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Typhidot Test


A Typhidot test is processed for Salmonella typhi. This test detects antibodies against Salmonella typhi. Learn more about Typhidot test here.


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What is the Typhidot test? 

A typhidot test is done to detect IgM and IgG antibodies against Salmonella typhi, the bacteria that causes typhoid fever. Typhoid mainly spreads through contaminated food and water and manifests in the form of fever, loss of appetite, stomach pain, and diarrhoea. This test shows results within 1-3 days of infection. It identifies the IgM and IgG antibodies that indicate recent infections.

What are the other names for the Typhidot test? 

The other names are Typhoid test and S. Typhi antibody test.

What are the test parameters included in the Typhidot test?

There is only one parameter.

 

What does a Typhidot test measure?

The Typhidot test analyses IgG and IgM antibodies against Salmonella typhi. These antibodies are produced against the outer membrane protein of Salmonella typhi. This test usually shows the infection within 2-3 days. It detects IgM and IgG antibodies separately. The presence of IgM antibodies indicates a recent infection, while the presence of IgG antibodies indicates a previous or remote infection.

 

This test is not a quantitative test; it is a qualitative test. It only detects the presence or absence of Salmonella typhi. A Widal test would be recommended in this case to check the specific titres of the antibodies required.       

 

What’s the normal range of Typhidot test? 

Positive or Negative

Who should get a Typhidot test? 

A typhidot test is useful in detecting antibodies in the first week of illness. It helps in the early diagnosis of the conditions, which enables the doctors to initiate prompt treatment of typhoid and paratyphoid fever. This test is performed when the individual is present with the following symptoms:

  • Fever with pain in the body, particularly in the legs and head

  • Increased fever with sleepiness and weakness in the body

  • Bloating sensation with pain in the abdomen

  • Slow rise in the body temperature (step ladder pattern) for 4 to 5 days.

  • A relatively slow pulse in comparison to the rising body temperature.

  • A small red boil or rash on the abdomen and back appears after one week of fever.

Are there any preparations needed for the Typhidot test?

No special preparation is required. Fasting is not required for this test.


What is the cost of a Typhidot test?

What is the type of sample required? 

This test requires a blood sample.

Who processes the Typhidot test?

A healthcare provider, who is also called a phlebotomist, usually performs blood draws, including those for typhidot tests, but any healthcare provider trained in drawing blood can perform this task. These samples are sent to a lab where a medical laboratory scientist prepares the samples and performs the tests on analysers or manually.

What should I expect during my Typhidot test?

You may expect to experience the following during the blood test or a blood draw:

  • You have to sit comfortably on the chair, and the phlebotomist will check your arms for an easily accessible vein. It is the inner part of the arm on the other side of your elbow.

  • Once the phlebotomist has located a vein, they will disinfect the area with an alcohol swab.

  • They will insert the needle into your vein to draw a blood sample. This can feel like a small pinch.

  • After they insert the needle, the required amount of blood will be drawn into a test tube.

  • When they have drawn enough blood for the test, they’ll remove the needle and hold a cotton ball or gauze on the site to stop any bleeding.

  • They will apply a band-aid over the pricked site, and the blood collection is finished.

This process takes less than five minutes.

 

What should I expect after my Typhidot test?

Once the phlebotomist has collected the blood sample, it will be sent to the laboratory for processing or testing. When the reports are ready, your healthcare provider will share the results with you.

What are the risks of a Typhidot test?

These blood tests are common, and they don’t carry any significant risks. You might have a slight pain like an ant bite when the needle gets inserted, and a small bruise can develop there.

When can I expect my Typhidot test results?

At Orange Health, peripheral smear test reports are available within 6 hours.

What do the results of a Typhidot test mean? 

 

Interpretation 

A typhidot test for immunochromatography detects IgG and IgM antibodies against the Salmonella bacterial antigen of an outer membrane protein. 

The typhidot-M test is another variation of the typhidot test that helps in the diagnosis of the acute phase of typhoid infection. 

 

Normal result

 A negative result for Anti-Salmonella IgG and IgM antibodies indicates no infection.

 

Abnormal result

  • A positive result for IgM antibodies indicates acute infection.

A positive result for IgG antibodies indicates a past infection or a chronic infection.

Since this test gives a positive result for IgG antibodies present in the blood due to the past infection, it cannot be differentiated between the infection that occurred previously and a current infection or a chronic infection.

 

A typhidot M test is superior compared to a typhidot test as it detects only the IgM antibodies present in the blood during the acute phase of the illness. However, both tests are much more effective in the diagnosis of typhoid at an early stage compared to a blood culture test.

 

According to the studies, a typhidot can be used for the early detection of typhoid, particularly in areas where typhoid is frequently seen.

 

What are normal Typhidot test results?

Positive or Negative

 

The normal ranges can vary slightly among different laboratories. Some of the labs use different measurements or might do tests on the different samples. Speak to your healthcare provider about the meaning of your specific test results.

 

What other tests might I have along with this test?

Blood Culture, Widal Test

 

How do I book a Typhidot test at home?

Log on to www.orangehealth.in and submit your details. Our highly trained, professional, and vaccinated eMedics will be at your doorstep within 60 minutes or at the time booked by you.

Frequently Asked Questions on Typhidot Test

What is the Typhidot test?

Typhidot (or widal test) is a rapid test for the diagnosis of typhoid fever. A Typhidot test is a dot Elisa kit that detects IgM and IgG antibodies against the outer membrane protein (OMP) of Salmonella typhi. This typhidot test is expected to become positive within 2 - 3 days of infection. 

 

What are Typhidot IgM and IgG positives?

Typhidot IgM test measures the level of the IgM antibody in the blood and is indicative of current typhoid infection. The typhidot IgG test analyses the level of IgG antibodies in the blood. A Typhidot IgG is indicative of past typhoid infection.

 

Which is better, Widal or typhidot test?

Both the Typhidot and Widal tests are sensitive tests for diagnosing typhoid fever. But the typhidot test is a rapid test and it is very easy to perform as compared to the widal test. However, the culture isolation of Salmonella remains essential, especially it is for antibiotic susceptibility testing, and these serological tests should be used in conjunction with culture for the early diagnosis of enteric fever (typhoid). 

 

What is IgM in typhoid?

A Typhidot IgM test is done to detect antibodies against Salmonella typhi. This test detects the present or absent infection of Salmonella typhi. A Salmonella typhi is responsible for causing typhoid fever. 

 

Can a CBC test detect typhoid?

Yes, Complete blood counts can detect typhoid infection. A complete blood count (CBC) shows an increased number of white blood cells (WBC) in the blood if one has typhoid.

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