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    What Is the Angiotensin Converting Enzyme (ACE) Test?

    The Angiotensin Converting Enzyme (ACE) test is used to measure the concentration of ACE in your blood, a protein responsible for regulating blood pressure. ACE is produced by the cells that line your blood vessels, but high levels of it can indicate a condition called sarcoidosis. This disease causes immune cells to form clusters, or granulomas, in various organs, particularly the lungs, which can result in health complications. Elevated ACE levels are often seen in individuals with active sarcoidosis, with 50% to 80% of patients showing increased levels. If your doctor suspects sarcoidosis due to symptoms like a prolonged cough, difficulty breathing, or joint pain, the ACE test may be recommended.

    Elevated ACE levels can also be a sign of other health conditions, such as infections like tuberculosis or exposure to certain chemicals. If ACE levels are high, further tests may be necessary to determine the cause.

    While ACE is naturally present in the body, ACE inhibitors, a type of medication used to treat high blood pressure, can block ACE’s action and may influence the test results.

    If you are located in Delhi and experiencing symptoms such as a persistent cough, shortness of breath, or joint pain, you may wish to book an ACE test in Delhi to help identify inflammatory conditions such as sarcoidosis.

    Angiotensin Converting Enzyme (ACE) Test Parameters

    The ACE test measures the amount of angiotensin-converting enzyme present in the blood.

    ACE is a protein that regulates blood pressure by converting angiotensin I into angiotensin II. This process leads to the narrowing of blood vessels and an increase in blood pressure. Most ACE is found in the lungs, although it is also present in other regions of the body. People under 20 generally have higher ACE levels, but these levels tend to decrease and stabilise as they get older.

    ACE is also produced by certain immune cells when there is infection or inflammation. These cells form small clusters, known as granulomas, which can be seen in conditions such as sarcoidosis, where granulomas are primarily found in the lungs and other organs.

    Angiotensin Converting Enzyme (ACE) Test Preparation

    When preparing for an Angiotensin Converting Enzyme test, consider the following:

    Prerequisites

    There is no need for fasting before this test.

    Best Time to Get Tested The Angiotensin Converting Enzyme test can be performed at any time during the day, according to your convenience.

    Who Should Get an Angiotensin Converting Enzyme Test? This test is typically recommended for those experiencing symptoms like unexplained shortness of breath, chronic coughing, joint pain, or unexplained weight changes, which may point to conditions like sarcoidosis or other related health issues.

    Cautions Before Taking Angiotensin Converting Enzyme Test No specific precautions are necessary prior to taking the Angiotensin Converting Enzyme test.

    Why Take the Angiotensin Converting Enzyme (ACE) Test?

    The ACE test is used to check for sarcoidosis or other diseases that may lead to the formation of granulomas, small clusters of immune cells in various organs that can cause a range of symptoms. If you are experiencing any of the following, the ACE test may be beneficial:

    • Persistent cough, shortness of breath, or wheezing

    • Severe tiredness

    • Unexplained weight loss or loss of appetite

    • Chest pain

    • Joint stiffness or soreness

    • Vision problems

    • Dry mouth

    • Headaches

    • Unusual skin changes such as rashes, sores, or hardened spots

    • Fever

    This test is particularly important for people between the ages of 20 and 40, as sarcoidosis most commonly affects individuals in this age group. It can also be used to differentiate sarcoidosis from other granuloma-related conditions, such as infections.

    For individuals with sarcoidosis who initially had high ACE levels, repeating the test is useful for tracking the progression of the disease and assessing how well treatment is working.

    FAQs on the Angiotensin Converting Enzyme (ACE) Test in Delhi

    The cost of the Angiotensin Converting Enzyme test in Delhi is ₹1232. This includes home sample collection, which will occur within 60 minutes of booking confirmation. Results will be provided within 72 hours from the time of sample collection.

    Yes, Orange Health Labs facilitates home sample collection for the Angiotensin Converting Enzyme test at home. A qualified eMedic will come to your location to collect the sample within 60 minutes after booking, based on available time slots.

    The Angiotensin Converting Enzyme test measures the levels of ACE in the blood, which can aid in diagnosing conditions like sarcoidosis, lung diseases, and liver disorders. Elevated ACE levels are often linked to various medical conditions that lead to inflammation in the body.

    To book the Angiotensin Converting Enzyme test, follow these steps: • Search for the test: Go to the Orange Health website and select the Angiotensin Converting Enzyme test. • Confirm your booking: Provide your details, choose a convenient time slot, and confirm your appointment. • Sample collection: After booking confirmation, a trained eMedic will be assigned to collect your sample from your location. • Laboratory processing: Your blood sample will be processed at an ICMR-certified, NABL-accredited laboratory. • Receive results: Results will be sent to you via email or WhatsApp within 72 hours of sample collection and will be accessible on the Orange Health app.

    Normal ACE levels in the blood generally range from 12 to 68 units per litre (u/L).

    Once you’ve booked the Angiotensin Converting Enzyme test, an eMedic will collect your sample within 60 minutes. The results will be available within 72 hours after the sample is collected.

    The frequency of the Angiotensin Converting Enzyme test will depend on your health condition and individual circumstances. It’s best to consult your doctor for advice.

    The Angiotensin Converting Enzyme test measures one parameter: the level of angiotensin-converting enzyme in your blood.

    Orange Health offers home sample collection for the Angiotensin Converting Enzyme test in multiple locations throughout Delhi, including areas such as Chandni Chowk, Connaught Place, Defence Colony, Dwarka, Greater Kailash, Green Park, Hauz Khas, Janakpuri, Rajouri Garden, Rohini, Safdarjung Enclave, Shahdara, South Extension, Kalkaji, Karol Bagh, Lajpat Nagar, Malviya Nagar, Mayur Vihar, Nehru Place, Preet Vihar, and Vasant Kunj.

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    References

    1. Angiotensin converting enzyme (ACE) | Pathology Tests Explained [Internet].  Available from:  https://www.pathologytestsexplained.org.au/ptests-pro.php?q=ACE+%28Angiotensin+converting+enzyme%29
    2. Angiotensin Converting Enzyme (Blood) [Internet].  Available from:  https://www.urmc.rochester.edu/encyclopedia/content?ContentTypeID=167&ContentID=angiotensin_converting_enzyme_blood
    3. Kahkouee S, Samadi K, Alai A, Abedini A, Rezaiian L. Serum ACE Level in Sarcoidosis Patients with Typical and Atypical HRCT Manifestation. Polish Journal of Radiology [Internet].  Available from:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036380/