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    Anti Smooth Muscle antibody (Anti-SMA) (IFA)2626200024% off
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    What is Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test?

    The Anti Smooth Muscle Antibody test is a blood test used to detect specific antibodies called smooth muscle antibodies (SMAs; also called anti-smooth muscle antibodies-ASMA) in your blood. These antibodies are produced by the immune system and mistakenly attack healthy cells in the liver, which can cause inflammation and damage. This test helps doctors diagnose autoimmune hepatitis (AIH), a long-term liver condition where the body’s immune system attacks the liver.

    Normally, the immune system defends the body against harmful invaders like viruses and bacteria. However, in autoimmune diseases like AIH, it produces autoantibodies like ASMAs that target the body’s own tissues by mistake. Autoimmune hepatitis can lead to serious complications like liver scarring (cirrhosis) if not treated early. Treatment often includes medications that reduce immune system activity, which helps protect the liver from further damage.

    There are two types of AIH:

    • Type 1 , the most common form, involves ASMAs and affects adults and children, especially women.

    • Type 2 , less common, is mainly seen in girls during childhood and involves other antibodies like liver-kidney microsomal antibody (LKM-1).

    Anti Smooth Muscle Antibody test is ordered along with tests for other autoantibodies, such as antinuclear antibody (ANA) and LKM-1 antibody, to confirm the diagnosis.

    If you are residing in Bangalore, you can get the Anti Smooth Muscle Antibody test at home with easy sample collection and quick results, making testing convenient and accessible.

    Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test Parameters

    The Anti-Smooth Muscle Antibody test measures a specific parameter: the presence of antibodies targeting smooth muscle proteins in the blood.

    The name “smooth muscle antibodies” comes from the fact that these antibodies attack certain proteins located in smooth muscle. Smooth muscles are present in the walls of hollow organs like the stomach, intestines, and blood vessels. These proteins are also present in large amounts in liver cells, so high levels of ASMAs can be a sign of liver disease, especially AIH.

    This test helps find out if the body's defence system is mistakenly attacking the liver. To get a clearer diagnosis, this test is often done along with other antibody tests, like the ANA test and LKM-1 test.

    There are different ways to check for ASMA, which help identify specific antibodies and how strong they are, which can give more information about the liver condition.

    Since ASMA was first found in people with liver diseases, it has helped in understanding and managing AIH. This test allows for early detection, which helps prevent serious liver problems like liver damage, scarring (cirrhosis) and liver failure. If ASMA is found, treatment is given to control the immune system and protect the liver.

    Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test Preparation

    To get ready for the Anti Smooth Muscle Antibody test, here are a few things you should know:

    • Prerequisites :

    There are no special requirements, such as fasting, needed before taking the Anti Smooth Muscle Antibody test.

    • Best Time to Get Tested :

    The Anti Smooth Muscle Antibody test can be taken at any time during the day.

    • Who Should Get an Anti Smooth Muscle Antibody Test? :

    Anti Smooth Muscle Antibody test is recommended for people with liver disease symptoms like jaundice, fatigue, or abdominal pain, and those with abnormal liver test results to check for AIH.

    • Cautions Before Taking an Anti Smooth Muscle Antibody Test :

    There are absolutely no special precautions necessary before undergoing this Anti Smooth Muscle Antibody test.

    Why Take the Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test?

    The Anti Smooth Muscle Antibody test is recommended when you experience symptoms of liver damage like:

    • Fatigue

    • Jaundice

    • Abdominal pain

    • Aching or stiffness in joints

    • Nausea

    • Loss of appetite

    • Dark-coloured urine

    • Light-coloured stool

    • Skin conditions (rashes, acne, vitiligo, or psoriasis)

    In the early stages, AIH may not show clear symptoms. However, if routine blood tests, like a Comprehensive Metabolic Panel, indicate liver abnormalities, an ASMA test might be necessary. If ASMA are detected, additional tests, including a liver biopsy, may be required to determine the extent of liver damage.

    FAQs on Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test in Bangalore

    The cost of the Anti-Smooth Muscle Antibody test in Bangalore is ₹2000. This price covers quick home sample collection within 60 minutes from booking. Orange Health Labs guarantees test results will be delivered within 84 hours post-sample collection.

    Yes, Orange Health Labs provides home sample collection for the Anti-Smooth Muscle Antibody test. After booking, a skilled eMedic expert will arrive at your home within 60 minutes for sample collection.

    The Anti-Smooth Muscle Antibody test helps diagnose autoimmune hepatitis by detecting antibodies that attack liver cells. It also assesses liver damage and determines if further tests, like a biopsy, are needed.

    Fasting is not required for undergoing the Anti-Smooth Muscle Antibody test.

    Follow these steps to book an Anti-Smooth Muscle Antibody test through Orange Health Labs:

    • Find the Test: Search for "Anti-Smooth Muscle Antibody test" and choose Orange Health Labs from the listed options.

    • Confirm Booking: Provide personal details, select your area, and pick a suitable time for sample collection.

    • Sample Collection: A trained eMedic professional will visit your specified location to collect the blood sample.

    • Testing and Reports: The collected sample will be analysed at our NABL-certified, ICMR-approved laboratory. Test results will be sent via email or WhatsApp within 84 hours of sample collection.

    Normal levels for the Anti Smooth Muscle Antibody test are typically "negative," meaning no antibodies are found. A "positive" result indicates the presence of autoantibodies, which may suggest autoimmune hepatitis or other liver-related conditions.

    Results for the Anti Smooth Muscle Antibody Test are generally provided within 84 hours following sample collection.

    The necessity for repeat testing is determined based on your health condition and your physician’s guidance.

    The Anti Smooth Muscle Antibody test measures the presence of autoantibodies against smooth muscle proteins.

    The Anti-Smooth Muscle Antibody test is accessible across various locations in Bangalore, covering Adugodi, Banashankari, Bannerghatta, Basavanagudi, Bellandur, BTM Layout, Chamrajpet, Cottonpet, CV Raman Nagar, Frazer Town, Giri Nagar, Hebbal, Domlur, Electronic City, Hennur, Hosur, HSR Layout, Jakkur, Jalahalli, Jaya Nagar, Kadugodi, Kammanahalli, Kengeri, Koramangala, Mahalakshmi Layout, Madiwala, Magadi Road, Malleshwaram, Marathahalli, Mathikere, Mysore Road, Nagarbhavi, Nandhini Layout, Old Airport Road, Peenya, RT Nagar, Rajaji Nagar, Rajarajeshwari Nagar, Sadashivnagar, Sahakara Nagar, Sanjay Nagar, Sarjapur, Seshadripuram, Shanthi Nagar, Shivaji Nagar, Sri Nagar, Tyagarajnagar, Uttarahalli, Vasanth Nagar, Vidyaranyapura, Vijaya Nagar, Whitefield, Yelahanka, Yeshwantpur.

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    References

    1. Smooth Muscle Antibody (SMA) Test: MedlinePlus Medical Test. 2. Anti-smooth muscle antibody - UF Health.  Available from:  https://medlineplus.gov/lab-tests/smooth-muscle-antibody-sma-test/
    2. Zhang WC, Zhao FR, Chen J, Chen WX. Meta-Analysis: Diagnostic Accuracy of Antinuclear Antibodies, Smooth Muscle Antibodies and Antibodies to a Soluble Liver Antigen/Liver Pancreas in Autoimmune Hepatitis.  Available from:  https://pmc.ncbi.nlm.nih.gov/articles/PMC3961308/#s4