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    CD 20, Flow Cytometry5143252051% off
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    What is CD 20, Flow Cytometry Test?

    A CD20 blood test measures the amount of CD20, a protein found on the surface of B-cells, a type of white blood cell. CD20 plays an important role in the immune system by helping B-cells grow and mature. This test is primarily used to diagnose and monitor B-cell-related cancers, such as lymphoma.

    Lymphomas are cancers that begin in the lymphatic system, which is a part of the body’s immune system. B-cell lymphomas occur when B-cells become cancerous. While most B-cells have CD20 on their surface, the amount can vary depending on the lymphoma type. Some lymphoma cells have lower CD20 levels, which can affect their response to CD20-targeted treatments, like rituximab.

    The CD20 Marker Flow Cytometry test is usually done flow cytometry. This method measures how much CD20 is on the B-cells and if there are any changes in how the protein is expressed. This information can help guide treatment decisions for lymphoma patients. For example, if the CD20 protein is low or missing, the doctor may choose a different treatment that might work better.

    If you are living in Bangalore, you can get the CD20 test done at home with prompt sample collection and delivery of results.

    CD 20, Flow Cytometry Test Parameters

    The CD20 test measures only one parameter: the CD20 cell count measured as both an absolute count and a percentage of lymphocytes.

    CD20 is a protein that is found on the surface of B-cells, which are important for the immune system’s ability to fight infections. 1 It first appears when B-cells are developing and plays a vital role in their activation, growth, and maturation. However, when B-cells eventually transform into plasma cells (the final stage of their development) they lose the CD20 protein. This loss makes CD20 a useful marker for understanding the development of B-cells. CD20 is also found on a smaller group of T-cells, another type of immune cell, but its primary role is in B-cells.

    The amount of CD20 expression can vary between different types of B-cell cancers, and this variation can help guide treatment decisions. Apart from being a marker, CD20 is believed to assist in regulating B-cell function, including helping calcium enter the cells. This process is essential for B-cells to carry out their job of fighting infections effectively.

    CD 20, Flow Cytometry Test Preparation

    Before taking the CD20 test at home, it is important to know the following guidelines:

    • Prerequisites

    Unlike some other tests, the CD20 test does not require fasting or any other special preparations.

    • Best Time to Get Tested

    The CD20 test can be taken at any time during the day, as there are no specific timing restrictions.

    • Who Should Get a CD20 Test?

    People who have symptoms of certain types of blood cancer, like lymphoma or leukaemia, may need a CD20 test for diagnosis and treatment of their condition.

    • Cautions Before Taking a CD20 Test

    There are no specific precautions that need to be followed before taking the CD20 test.

    Why Take the CD 20, Flow Cytometry Test?

    The CD20 blood test is useful for diagnosing and monitoring B-cell-related diseases, including various types of lymphoma.

    • Helps Diagnose Lymphoma : The CD20 test is important for identifying different lymphoma subtypes, especially B-cell lymphomas.

    • Guides Treatment Decisions : It helps the doctor determine if you are likely to respond to therapies like rituximab, improving treatment outcomes.

    • Monitors Disease Progression : The test can track lymphoma progression and determine treatment efficacy.

    • Identifies High-Risk Patients : CD20 expression levels can help assess increased risk, thus guiding treatment adjustments accordingly.

    • Assesses Treatment Effectiveness : If CD20 levels are low or discordant, it may mean the treatment is less effective, prompting a change in treatment.

    • Helps With Personalised Therapy : By measuring CD20 levels, doctors can tailor treatments more specifically to individual needs, improving overall survival rates.

    Taking the CD20 Marker Flow Cytometry blood test gives crucial information about your health status, especially if you are dealing with lymphoma or related diseases. It ensures you receive the right treatment at the right time, potentially improving your prognosis and quality of life.

    FAQs on CD 20, Flow Cytometry Test in Bangalore

    The price of a CD20 test in Bangalore is ₹2520. This fee includes rapid home sample collection, which will be completed within 60 minutes of your booking. Orange Health Labs ensures that you receive your test results within 73 hours after sample collection.

    Yes, Orange Health Labs provides home sample collection for the CD20 test. After booking, a trained eMedic will visit your home within 60 minutes to collect your sample.

    A CD20 test helps identify and monitor B-cell disorders, including leukaemia, lymphoma, and immune conditions, by measuring CD20 protein levels on B lymphocytes.

    Fasting is not required prior to taking the CD20 Test.

    Booking a CD20 Test with Orange Health Labs is easy. Follow these steps to book the test: • Search for the Test : Look for the "CD20 test" and select the Orange Health Labs listing from the options. • Confirm Your Booking : Provide your details, choose your location, and pick a time and place that works best for you for sample collection. • Sample Collection : A professional eMedic will visit your home to collect your blood sample. • Analysis and Results : The sample will be processed at our NABL-accredited, ICMR-approved laboratory, and the results will be sent to you via email or WhatsApp within 73 hours of collection.

    Normal levels for the CD20 test are typically 5.0–22.3% for CD20 cell percentage and 74.4–441.1 cells/µL for absolute CD20 count.

    Typically, the test results will be available within 73 hours after your sample has been collected.

    The frequency of CD20 testing varies based on your specific medical condition and the advice provided by your doctor.

    The CD20 test measures the percentage and absolute count of CD20 cells present in lymphocytes.

    The CD20 test is offered in various areas of Bangalore, including, but not limited to, Adugodi, Banashankari, Bannerghatta, Basavanagudi, Bellandur, BTM Layout, Chamrajpet, Cottonpet, CV Raman Nagar, Frazer Town, Giri Nagar, Hebbal, Domlur, Electronic City, Hennur, Hosur, HSR Layout, Jakkur, Jalahalli, Jaya Nagar, Kadugodi, Kammanahalli, Kengeri, Koramangala, Mahalakshmi Layout, Madiwala, Magadi Road, Malleshwaram, Marathahalli, Mathikere, Mysore Road, Nagarbhavi, Nandhini Layout, Old Airport Road, Peenya, RT Nagar, Rajaji Nagar, Rajarajeshwari Nagar, Sadashivnagar, Sahakara Nagar, Sanjay Nagar, Sarjapur, Seshadripuram, Shanthi Nagar, Shivaji Nagar, Sri Nagar, Tyagarajnagar, Uttarahalli, Vasanth Nagar, Vidyaranyapura, Vijaya Nagar, Whitefield, Yelahanka, Yeshwantpur.

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    References

    1. The Evaluation of CD3, CD 5, CD10, CD 19, and CD20 Markers in the Differential Diagnosis of the Lymphoma Subtypes in Sudanese Patients. International Journal of Biomedicine.  Available from:  https://www.researchgate.net/publication/356962786_The_Evaluation_of_CD3_CD_5_CD10_CD_19_and_CD20_Markers_in_the_Differential_Diagnosis_of_the_Lymphoma_Subtypes_in_Sudanese_Patients
    2. Comparative Assessment of Surface CD19 and CD20 Expression on B-Cell Lymphomas from Clinical Biopsies: Implications for Targeted Therapies. Blood.  Available from:  https://ashpublications.org/blood/article/134/Supplement_1/5345/425075/Comparative-Assessment-of-Surface-CD19-and-CD%2020
    3. Diffuse large B-cell lymphoma: reduced CD20 expression is associated with inferior survival.  Available from:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943836/
    4. The regulation and function of CD20: an “enigma” of B-cell biology and targeted therapy. Haematologica.  Available from:  https://www.haematologica.org/article/view/9425
    5. Seegmiller AC, Hsi ED, Craig FE. The current role of clinical flow cytometry in the evaluation of mature B‐cell neoplasms.  Available from:  https://onlinelibrary.wiley.com/doi/full/10.1002/cyto.b.21756
    6. Lee AYS. CD20+ T cells: an emerging T cell subset in human pathology. Inflammation research.  Available from:  https://pmc.ncbi.nlm.nih.gov/articles/PMC9616751/#Sec18