancer.

    Fasting is not required for the CA 15.3 test. You can schedule the test at any time that suits you.

    To book a CA 15.3 (Breast Cancer Marker) Test with Orange Health Labs, follow these steps:

    • Search for the Test: Look for the "CA 15.3 (Breast Cancer Marker) Test" and select the Orange Health Labs listing from the available options.

    • Confirm Your Booking: Enter your details, including location and preferred time for sample collection, and finalise the booking.

    • Sample Collection: A trained eMedic from Orange Health Labs will visit your home for sample collection.

    • Analysis of Sample: The collected sample will be analysed at our NABL-accredited, ICMR-approved laboratory.

    • Get Your Results: The test results will be sent to you via email or WhatsApp within 9 hours.

    Normal levels for the CA 15.3 (Breast Cancer Marker) test are typically less than 35U/mL. Elevated levels may indicate breast cancer progression or recurrence. Consult your doctor for proper interpretation of test results.

    Reports for the CA 15.3 test are generally available within 9 hours after the sample collection.

    The frequency of the CA 15.3 test depends on your doctor’s recommendations. It is typically done periodically to monitor the treatment's effectiveness.

    The CA 15.3 (Breast Cancer Marker) Test detects only one parameter: the level of cancer antigen 15-3, a tumour marker associated with advanced breast cancer.

    Orange Health offers a home sample collection for CA 15.3 (Breast Cancer Marker) test at home across several localities in Bangalore, including but not limited to Adugodi, Banashankari, Bannerghatta, Basavanagudi, Bellandur, BTM Layout, Chamrajpet, Cottonpet, CV Raman Nagar, Frazer Town, Giri Nagar, Hebbal, Domlur, Electronic City, Hennur, Hosur, HSR Layout, Jakkur, Jalahalli, Jaya Nagar, Kadugodi, Kammanahalli, Kengeri, Koramangala, Mahalakshmi Layout, Madiwala, Magadi Road, Malleshwaram, Marathahalli, Mathikere, Mysore Road, Nagarbhavi, Nandhini Layout, Old Airport Road, Peenya, RT Nagar, Rajaji Nagar, Rajarajeshwari Nagar, Sadashivnagar, Sahakara Nagar, Sanjay Nagar, Sarjapur, Seshadripuram, Shanthi Nagar, Shivaji Nagar, Sri Nagar, Tyagarajnagar, Uttarahalli, Vasanth Nagar, Vidyaranyapura, Vijaya Nagar, Whitefield, Yelahanka, Yeshwantpur.

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    References

    1. CA 15-3. 2024  Available from:  https://www.urmc.rochester.edu/encyclopedia/content?contenttypeid=167&contentid=ca_15_3
    2. Cancer antigen 15-3 (CA15-3) test [Internet]. Canadian Cancer Society.  Available from:  https://cancer.ca/en/treatments/tests-and-procedures/cancer-antigen-15-3-ca-15-3
    3. Prognostic Impact of Elevation of Cancer Antigen 15-3 (CA15-3) in Patients With Early Breast Cancer With Normal Serum CA15-3 Level.  Available from:  https://pmc.ncbi.nlm.nih.gov/articles/PMC10139845/
    4. CA 15-3. Stanford Healthcare. 5. Qing H. Meng. Chapter 5 - Tumor markers. Self-Assessment Q&A in Clinical Laboratory Science.  Available from:  https://stanfordhealthcare.org/medical-tests/t/tumor-markers/types/ca-15-3.html