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    What is Cardiolipin antibody IgA Test?

    The Cardiolipin Antibody IgA test detects the presence of antibodies against cardiolipins in the blood. These antibodies are mistakenly produced by the immune system and attack cardiolipins, which are phospholipids important for blood clotting. This attack can result in abnormal blood clotting and the depletion of platelets (which play a key role in clotting), leading to bleeding problems. High levels of cardiolipin antibodies are often found in individuals with abnormal blood clotting, autoimmune diseases such as systemic lupus erythematosus (SLE), or those with recurrent miscarriages.

    Cardiolipin antibodies are often associated with primary antiphospholipid syndrome (APS) and in conditions like SLE. The detection of these antibodies helps in diagnosing conditions like APS and can help explain recurrent thrombosis or miscarriage in affected individuals. This test is also relevant in monitoring autoimmune diseases and infections where anticardiolipin antibodies are found.

    Individuals in Bangalore seeking a diagnosis of clotting disorders are recommended to schedule a Cardiolipin Antibody IgA test at home.

    Cardiolipin antibody IgA Test Parameters

    The Cardiolipin Antibody IgA test measures the levels of IgA antibodies against cardiolipins, which are phospholipids crucial for normal blood clotting.

    Cardiolipin antibodies are a group of autoantibodies associated with thrombosis. These antibodies are produced by the immune system mistakenly, leading to the formation of abnormal blood clots. Elevated levels of IgA cardiolipin antibodies are often associated with autoimmune diseases and can play a role in the pathogenesis of these conditions. This test helps in diagnosing and monitoring APS and other clotting disorders.

    Cardiolipin antibody IgA Test Preparation

    Prepare for the Cardiolipin Antibody IgA test at home with these precautions:

    • Prerequisites : Fasting is not required for the Cardiolipin Antibody IgA test.

    • Best Time to Get Tested : The Cardiolipin Antibody IgA test can be taken at any convenient time.

    • Who Should Get a Cardiolipin Antibody IgA Test? : The Cardiolipin Antibody IgA test is recommended for individuals with unexplained or recurrent blood clots, including both venous and arterial thrombosis. This test is important for those diagnosed with autoimmune diseases such as SLE, where cardiolipin antibodies are often present, as well as for individuals suspected of having APS.

    • Cautions Before Taking a Cardiolipin Antibody IgA Test : Inform your doctor regarding the medicines and supplements that you take before undergoing the test.

    Why Take the Cardiolipin antibody IgA Test?

    The Cardiolipin Antibody IgA test helps diagnose conditions related to abnormal blood clotting or bleeding, particularly in individuals with recurrent miscarriages or unexplained thrombotic events. Testing is essential to:

    • Investigate frequent or unexplained blood clots or bleeding.

    • Identify potential causes in individuals with a history of recurrent miscarriages.

    • Diagnose conditions like SLE or APS, which are often associated with cardiolipin antibodies.

    • Understand the role of anti-phospholipid antibodies in thrombotic events, especially in those without major thrombotic symptoms.

    • Detect high levels of IgA antibodies, which may indicate underlying autoimmune conditions or unexplained thrombosis.

    • Evaluate the potential for false-positive VDRL (syphilis) tests, commonly seen in lupus patients with anti-cardiolipin antibodies.

    FAQs on Cardiolipin antibody IgA Test in Bangalore

    The cost of the Cardiolipin Antibody IgA test in Bangalore is ₹1000. This price includes rapid home sample collection and timely delivery of test results.

    Yes, home sample collection is available for Cardiolipin Antibody IgA test at home. A trained eMedic will arrive at your location within 60 minutes of booking to collect your sample.

    The Cardiolipin Antibody IgA test detects the presence of IgA antibodies against cardiolipins in the blood, which are associated with abnormal blood clotting. This test is used to diagnose conditions such as antiphospholipid syndrome, autoimmune diseases like systemic lupus erythematosus, and recurrent miscarriages, among others.

    Fasting is not necessary for the Cardiolipin Antibody test.

    To book a Cardiolipin Antibody IgA test with Orange Health Labs, follow these steps:

    • Find the Test: Search for the “Cardiolipin Antibody IgA test” and select Orange Health Labs from the available options.

    • Confirm Your Appointment: Enter your details, select your location, and schedule a convenient time for sample collection.

    • Sample Collection: A trained eMedic will visit at your location to collect the sample.

    • Laboratory Analysis: The sample will be sent to an NABL-accredited, ICMR-approved laboratory for testing.

    • Receive Results: The test results will be delivered to you via email or WhatsApp within 97 hours.

    The normal levels for the Cardiolipin Antibody test are as follows:

    • Negative: <10 units

    • Positive: ≥10 units

    A positive result indicates the presence of cardiolipin antibodies, which could be associated with conditions like antiphospholipid syndrome or autoimmune disorders.

    The results of the Cardiolipin Antibody IgA test are typically available within 97 hours after sample collection.

    The frequency of the Cardiolipin Antibody IgA test depends on your doctor’s recommendations. It may be performed periodically to monitor autoimmune diseases, blood clotting issues, or recurrent miscarriages.

    The Cardiolipin Antibody IgA test specifically measures the levels of IgA antibodies against cardiolipins in the blood, which can indicate conditions such as antiphospholipid syndrome and other autoimmune disorders. 10. In which localities can I get the Cardiolipin Antibody IgA test done in Bangalore?

    Orange Health Labs offers home sample collection for the Cardiolipin Antibody IgA test across several localities in Bangalore, including Adugodi, Banashankari, Bannerghatta, Basavanagudi, Bellandur, BTM Layout, Chamrajpet, Cottonpet, CV Raman Nagar, Frazer Town, Giri Nagar, Hebbal, Domlur, Electronic City, Hennur, Hosur, HSR Layout, Jakkur, Jalahalli, Jaya Nagar, Kadugodi, Kammanahalli, Kengeri, Koramangala, Mahalakshmi Layout, Madiwala, Magadi Road, Malleshwaram, Marathahalli, Mathikere, Mysore Road, Nagarbhavi, Nandhini Layout, Old Airport Road, Peenya, RT Nagar, Rajaji Nagar, Rajarajeshwari Nagar, Sadashivnagar, Sahakara Nagar, Sanjay Nagar, Sarjapur, Seshadripuram, Shanthi Nagar, Shivaji Nagar, Sri Nagar, Tyagarajnagar, Uttarahalli, Vasanth Nagar, Vidyaranyapura, Vijaya Nagar, Whitefield, Yelahanka, Yeshwantpur.

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    References

    1. Cardiolipin Antibody - Health Encyclopedia - University of Rochester Medical Center.  Available from:  https://www.urmc.rochester.edu/encyclopedia/content?contenttypeid=167&contentid=cardiolipin_antibody
    2. Anti-cardiolipin antibody (ACL) - South Tees Hospitals NHS Foundation Trust.  Available from:  https://www.southtees.nhs.uk/services/pathology/tests/anti-cardiolipin-antibody-acl/
    3. Andreoli L, Fredi M, Nalli C, Piantoni S, Rossella Reggia, Dall’Ara F, et al. Clinical Significance of IgA Anti-Cardiolipin and IgA Anti-β2Glycoprotein I Antibodies. Current Rheumatology Reports.  Available from:  https://pubmed.ncbi.nlm.nih.gov/23754504/