Can Vitamin B12 supplements be harmful if taken in excess?

Vitamin B12 is a water-soluble vitamin, meaning that excess amounts are usually excreted through urine, making toxicity rare. However, extremely high doses of supplements can occasionally lead to side effects such as acne, skin rashes, or digestive discomfort. In most cases, it is safe even at higher doses, but it’s essential to follow your doctor’s recommendation, especially if you have any underlying health conditions. Those taking large doses should monitor their levels with regular testing.