Save Tax with full body checkups starting at ₹ 1099
Orange Health
Search for tests or checkups
 Tests
 Checkups
Support
    Anti Smooth Muscle antibody (Anti-SMA) (IFA)2626200024% off
    trust markerMins HomeCollection
    trust markerHappyCustomers
    trust markerGoogleRating
    trust markerCertifiedLabs

    What is Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test?

    The Anti Smooth Muscle Antibody (ASMA) test is a blood test designed to detect specific autoantibodies known as smooth muscle antibodies (SMAs). These antibodies, mistakenly produced by the immune system, attack healthy liver cells, leading to inflammation and potential damage. This test is crucial for diagnosing autoimmune hepatitis (AIH), a chronic liver condition where the body’s immune system erroneously targets the liver.

    Under normal circumstances, the immune system protects against external threats such as bacteria and viruses. However, in autoimmune disorders like AIH, it generates antibodies that attack the body’s tissues. Left untreated, AIH can result in severe complications, including liver fibrosis and cirrhosis. Treatment typically involves immunosuppressive medications that help control the immune response and prevent further liver damage.

    There are two forms of AIH:

    • Type 1, the more prevalent form, affects both adults and children, particularly women, and is associated with ASMAs.

    • Type 2, which is rarer, primarily affects young girls and involves additional antibodies such as liver-kidney microsomal antibody (LKM-1).

    To confirm an AIH diagnosis, doctors often order the ASMA test alongside other autoantibody tests, including antinuclear antibody (ANA) and LKM-1 antibody tests.

    If you're in Delhi, you can conveniently get this test done at home with easy sample collection and fast results.

    Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test Parameters

    The Anti-Smooth Muscle Antibody (ASMA) test detects the presence of antibodies that target smooth muscle proteins in the blood. These antibodies attack proteins commonly found in smooth muscle tissues, which line hollow organs such as the stomach, intestines, and blood vessels. Since these proteins are also abundant in liver cells, elevated levels of ASMAs may indicate liver disease, particularly autoimmune hepatitis (AIH).

    This test helps determine if the immune system is mistakenly attacking the liver. To ensure an accurate diagnosis, it is often performed alongside other antibody tests, such as ANA and LKM-1 tests.

    Different methods are available to assess ASMA, which helps identify specific antibodies and their intensity, providing deeper insights into liver conditions. Since its discovery in liver disease patients, ASMA testing has played a crucial role in understanding and managing AIH. Early detection through this test can help prevent severe complications like liver scarring (cirrhosis), liver damage, and failure. If ASMA is detected, treatment focuses on controlling the immune system to protect liver health.

    Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test Preparation

    Prepare for the Anti-Smooth Muscle Antibody test with these prerequisites:

    • Prerequisites :

    No fasting or special preparation is required before taking the test.

    • Best Time to Get Tested :

    You can take the ASMA test at any time of the day.

    • Who Should Get an Anti-Smooth Muscle Antibody Test? :

    The test is recommended for individuals experiencing symptoms of liver disease, such as jaundice, fatigue, and abdominal pain, or those with abnormal liver function test results to check for autoimmune hepatitis (AIH).

    • Cautions Before Taking an Anti-Smooth Muscle Antibody Test :

    There are no special precautions necessary before the test.

    Why Take the Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test?

    The Anti-Smooth Muscle Antibody (ASMA) test is recommended if you experience symptoms of liver damage, such as:

    • Jaundice (yellowing of the skin and eyes)

    • Chronic fatigue

    • Loss of appetite

    • Unusual joint pain or stiffness

    • Abdominal discomfort or pain

    • Nausea and digestive issues

    • Dark-coloured urine

    • Pale or light-coloured stool

    • Skin problems, including rashes, acne, vitiligo, or psoriasis

    In some cases, autoimmune hepatitis (AIH) doesn’t cause noticeable symptoms in its early stages. If a routine blood test, such as a Comprehensive Metabolic Panel (CMP), detects liver function abnormalities, an ASMA test may be needed for further evaluation. If ASMA is present, additional testing, such as a liver biopsy, might be required to assess liver damage.

    FAQs on Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test in Delhi

    The price for the Anti-Smooth Muscle Antibody test in Delhi is ₹2000. This includes a fast and hassle-free home sample collection within 60 minutes of booking. Test results will be available within 99 hours after sample collection.

    Yes, Orange Health Labs offers home sample collection for this test. A trained eMedic professional will visit your location within 60 minutes after booking.

    This test is primarily used to diagnose autoimmune hepatitis (AIH) by detecting antibodies that attack the liver. It also helps evaluate liver damage and determines whether further investigations, such as a liver biopsy, are necessary.

    No fasting is needed for this test; you can take it at any time of the day.

    Booking an Anti-Smooth Muscle Antibody test with Orange Health Labs in Delhi is simple:

    • Search for the test: Look up "Anti-Smooth Muscle Antibody test" and select Orange Health Labs.

    • Schedule your appointment: Enter your details, choose your location, and pick a convenient time for sample collection.

    • Sample collection at home: A trained eMedic professional will arrive at your address to collect the blood sample.

    • Testing and report delivery: Your sample will be processed at a NABL-certified, ICMR-approved lab, and the results will be sent via email or WhatsApp within 99 hours.

    A normal Anti-Smooth Muscle Antibody test result is typically negative, meaning no antibodies are detected. A positive result suggests the presence of autoantibodies, which may indicate autoimmune hepatitis or other liver-related disorders.

    The results for the Anti-Smooth Muscle Antibody test are usually available within 99 hours after sample collection.

    The need for repeat testing depends on your health condition and your doctor’s recommendation.

    This test detects autoantibodies against smooth muscle proteins, which help diagnose autoimmune conditions affecting the liver.

    The test is available in multiple locations across Delhi, including Connaught Place, Chandni Chowk, Karol Bagh, Lajpat Nagar, South Extension, Greater Kailash, Hauz Khas, Saket, Vasant Kunj, Dwarka, Rohini, Pitampura, Janakpuri, Rajouri Garden, Mayur Vihar, Preet Vihar, Shahdara, Laxmi Nagar, Green Park, Safdarjung Enclave, Defence Colony, New Friends Colony, Kalkaji, Malviya Nagar, Nehru Place.

    The Orange Health Experience

    Choose precision
    Not a pilot, just as precise
    No more painful pricks
    Trust our fully automated and certified labs
    Customers love us

    Choose precision

    On time, every time!

    • 98% on time collections with a 60 minutes promise
    • 99% reports are delivered on time within 6 hours

    Not a pilot, just as precise

    Meet our expert eMedics!

    • Hygienic, well groomed, and professional eMedics
    • With over 100 hours of training

    No more painful pricks

    Experience painless testing!

    • Our eMedics are trained for a single, painless prick.
    • Don’t believe us? We asked our customers and here is what they said - 98% of customers experienced no pain during sample collection!
    • The most organised sample collection box and experience

    Trust our fully automated and certified labs

    For accurate testing

    • Certified labs
    • eQAS partnership with AIIMS and CMC Vellore
    • We have our own fully automated labs in all 4 cities we are available in

    Customers love us

    The highest rated lab!

    • Google rating: 4.9/5 (16000+ reviews)
    • 1 million+ customers tested
    4.9
    Google Rating

    Highest Rated Diagnostic Lab

    Payment & Refund Policy

    • We do not accept cash payments
    • All modes of online payment are accepted
    • Refunds will be credited back to the source of payment within 3 hours of order cancellation.

    References

    1. Smooth Muscle Antibody (SMA) Test: MedlinePlus Medical Test. 2. Anti-smooth muscle antibody - UF Health.  Available from:  https://medlineplus.gov/lab-tests/smooth-muscle-antibody-sma-test/
    2. Zhang WC, Zhao FR, Chen J, Chen WX. Meta-Analysis: Diagnostic Accuracy of Antinuclear Antibodies, Smooth Muscle Antibodies and Antibodies to a Soluble Liver Antigen/Liver Pancreas in Autoimmune Hepatitis.  Available from:  https://pmc.ncbi.nlm.nih.gov/articles/PMC3961308/#s4