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    What is Anti-HBc IgM Test?

    The Anti-HBc IgM test is a blood test that detects IgM antibodies, which are produced by the immune system when the body encounters a recent infection with the hepatitis B virus (HBV). Hepatitis B is a common viral infection that mainly affects the liver. Upon exposure to the virus, the immune system generates antibodies to fight the infection. IgM antibodies are produced specifically against the hepatitis B core antigen (HBcAg), appearing shortly after symptoms arise. These antibodies can remain in the bloodstream for up to six months after the infection.

    In acute hepatitis B infections, IgM anti-HBc levels rise rapidly and can remain detectable for weeks to months, indicating a recent infection that occurred within the past six months. While the presence of HBsAg is common, it may be undetectable in some cases. During an acute infection, elevated liver enzyme levels are common, and IgM anti-HBc can still be detected even if HBsAg levels become undetectable. A non-reactive result suggests that there is no recent infection, but it does not rule out chronic hepatitis B. In patients with chronic hepatitis B, IgM anti-HBc may appear temporarily during periods of reactivation. This test is useful for distinguishing acute HBV infection from other types of hepatitis infections.

    This test is particularly helpful for individuals showing liver dysfunction symptoms or those who have been at risk of contracting the hepatitis B virus.

    Anti-HBc IgM Test Parameters

    The Anti-HBc IgM test measures the presence of IgM antibodies in the blood, which are produced by the immune system during the early stages of a hepatitis B virus (HBV) infection. These antibodies appear typically within six months of infection and act as an indicator of recent exposure to the virus. A positive Anti-HBc IgM result suggests acute hepatitis B, while in chronic cases, it may indicate a flare-up or reactivation of the infection.

    Upon infection with the hepatitis B virus, the immune system generates specific antibodies to combat the virus. There are two primary types of antibodies: IgM and IgG. IgM antibodies are the first to appear during an acute infection and fade after roughly six months. On the other hand, IgG antibodies remain in the body long-term, indicating that the person either has a past infection or has chronic hepatitis B.

    The Anti-HBc IgM test is essential for diagnosing acute hepatitis B, particularly when patients show symptoms of liver issues or have been recently exposed to the virus. Early detection through this test is key for initiating the right treatment and preventing further complications.

    Anti-HBc IgM Test Preparation

    When preparing for the Anti-HBc IgM test, please consider the following:

    Prerequisites: Fasting is not necessary before the Anti-HBc IgM test. No special preparations are needed.

    Best Time to Get Tested: You can arrange the Anti-HBc IgM test at any time of the day, as there are no strict timing constraints.

    Who Should Get an Anti-HBc IgM Test?: Individuals showing symptoms of hepatitis, having abnormal liver test results, recently exposed to hepatitis B, living in areas with a high risk of hepatitis B, or blood donors needing a screening should get this test.

    Cautions Before Taking Anti-HBc IgM Test: No particular precautions are required before taking the Anti-HBc IgM test.

    Why Take the Anti-HBc IgM Test?

    The Anti-HBc IgM test is recommended for:

    • Individuals recently exposed to hepatitis B : Whether through contact with infected individuals or medical exposure.

    • People showing hepatitis symptoms : These can include jaundice, tiredness, fever, loss of appetite, stomach discomfort, nausea, and aching joints.

    • Residents in high-prevalence areas : Where it’s essential to differentiate between acute and chronic hepatitis B for accurate diagnosis.

    • Individuals with abnormal liver function tests : Indicating a possible hepatitis B infection.

    • Blood donors : Routine screening in blood donation centres ensures blood safety.

    This test is essential for identifying recent HBV infections, enabling early detection and effective treatment.

    FAQs on Anti-HBc IgM Test in Delhi

    The Anti-HBc IgM test in Delhi costs ₹1130. This price includes the benefit of home sample collection, which will occur within 60 minutes of booking confirmation. The test results will be provided within 30 hours after the sample is collected.

    Yes, Orange Health Labs offers home sample collection for the Anti-HBc IgM test in Delhi. A qualified eMedic will visit your location within 60 minutes after confirming your booking, depending on the available time slots.

    The Anti-HBc IgM test is used to diagnose recent hepatitis B infections, particularly those occurring within the past 6 months. It is also used to monitor chronic carriers and detect any transition from inactive to active HBV infection. A positive result indicates a recent infection, while a negative result excludes recent infection but doesn’t rule out the possibility of chronic hepatitis B.

    No, fasting is not required before taking the Anti-HBc IgM test.

    Here’s how you can book your Anti-HBc IgM test:

    • Search for the test : Visit the Orange Health website and select the Anti-HBc IgM test.

    • Confirm your booking : Enter your details, choose a convenient time for the sample collection, and confirm your booking.

    • Sample collection : A trained eMedic will be assigned to visit your location for sample collection after your booking is confirmed.

    • Processing in the laboratory : The sample will be processed at a certified, NABL-accredited laboratory.

    • Get results : Your Anti-HBc IgM test results will be available within 30 hours via email or WhatsApp.

    A normal Anti-HBc IgM test result is negative (< 5 PEIU/ml), indicating that there has been no recent hepatitis B infection. An equivocal result (5–9 PEIU/ml) suggests a possible early infection or a resolving one, while a positive result (≥ 10 PEIU/ml) indicates a recent acute infection.

    After you book your Anti-HBc IgM test, an eMedic will collect the sample from your location within 60 minutes of confirmation. The results will be delivered within 30 hours of the sample collection.

    The need for repeat testing depends on individual health circumstances.

    The Anti-HBc IgM test specifically measures the presence of Anti-HBc IgM antibodies in your blood.

    Orange Health provides home sample collection for the Anti-HBc IgM test across numerous areas in Delhi, such as Connaught Place, Chandni Chowk, Karol Bagh, Lajpat Nagar, South Extension, Greater Kailash, Hauz Khas, Saket, Vasant Kunj, Dwarka, Rohini, Pitampura, Janakpuri, Rajouri Garden, Mayur Vihar, Preet Vihar, Shahdara, Laxmi Nagar, Green Park, Safdarjung Enclave, Defence Colony, New Friends Colony, Kalkaji, Malviya Nagar, Nehru Place.

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    References

    1. HBc IgM (Anti-Hepatitis B core IgM) | Newfoundland & Labrador Public Health Laboratory.  Available from:  https://publichealthlab.ca/reportingname/hbc-igm-anti-hepatitis-b-core-igm/
    2. CDC. Clinical Testing and Diagnosis for Hepatitis B.  Available from:  https://www.cdc.gov/hepatitis-b/hcp/diagnosis-testing/index.html
    3. Hepatitis B Foundation. Hepatitis B Foundation: Understanding Your Hepatitis B Test Results. https://www.hepb.org/prevention-and-diagnosis/diagnosis/understanding-your-test-results/  Available from:  https://www.hepb.org/prevention-and-diagnosis/diagnosis/understanding-your-test-results/
    4. Hepatitis B Foundation. Hepatitis B Foundation: Hepatitis B Blood Tests.  Available from:  https://www.hepb.org/prevention-and-diagnosis/diagnosis/hbv-blood-tests/
    5. Clinical Significance and Remaining Issues of Anti-HBc Antibody and HBV Core-Related Antigen. Diagnostics.  Available from:  https://www.mdpi.com/2075-4418/14/7/728
    6. Hepatitis Panel: MedlinePlus Lab Test Information.  Available from:  https://medlineplus.gov/lab-tests/hepatitis-panel/