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    Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA2924262510% off
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    What Is Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test?

    The Anti Neutrophil Cytoplasmic Antibody (ANCA) test is a blood test used to find specific proteins made by the immune system. These proteins usually help fight infections, but sometimes they mistakenly attack healthy white blood cells, including neutrophils and monocytes.

    The test is important for diagnosing ANCA-associated vasculitis, a condition where blood vessels become inflamed, which can lead to narrowing, blockages, or weakening. If this happens, it may harm organs such as the kidneys, lungs, skin, and eyes. Early signs include tiredness, fever, weight loss, and body pain. If left untreated, vasculitis can cause serious damage to these organs.

    Two main proteins are connected to ANCA-associated vasculitis:

    • Myeloperoxidase (MPO): Mostly found in microscopic polyangiitis (MPA), which affects small blood vessels.

    • Proteinase 3 (PR3): More common in granulomatosis with polyangiitis (GPA), a condition that affects the lungs and sinuses.

    To confirm the diagnosis and monitor treatment, additional tests may be needed, such as PR3 ANCA, kidney function tests, inflammation markers, and full blood counts.

    If you live in Delhi, you may find it convenient to have the ANCA test at home, with quick sample collection and timely results.

    Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test Parameters

    The ANCA test checks for specific autoantibodies (immune system proteins that mistakenly attack the body) in the blood. It mainly detects two types: PR3 and MPO.

    These autoantibodies target two important proteins:

    cANCA (cytoplasmic ANCA)

    Attacks PR3, a protein that helps regulate blood cell production and plays a role in programmed cell death.

    pANCA (perinuclear ANCA)

    Targets MPO, a protein essential for fighting infections.

    When ANCAs are present, they activate neutrophils (a type of white blood cell), making them release chemicals that cause inflammation and damage blood vessels. This process can harm organs like the lungs, kidneys, and skin. As neutrophils pass through blood vessel walls, they release more chemicals, making the inflammation and tissue damage worse.

    The levels of ANCA, PR3, and MPO can change over time, but even if they are undetectable in a test, some people may still produce these autoantibodies. While a positive ANCA test is usually linked to vasculitis, it can also occur in conditions like rheumatoid arthritis, inflammatory bowel disease, and infections such as endocarditis or respiratory infections. Certain medications may also trigger a positive result.

    Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test Preparation

    If you are planning to take the Anti Neutrophil Cytoplasmic Antibody (ANCA) test at home, here’s what you need to know:

    • Prerequisites : No special preparation is needed, and you do not have to fast before the test.

    • Best Time to Get Tested : The ANCA test can be done at any time of the day, whenever it is convenient for you.

    • Who Should Get an Anti Neutrophil Cytoplasmic Antibody (ANCA) Test: If you have fever, ongoing tiredness, joint pain, weight loss, or symptoms affecting your skin, kidneys, lungs, or nervous system, an ANCA test may be needed to rule out autoimmune vasculitis.

    • Cautions Before Taking an Anti Neutrophil Cytoplasmic Antibody (ANCA) Test : There are no special precautions to take before the ANCA test.

    Why Take the Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test?

    The ANCA test is recommended if you have:

    • Unexplained symptoms such as fatigue, fever, weight loss, muscle or joint pain, or night sweats.

    • Problems affecting specific organs:

      • Eyes, ears, and nose: Vision changes, frequent sinus infections, or hearing loss.

      • Skin: Rashes, itching, or bruising.

      • Lungs: Shortness of breath or coughing up blood.

      • Kidneys: Blood or protein in your urine.

      • Nervous system: Numbness, shooting pain, or tingling.

      • Digestive system: Stomach pain, diarrhoea, or vomiting blood.

    • Suspected vasculitis-related conditions, such as granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA).

    • Inflammatory bowel disease (IBD), especially if you have diarrhoea, blood in your stool, or a persistent fever.

    • Ongoing monitoring of autoimmune vasculitis if you have already been diagnosed.

    The ANCA test is crucial for detecting and managing vasculitis early, helping control symptoms and preventing serious organ damage.

    FAQs on Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test in Delhi

    The ANCA test in Delhi is available for ₹2625. This price covers a hassle-free home sample collection, which takes place within 60 minutes of booking. With Orange Health Labs, you’ll get your test results within 69 hours after your sample is collected.

    Yes, Orange Health Labs offers a convenient home sample collection service for the ANCA test. A certified eMedic professional will arrive at your home within 60 minutes of booking to collect your blood sample.

    The ANCA test is used to identify autoimmune conditions like vasculitis. It detects specific autoantibodies in the blood that can lead to inflammation and damage in blood vessels and organs.

    No, you do not need to fast before taking the ANCA test.

    Booking an ANCA test with Orange Health Labs is quick and easy if you follow these steps:

    • Find the Test: Search for the "Anti Neutrophil Cytoplasmic Antibody (ANCA) test" and choose the Orange Health Labs option from the results.

    • Confirm Your Appointment: Enter your details, select your location, and pick a convenient time for sample collection.

    • Sample Collection: A trained eMedic professional will visit your home or preferred location to collect your blood sample.

    • Analysis & Results: Your sample will be analysed at our NABL-accredited, ICMR-approved laboratory, and the results will be sent via email or WhatsApp within 69 hours of sample collection.

    A normal ANCA test result is negative, meaning no p-ANCA or c-ANCA autoantibodies are detected, which usually rules out autoimmune vasculitis. A positive result indicates their presence and requires further assessment for autoimmune conditions.

    The results for the ANCA test are typically ready within 69 hours after sample collection.

    How often you need the ANCA test depends on your specific medical condition and should be determined by your doctor.

    The ANCA test detects antibodies such as p-ANCA and c-ANCA, as well as PR3 and MPO antibodies.

    The ANCA test is available in multiple locations across Delhi, including but not limited to: Connaught Place, Chandni Chowk, Karol Bagh, Lajpat Nagar, South Extension, Greater Kailash, Hauz Khas, Saket, Vasant Kunj, Dwarka, Rohini, Pitampura, Janakpuri, Rajouri Garden, Mayur Vihar, Preet Vihar, Shahdara, Laxmi Nagar, Green Park, Safdarjung Enclave, Defence Colony, New Friends Colony, Kalkaji, Malviya Nagar, Nehru Place.

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    References

    1. Antineutrophil Cytoplasmic Antibodies (ANCA) Test: MedlinePlus Medical Test.  Available from:  https://medlineplus.gov/lab-tests/antineutrophil-cytoplasmic-antibodies-anca-test/
    2. Antineutrophil Cytoplasmic Antibodies (ANCA) Test: What It Is. 3. Antineutrophil cytoplasmic antibodies (ANCA) | Pathology Tests Explained. 4. Khalid N, Aeddula NR. Antinuclear Cytoplasmic Antibody [Internet]. PubMed. Treasure Island (FL). 5. The value of anti-neutrophil cytoplasmic antibodies (ANCA) testing for the diagnosis of ANCA-associated vasculitis, a systematic review and meta-analysis.  Available from:  https://my.clevelandclinic.org/health/diagnostics/22512-anca-test